Effect of CKD-MBD therapies on the gastrointestinal expression of phosphate transporters [PDF]
, 2021 Background: Chronic kidney disease-mineral and bone disorder (CKD-MBD) is prevalent and encompasses biochemical abnormalities, bone alterations, and vascular calcifications.
Biruete, Annabel +3 more
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The FASEB Journal, 2016 Inorganic phosphate (Pi) plays an important role in growth, development, bone formation and cellular metabolism. A physiological phosphate balance is maintained through the multi‐organ communication among intestine, kidneys and bones. Dysregulation of phosphate balance can induce many disorders ranging from osteoporosis to cardiovascular calcification.
Saif I. Al‐Juboori +5 more
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STEM CELLS Translational Medicine, Volume 9, Issue 8, Page 867-881, August 2020., 2020 This review highlights the current concepts and advances in the research fields of human lung alveoli. Combination of in vitro human lung alveolar model systems with single‐cell technologies of “omics” approaches will improve our understanding of normal human lung development, maintenance and regeneration, paving the way for future therapeutic repair ...
Kelly V. Evans, Joo‐Hyeon Lee
wiley +1 more source
iPSC-derived mesenchymal cells that support alveolar organoid development [PDF]
, 2022 肺胞オルガノイドをつくることができるヒトiPS細胞由来間葉細胞の作成. 京都大学プレスリリース. 2022-10-12.Mesenchymal cells are necessary for organ development. In the lung, distal tip fibroblasts contribute to alveolar and airway epithelial cell differentiation and homeostasis.
Gotoh, Shimpei +10 more
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The peculiarities of gene expression of medullary breast carcinoma tumor-associated antigens in different types of breast tumors [PDF]
, 2012 Aim. To investigate gene expression profile of human medullary breast carcinoma’s tumor-associated antigens in different histological types of breast tumors.
Antoniuk, A.V. +6 more
core +1 more source
MA09.10 A NaPi2b Antibody-Drug Conjugate Induces Durable Complete Tumor Regressions in Patient-Derived Xenograft Models of NSCLC [PDF]
Journal of Thoracic Oncology, 2017 Donald A. Bergstrom +11 more
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Supplementary Tables from Phase Ia Study of Anti-NaPi2b Antibody–Drug Conjugate Lifastuzumab Vedotin DNIB0600A in Patients with Non–Small Cell Lung Cancer and Platinum-Resistant Ovarian Cancer [PDF]
, 2023 David E. Gerber +26 more
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Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment
Advanced Science, Volume 12, Issue 34, September 11, 2025.Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu +7 more
wiley +1 more source
Modern approaches in suicidal gene therapy of malignant neoplasms
Успехи молекулярной онкологииOne of the promising directions in antitumor therapy is suicidal gene therapy based on the introduction of cytotoxic genes into tumor cells. Most often, these genes encode for enzymes of bacterial or viral origin, capable of direct or indirect killing of
E. V. Dudkina +2 more
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Deregulated Renal Calcium and Phosphate Transport during Experimental Kidney Failure.
PLoS ONE, 2015 Impaired mineral homeostasis and inflammation are hallmarks of chronic kidney disease (CKD), yet the underlying mechanisms of electrolyte regulation during CKD are still unclear.
Wilco P Pulskens +8 more
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