Results 181 to 190 of about 11,091 (232)

Potent antitumor activity of synthetic 1,2-Naphthoquinones and 1,4-Naphthoquinones

Bioorganic & Medicinal Chemistry, 2003
Rhinacanthone (1) and two 1,2-pyranonaphthoquinones (2,3) were synthesized and found to show very potent cytotoxicity against three cancer cell lines (KB, HeLa and HepG(2)) with IC(50) values of 0.92-9.63 microM, whereas the corresponding hydroxylated derivative 4 had reduced cytotoxicity (IC(50) values of 7.61-24.13 microM).
Ngampong, Kongkathip, Boonsong, Kongkathip, Pongpun, Siripong, Chak, Sangma, Suwaporn, Luangkamin, Momad, Niyomdecha, Suppachai, Pattanapa, Suratsawadee, Piyaviriyagul, Palangpon, Kongsaeree   +8 more
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1,4-Naphthoquinone

2001
[130-15-4] C10H6O2 (MW 158.16) InChI = 1S/C10H6O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6H InChIKey = FRASJONUBLZVQX-UHFFFAOYSA-N (dienophile used to synthesize various aromatic rings via Diels–Alder or cycloaddition-type reactions;1 undergoes amination,2 allylation,3 cyclooligomerization,4 and Thiele–Winter acetoxylation to give ...
Erica Caldwell, Laurent Deloux, Morris Srebnik   +2 more
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Naphthoquinones from juglandaceae

Phytochemistry, 1986
Abstract The oligomeric juglones isolated from the barks of Juglandaceae plants, Pterocarya and Juglans , were shown to be 3,3′-bijuglone (8,8′-dihydroxy[2,2′-binaphthalene]-1,1′,4,4′-tetrone and unsymmetrical cyclotrijuglone ( 1,7,16-trihydroxy-5,6,11,12,17,18-trinaphthalenehexone).
Kiyoichi Hirakawa, Eriko Ogiue, Jiro Motoyoshiya, Masao Yajima   +3 more
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Naphthoquinone metabolites of the fungi

Phytochemistry, 1998
Structures and physico-chemical properties of 100 naphthoquinone metabolites produced by filamentous fungi are reviewed. The conditions of pigment formation, biogenesis and the mechanism of biosynthesis of pigments by fungi are described. Sixty-three fungi cultures able to produce naphthoquinone are listed.
A G, Medentsev, V K, Akimenko
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A spiro-linked pyrene–naphthoquinone

Acta Crystallographica Section C Crystal Structure Communications, 2000
The title molecule, 2'-pyrenylspiro[2, 3-dihydro-1H-cyclopenta[b]naphthalene-2,5'-1',3'-dioxane]-4,9-dione, C(32)H(22)O(4), contains an electron-donating pyrene group spiro-linked to an electron-accepting naphthoquinone. The molecules are V-shaped in profile and stack to form columns along b with alternating, approximately coplanar, pyrene and ...
J A, Potenza, T J, Emge, J, Albaneze, S, Knapp, H J, Schugar   +4 more
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Naphthoquinones ofLithospermum erythrorhizon

Chemistry of Natural Compounds, 1976
1. The roots ofLithospermum erythrorhizon Sieb. et Zucc. have yielded six naphthazarin pigments which have been characterized as shikonin itself and derivatives of it. A new quinoid pigment of nonnaphthazarin structure has also been isolated.
O. E. Krivoshchekova, S. A. Fedoreev, V. A. Denisenko, O. B. Maksimov, P. G. Gorovoi   +4 more
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Novel Naphthoquinones from Conospermum incurvum

Journal of Natural Products, 1994
During the reisolation of the trimeric naphthoquinone derivative conocurvone [1] from an extract of the Australian shrub Conospermum incurvum, six monomeric naphthoquinones were isolated. These include three novel 1,4-naphthoquinone derivatives: 3-methyl-14,15-dihydro-15-hydroxyteretifolione B [3], 3-methyl-14,15-dihydro-15-hydroxyteretifolione B ...
J R, Dai, L A, Decosterd, K R, Gustafson, J H, Cardellina, G N, Gray, M R, Boyd   +5 more
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ChemInform Abstract: 1,4‐NAPHTHOQUINONES, VII. C‐METHYLATION OF 1,4‐NAPHTHOQUINONES

Chemischer Informationsdienst, 1984
AbstractNaphthochinone (I) werden mit DMSO in Gegenwart des Fenton‐ Reagens (FeSO4/H202) C‐methyliert.
G. WURM, U. GERES
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Enzymatic desymmetrization/resolution of epoxydiols derived from 1,4-naphthoquinone, 5-hydroxy-1,4-naphthoquinone and 5,8-dihydroxy-1,4-naphthoquinone

Tetrahedron: Asymmetry, 2004
Abstract The enzymatic desymmetrization/resolution of epoxydiols generated from the basic epoxidation and reduction of 1,4-naphthoquoinone, 5-hydroxy-1,4-naphthoquinone and 5,8-dihydroxy-1,4-naphthoquinone is described. 2,3-Epoxy-1α,2α,3α,4α-tetrahydronaphthalene-1,4-diol and 5,8-diallyloxy-2,3-epoxy-1α,2α,3α,4α-tetrahydronaphthalene-1,4-diol were ...
Russell L. Betts, Sean T. Murphy, Carl R. Johnson   +2 more
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Dihydroxyacetone Naphthoquinone Protection against Photosensitivity

Dermatology, 1976
30 patients with multiple types of sunlight sensitivity were treated successfully with DHA/lawsone sunscreen. This sunscreen was able to protect all patients even though their photosensitivities were in different parts of the ultraviolet and visible spectrum. About 80% of the patients experienced sufficient protection during the summer months to lead a
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