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A spiro-linked pyrene–naphthoquinone

Acta Crystallographica Section C Crystal Structure Communications, 2000
The title molecule, 2'-pyrenylspiro[2, 3-dihydro-1H-cyclopenta[b]naphthalene-2,5'-1',3'-dioxane]-4,9-dione, C(32)H(22)O(4), contains an electron-donating pyrene group spiro-linked to an electron-accepting naphthoquinone. The molecules are V-shaped in profile and stack to form columns along b with alternating, approximately coplanar, pyrene and ...
J A, Potenza   +4 more
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Tubulin‐Perturbing Naphthoquinone Spiroketals

Chemical Biology & Drug Design, 2008
Several natural and synthetic naphthoquinone spiroketals are potent inhibitors of the thioredoxin–thioredoxin reductase redox system. Based on the antimitotic and weak antitubulin actions noted for SR‐7 ([8‐(furan‐3‐ylmethoxy)‐1‐oxo‐1,4‐dihydronaphthalene‐4‐spiro‐2′‐naphtho[1″,8″‐de][1′,3′][dioxin]), a library of related compounds was screened for ...
Raghavan, Balachandran   +4 more
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A Second Naphthoquinone in Spinach Chloroplasts

Nature, 1964
DURING the chromatography of lipids from spinach chloroplasts we have observed a compound which appears to be a form of vitamin K which is different from the well-known vitamin K1. The latter has previously been isolated from chloroplasts1,2 and is widely distributed in green plants3.
M, MCKENNA, M D, HENNINGER, F L, CRANE
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Reactions of 1,4-naphthoquinone and 5-hydroxy-1,4-naphthoquinone with ninhydrin

Russian Chemical Bulletin, 2019
1,4-Naphthoquinone and 5-hydroxy-1,4-naphthoquinone react with ninhydrin to give 2-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)naphthalene-1,4-dione and 8-hydroxy- 2-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)naphthalene-1,4-dione, respectively.
L. M. Gornostaev   +5 more
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In Vitro Cytotoxicities of 1,4‐Naphthoquinone and Hydroxylated 1,4‐Naphthoquinones to Replicating Cells

Journal of Applied Toxicology, 1993
AbstractUsing the human hepatoma cell line, HepG2, and the BALB/c mouse fibroblast cell line, 3T3, as the bioindicators in the neutral red cytotoxicity assay, the effect of hydroxyl substitution on the toxicity of 1,4‐naphthoquinone was studied.
H, Babich, A, Stern
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Oxidative Aminotrifluoromethylation of 1,4-Naphthoquinone

The Journal of Organic Chemistry
A strategy for convenient and precise oxidative aminotrifluoromethylation of 1,4-naphthoquinone with the Togni reagent and amines has been demonstrated via a radical process. This method allows efficient access for the preparation of a wide range of CF3-functionalized 1,4-naphthoquinones under mild conditions, and its application in late-stage ...
Lin Tang   +6 more
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Naphthoquinone derivatives from SPP.: bisisodiospyrin, a tetrameric naphthoquinone

Tetrahedron Letters, 1970
K. Yoshihira, Michiko Tezuka, S. Natori
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Naphthoquinones

2000
Johann Grolig, Rudolf Wagner
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Naphthoquinone Antimalarials. XIV. 2-Hydroxy-3-aryl-1,4-naphthoquinones

Journal of the American Chemical Society, 1948
H E, ZAUGG, R T, RAPALA, M T, LEFFLER
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Naphthoquinone series

Proceedings of the Indian Academy of Sciences - Section A, 1954
B. Suryanarayana, B. D. Tilak
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