Results 81 to 90 of about 820 (178)

81P Effect of disulfide bonds and N-glycosylation on the recognition of the NaPi2b transporter by monoclonal antibodies [PDF]

, 2022
D. Reshetnikova, L.F. Bulatova, V. Skripova, D. Savenkova, A.K. Nurgalieva, M. Bogdanov, R. Kiyamova   +6 more
openalex   +1 more source

Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability [PDF]

, 2018
Hyperphosphatemia is common in patients with chronic kidney disease and is increasingly associated with poor clinical outcomes. Current management of hyperphosphatemia with dietary restriction and oral phosphate binders often proves inadequate. Tenapanor,
Alexander, RT, Behrendt, M, Caldwell, JS, Donowitz, M, Dragoli, D, Greasley, PJ, He, Y, Hernando, N, Jafri, Q, Jönsson-Rylander, AC, Karlsson, D, King, AJ, Knöpfel, T, Kohler, J, Koo-McCoy, S, Kozuka, K, Kumaraswamy, P, Lewis, JG, Marks, J, Minassian, NA, Nie, B, O’Neill, D, Pan, D, Pastor Arroyo, EM, Plain, A, Rosenbaum, DP, Ryden-Bergsten, T, Siegel, M, Strömstedt, M, Wagner, CA, Wang, J   +30 more
core  

Mechanisms of Lymphatic Metastasis and Immune Microenvironment Regulation in Ovarian Cancer: From Molecular Mechanisms to Precision Lympho-Immune Surgery [PDF]

Ovarian cancer is a highly prevalent and lethal malignancy in women, with lymphatic metastasis representing one of the key determinants of patient prognosis.
Ge, Dongxia, He, Yuedong, Li, Lin, Xi, Mingrong, Yang, Bowen, You, Zongbing   +5 more
core   +2 more sources

Supplementary Figure 2 from Phase Ia Study of Anti-NaPi2b Antibody–Drug Conjugate Lifastuzumab Vedotin DNIB0600A in Patients with Non–Small Cell Lung Cancer and Platinum-Resistant Ovarian Cancer [PDF]

, 2023
David E. Gerber, Jeffrey R. Infante, Michael S. Gordon, Sarah B. Goldberg, Miguel Martín, Enriqueta Felip, Maria Martinez‐García, Joan H. Schiller, David R. Spigel, Julie Cordova, Valerie Westcott, Yulei Wang, David S. Shames, YounJeong Choi, Robert L. Kahn, Randall Dere, Divya Samineni, Jian Xu, Kedan Lin, Katie Wood, Stephanie Royer‐Joo, Vanessa Lemahieu, Eva Schuth, Anjali Vaze, Daniel Maslyar, Eric W. Humke, Howard A. Burris   +26 more
openalex   +2 more sources

Data from Phase Ia Study of Anti-NaPi2b Antibody–Drug Conjugate Lifastuzumab Vedotin DNIB0600A in Patients with Non–Small Cell Lung Cancer and Platinum-Resistant Ovarian Cancer

, 2023
David E. Gerber, Jeffrey R. Infante, Michael Gordon, Sarah B. Goldberg, Miguel Martín, Enriqueta Felip, Maria Martinez‐García, Joan H. Schiller, David R. Spigel, Julie Cordova, Valerie Westcott, Yulei Wang, David S. Shames, YounJeong Choi, Robert L. Kahn, Randall Dere, Divya Samineni, Jian Xu, Kedan Lin, Katie Wood, Stephanie Royer‐Joo, Vanessa Lemahieu, Eva Schuth, Anjali Vaze, Daniel Maslyar, Eric W. Humke, Howard A. Burris   +26 more
openalex   +2 more sources

Regulación de los transportadores de fosfato mediante receptores nucleares LXR y FXR [PDF]

, 2013
La homeostasis del fosfato inorgánico (Pi) se controla mediante una serie de mecanismos neuroendocrinos, que actúan sobre el intestino, hueso y riñón.
Caldas Zuleta, Yupanqui Alberto, Sorribas Alejaldre, Víctor   +1 more
core   +1 more source

Trans-omics biomarker model improves prognostic prediction accuracy for early-stage lung adenocarcinoma [PDF]

, 2019
Limited studies have focused on developing prognostic models with trans-omics biomarkers for early-stage lung adenocarcinoma (LUAD). We performed integrative analysis of clinical information, DNA methylation, and gene expression data using 825 early ...
Alolga, Raphael N.,, Bjaanæs, Maria Moksnes,, Chen, Chao,, Chen, Feng,, Christiani, David C.,, Dong, Xuesi,, Duan, Weiwei,, Esteller, Manel,, Fleischer, Thomas,, He, Jieyu,, Helland, Åslaug,, Karlsson, Anna,, Lai, Linjing,, Lin, Lijuan,, Lund University., Planck, Maria,, Salama, Moran,, Shafer, Andrea,, Shen, Sipeng,, Staaf, Johan,, Su, Li,, Wang, Rui,, Wei, Yongyue,, You, Dongfang,, Zhang, Ruyang,, Zhao, Yang,, Zhu, Ying,   +26 more
core   +1 more source

The study of phosphate transporter NAPI2B expression in different histological types of epithelial ovarian cancer.

Experimental oncology, 2009
The identification of markers that are specifically expressed by different histological types of epithelial ovarian cancer (EOC) may lead to the development of novel and more specific diagnostic and therapeutic strategies. Sodium-dependent phosphate transporter NaPi2b (or MX35 ovarian cancer antigen) is a novel perspective marker of EOC.
Gryshkova, V., Goncharuk, I., Gurtovyy, V., Khozhayenko, Yu., Nespryadko, S., Vorobjova, L., Usenko, V., Gout, I., Filonenko, V., Kiyamova, R.   +9 more
openaire   +2 more sources

Drogas Conjugadas com Anticorpos no Tratamento do Câncer: Uma Revisão de Literatura [PDF]

Introdução: A imunoterapia oncológica tem se consolidado como uma das principais abordagens terapêuticas no tratamento do câncer. Entre seus avanços, destacam-se os anticorpos conjugados a drogas (ADCs), que combinam especificidade molecular à ação ...
Alonso, Matheus Felipe, Borges, Larissa Ribeiro Soares, Donzelli, Renato Vieira, Kuranishi, Maria Eduarda, Medeiros, Caylani Tatiara Martins de, Meirelles, Izadora Cruz, Milan, Nycollas Russo, Sant'Ana, Paula Grippa, Silva, Maria Eduarda Peripolli da   +8 more
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Immunohistochemical analysis of NaPi2b protein (MX35 antigen) expression and subcellular localization in human normal and cancer tissues.

Experimental oncology, 2012
To study the expression profile of the NaPi2b protein and its localization in breast, ovarian and lung cancer cells in relation to normal tissues adjacent to tumor.Immunohistochemical analysis with monoclonal antibody MX35 was applied for investigation of NaPi2b protein expression in breast, lung and ovarian carcinomas.
Kiyamova, R., Shyian, M., Lyzogubov, V.V., Usenko, V.S., Gout, T., Filonenko, V.   +5 more
openaire   +2 more sources