Understanding the promising role of antibody drug conjugates in breast and ovarian cancer. [PDF]
A nascent category of anticancer therapeutic drugs called antibody-drug conjugates (ADCs) relate selectivity of aimed therapy using chemotherapeutic medicines with high cytotoxic power.
Aggarwal, A +11 more
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Phosphate toxicity and tumorigenesis [PDF]
, 2018 The final publication is available at Elsevier via http://dx.doi.org/10.1016/j.bbcan.2018.04.007 © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/In this article, we ...
Brown, Ronald B., Razzaque, Mohammed S.
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Supplementary Figure 2 from Phase Ia Study of Anti-NaPi2b Antibody–Drug Conjugate Lifastuzumab Vedotin DNIB0600A in Patients with Non–Small Cell Lung Cancer and Platinum-Resistant Ovarian Cancer [PDF]
, 2023 David E. Gerber +26 more
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Display Technologies for the Selection of Monoclonal Antibodies for Clinical Use [PDF]
, 2017 The development and improvement of strategies related to discovery technologies of monoclonal antibodies (mAbs) (phage display, yeast display, ribosome display, bacterial display, mammalian cell surface display, mRNA display, DNA display, transgenic ...
dos , Mariana Lopes +2 more
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Skin Sodium and Hypertension: a Paradigm Shift? [PDF]
, 2018 PURPOSE OF REVIEW: Dietary sodium is an important trigger for hypertension and humans show a heterogeneous blood pressure response to salt intake.
Connolly, Kathleen +3 more
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Neither absence nor excess of FGF23 disturbs fetal phosphate metabolism in mice until after birth [PDF]
, 2020 Fibroblast growth factor 23 (FGF23) plays an important role in maintaining phosphate homeostasis in adults largely though actions on the kidneys to excrete phosphate and reduce calcitriol.
Ma, Yue
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3P NaPi2b expression in high grade serous ovarian cancer: Results from combined data sets [PDF]
, 2023 Susana Banerjee +13 more
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Experimental oncology, 2009 The identification of markers that are specifically expressed by different histological types of epithelial ovarian cancer (EOC) may lead to the development of novel and more specific diagnostic and therapeutic strategies. Sodium-dependent phosphate transporter NaPi2b (or MX35 ovarian cancer antigen) is a novel perspective marker of EOC.
Gryshkova, V. +9 more
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Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability [PDF]
, 2018 Hyperphosphatemia is common in patients with chronic kidney disease and is increasingly associated with poor clinical outcomes. Current management of hyperphosphatemia with dietary restriction and oral phosphate binders often proves inadequate. Tenapanor,
Alexander, RT +30 more
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Trans-omics biomarker model improves prognostic prediction accuracy for early-stage lung adenocarcinoma [PDF]
, 2019 Limited studies have focused on developing prognostic models with trans-omics biomarkers for early-stage lung adenocarcinoma (LUAD). We performed integrative analysis of clinical information, DNA methylation, and gene expression data using 825 early ...
Alolga, Raphael N., +26 more
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