Antibody engineering & therapeutics, the annual meeting of the antibody society December 7-10, 2015, San Diego, CA, USA [PDF]
The 26th Antibody Engineering & Therapeutics meeting, the annual meeting of The Antibody Society united over 800 participants from all over the world in San Diego from 6-10 December 2015.
Bakker, J +9 more
core +1 more source
Radioimmunotherapy with an 211At‐labeled anti–tissue factor antibody protected by sodium ascorbate
Although the astatinated anti–tissue factor (TF) monoclonal antibody (mAb) was disrupted by an astatine‐211–induced radiochemical reaction, we demonstrated that the immunoconjugates eluted in 0.6 or 1.2% sodium ascorbate (SA) solution were protected from antibody denaturation, which contributed to maintaining their cellular binding and antitumor ...
Hiroki Takashima +15 more
wiley +1 more source
Background. Papillary thyroid carcinoma (PTC) usually has an indolent clinical course, yet a subset of patients might show an aggressive course. Thus, better stratification of at‐risk patients is mandatory for proper management. Solute carrier family 34 member 2 (SLC34A2) is an independent prognostic indicator in several cancers.
Sarah Adel Hakim +4 more
wiley +1 more source
Radioimmunoterapy: a promising therapeutic approach to treat ovarian carcinoma [PDF]
O cancro do ovário é a neoplasia ginecológica com maior índice de mortalidade entre a população do sexo feminino apesar dos consideráveis progressos verificados no seu tratamento.
Oliveira, Maria Cristina +1 more
core +2 more sources
180 Real-world treatment patterns and outcomes with first-line maintenance olaparib for BRCAm advanced ovarian cancer: a pan-European study (OVAL-1) [PDF]
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Asselain, B +9 more
core +1 more source
Intestinal and renal adaptations to changes of dietary phosphate concentrations in rat [PDF]
We have studied the role of the intestine, kidney, and several hormones when adapting to changes in dietary P concentration. Normal and parathyroidectomized (PTX) rats were fed pH-matched diets containing 0.1%, 0.6%, and 1.2% P concentrations.
Chopo-Escuin, Gema +4 more
core +1 more source
Core-shell hydrogel microfiber-expanded pluripotent stem cell-derived lung progenitors applicable to lung reconstruction in vivo [PDF]
ヒトiPS細胞由来肺前駆細胞の拡大培養とマウス肺への移植・生着に成功 --肺再生医療の実現へ大きな一歩--. 京都大学プレスリリース. 2021-07-30.Lung transplantation is the only treatment available for end-stage lung diseases; however, donor shortage is a global issue.
Gotoh, Shimpei +9 more
core +1 more source
Effects of kidney disease and dietary inulin treatment on transcellular phosphorus transporters [PDF]
Introduction: Chronic Kidney Disease – mineral bone disorder (CKD-MBD) is marked by biochemical abnormalities, bone alterations, and vascular calcifications. We recently showed that the fermentable fiber inulin lowered circulating phosphorus.
Biruete, Annabel +4 more
core +1 more source
Isolation and functional properties of highly-purified N-terminal domain of human NaPi2b by scalable "resin overload" technique. [PDF]
Despite the enthusiasm and advances in the purification of native and engineered full-length membrane proteins, little attention has been paid to their fragments which could serve as attractive inspiration for function, regulation, or targeting of full-length membrane protein with therapeutic antibodies (Abs).
Savenkova D +4 more
europepmc +3 more sources
In vitro modelling of respiratory infections in idiopathic pulmonary fibrosis (IPF) using human induced pluripotent stem cell (hiPSCs)-derived alveolar epithelial type II cells [PDF]
Idiopathic pulmonary fibrosis (IPF) is a chronic, interstitial lung disease estimated to affect 4.5 individuals per 10,000[1]. It is characterised by the accumulation of extracellular matrix in the lung interstitium, which disrupts the normal ...
Serna Valverde, Ana Lilia
core +3 more sources

