Results 91 to 100 of about 782 (172)

Regulación de los transportadores de fosfato mediante receptores nucleares LXR y FXR [PDF]

, 2013
La homeostasis del fosfato inorgánico (Pi) se controla mediante una serie de mecanismos neuroendocrinos, que actúan sobre el intestino, hueso y riñón.
Caldas Zuleta, Yupanqui Alberto, Sorribas Alejaldre, Víctor   +1 more
core   +1 more source

The Innovator - Summer 2021 [PDF]

, 2021
Newsletter published by the Offices of Faculty Affairs & Researchhttps://scholarlycommons.libraryinfo.bhs.org/facultyaffairs_newsletters/1007/thumbnail ...
Litera, Allison
core   +1 more source

Immunohistochemical analysis of NaPi2b protein (MX35 antigen) expression and subcellular localization in human normal and cancer tissues.

Experimental oncology, 2012
To study the expression profile of the NaPi2b protein and its localization in breast, ovarian and lung cancer cells in relation to normal tissues adjacent to tumor.Immunohistochemical analysis with monoclonal antibody MX35 was applied for investigation of NaPi2b protein expression in breast, lung and ovarian carcinomas.
Kiyamova, R., Shyian, M., Lyzogubov, V.V., Usenko, V.S., Gout, T., Filonenko, V.   +5 more
openaire   +2 more sources

Data from The Dolaflexin-based Antibody–Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b

, 2023
<div>Abstract<p>Target selection for antibody–drug conjugates (ADC) frequently focuses on identifying antigens with differential expression in tumor and normal tissue, to mitigate the risk of on-target toxicity. However, this strategy restricts the possible target space.
Timothy B. Lowinger, Donald A. Bergstrom, Ling Xu, Jian Xu, Dongmei Xiao, Alex Uttard, Elena Ter-Ovanesyan, Cheri A. Stevenson, LiuLiang Qin, Marina Protopova, Laura L. Poling, Peter U. Park, Dennis McGillicuddy, Winnie Lee, Venu R. Gurijala, Dmitry R. Gumerov, Michael J. DeVit, Damon R. Demady, Patrick R. Conlon, Charlie Bu, Mao Yin, Aleksandr V. Yurkovetskiy, Rebecca Mosher, Natalya D. Bodyak   +23 more
openaire   +1 more source

Supplementary Figures from The Dolaflexin-based Antibody–Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b

, 2023
Natalya D. Bodyak, Rebecca Mosher, Aleksandr V. Yurkovetskiy, Ying Mao, Charlie Bu, Patrick R. Conlon, Damon R. Demady, Michael J. DeVit, Dmitry R. Gumerov, Venu R. Gurijala, Winnie Lee, Dennis J. McGillicuddy, Peter U. Park, Laura L. Poling, Marina Protopova, LiuLiang Qin, Cheri A. Stevenson, Elena Ter‐Ovanesyan, Alex Uttard, Dongmei Xiao, Jian Xu, Ling Xu, Donald A. Bergstrom, Timothy B. Lowinger   +23 more
openalex   +2 more sources

75P Possible significance of the proline at position 325 in the recognition of the MX35 epitope of the NaPi2b transporter by monoclonal antibodies

, 2023
L.F. Bulatova, I. Slidzyuk, А. А. Коротаева, V. Skripova, M. Bogdanov, R. Kiyamova   +5 more
openalex   +1 more source

TP037/#453 Up-next (GOG-3049/ENGOT-OV71-NSGO-CTU): a study of upifitamab rilsodotin (UPRI), a NaPi2b -directed antibody drug conjugate (ADC) in platinum-sensitive recurrent ovarian cancer [PDF]

, 2022
Debra L. Richardson, Philipp Harter, David M. O’Malley, Antonio González‐Martín, Thomas J. Herzog, Caroline Rogalski, Robert A. Burger, Mansoor Raza Mirza   +7 more
openalex   +1 more source

2022-RA-459-ESGO UPLIFT (ENGOT-ov67/GOG-3048) a registrational trial of Upifitamab Rilsodotin (XMT-1536; UpRi), a NaPi2b-directed antibody drug conjugate (ADC) in platinum-resistant ovarian cancer [PDF]

, 2022
Nicole Concin, Bradley J. Monk, Mansoor Raza Mirza, Robert L. Coleman, Isabelle Ray‐Coquard, Bhavana Pothuri, Jean‐François Baurain, José Alejandro Pérez Fidalgo, David Cibula, Antonella Saverse, Susana Banerjee, Radek Madry, Christian Marth, Emily Putiri, J. D. Barrett, Leslie R. DeMars, Debra J. Richardson   +16 more
openalex   +1 more source

Drogas Conjugadas com Anticorpos no Tratamento do Câncer: Uma Revisão de Literatura [PDF]

Introdução: A imunoterapia oncológica tem se consolidado como uma das principais abordagens terapêuticas no tratamento do câncer. Entre seus avanços, destacam-se os anticorpos conjugados a drogas (ADCs), que combinam especificidade molecular à ação ...
Alonso, Matheus Felipe, Borges, Larissa Ribeiro Soares, Donzelli, Renato Vieira, Kuranishi, Maria Eduarda, Medeiros, Caylani Tatiara Martins de, Meirelles, Izadora Cruz, Milan, Nycollas Russo, Sant'Ana, Paula Grippa, Silva, Maria Eduarda Peripolli da   +8 more
core   +2 more sources

2024 ACVIM Forum Research Abstract Program

Journal of Veterinary Internal Medicine, Volume 38, Issue 5, Page 2840-2970, September/October 2024.
wiley   +1 more source