Results 71 to 80 of about 15,506 (210)
Healthcare Burden and Productivity Loss Due to Narcolepsy in Sweden
Clocks & SleepBackground: Narcolepsy impacts both patients and society, yet there is limited data on its socioeconomic consequences. Methods: This retrospective longitudinal cohort study used pseudonymized patient-level data from Swedish registers and included ...
Anna Giertz +5 more
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eNeurologicalSci, 2018 We report a case of probable encephalitis presenting as narcolepsy with cataplexy, but with cyclical exacerbation and cognitive difficulties. Our patient continued to worsen despite treatment for narcolepsy and later was thought to have an immune ...
Rafer Willenberg, Jonathan D. Bui
doaj +1 more source
The neurobiology of narcolepsy [PDF]
Trends in Neurosciences, 1991 Narcolepsy is characterized by excessive sleepiness and abnormal manifestations of rapid eye movement (REM) sleep. Neurochemical studies of human and canine narcolepsy have demonstrated disturbed monoaminergic and cholinergic function and suggest that deficits of noradrenaline availability in specific brain regions may account for much of its ...
openaire +3 more sources
Prisoners of the Body: The Link Between Interoception and Sleep Paralysis
Journal of Sleep Research, EarlyView.ABSTRACT Sleep paralysis (SP) is a REM sleep parasomnia characterized by transient motor paralysis during sleep onset or awakening. It is a terrifying experience often accompanied by vivid hallucinations. Although it is classically linked to narcolepsy, isolated SP in healthy individuals offers a valuable model to investigate the interaction between ...
Giuseppe Forte +3 more
wiley +1 more source
Journal of Sleep Research, EarlyView.ABSTRACT Narcolepsy is classified as type 1 (NT1) or type 2 (NT2) mainly according to hypocretin deficiency rather than cataplexy. While CRH neuron loss in the PVN has been described in NT1, it remains unclear whether similar changes occur in narcolepsy without cataplexy.
Ling Shan +5 more
wiley +1 more source
The Development of the European Sleep Questionnaire A New Patient‐Reported Outcome Measure
Journal of Sleep Research, EarlyView.ABSTRACT Sleep medicine relies on patient‐reported outcome measures (PROMs) to complement clinical interviews and objective sleep tests. Available sleep questionnaires focus on isolated symptoms or single disorders, limiting their ability to capture the complexity of sleep conditions. Also, many PROMs remain poorly validated.
Dirk A. Pevernagie +20 more
wiley +1 more source
Neuropsychiatric Disease and Treatment, 2011 Gbolagade Sunmaila Akintomide1, Hugh Rickards21Department of Neuropsychiatry, University of Birmingham, 2Department of Neuropsychiatry, The Barberry, Edgbaston, Birmingham, UKAbstract: Narcolepsy is a lifelong sleep disorder characterized by a classic ...
Akintomide GS, Rickards H
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Narcolepsy in childhood and adolescence
Sleep Science, 2012 The present review article discusses the most important aspects of narcolepsy in children. The main objective of this review is to describe the clinical and laboratory characteristics of narcolepsy in patients within a targeted age range and to discuss ...
Fernando M. S. Coelho +8 more
doaj +1 more source
Journal of Sleep Research, EarlyView.ABSTRACT Machine learning provides a powerful tool to capture complex, nonlinear patterns in biomedical data and enhance precision risk stratification. In this study, we applied a multilayer perceptron (MLP) framework to classify Framingham Risk Score–based cardiovascular risk categories in patients with obstructive sleep apnea (OSA).
Feng Zhao +10 more
wiley +1 more source
Update on the treatment of narcolepsy: clinical efficacy of pitolisant
Nature and Science of Sleep, 2017 Michael W Calik1,2 1Department of Biobehavioral Health Science, 2Center for Narcolepsy, Sleep and Health Research, University of Illinois at Chicago, Chicago, IL, United States Abstract: Narcolepsy is a neurological disease that affects 1 in 2,000 ...
Calik MW
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