Results 51 to 60 of about 21,657 (219)

Global estimates of vaccine-associated narcolepsy from 1967 to 2023

open access: yesScientific Reports
Regional evidence on the signal detection between narcolepsy and vaccines is scarcely available and insufficiently understood, thus impeding a comprehensive understanding of this relationship on a global scale. Therefore, this study aimed to evaluate the
Yi Deun Jeong   +12 more
doaj   +1 more source

Cerebrospinal fluid orexin testing in Australians with narcolepsy type 1

open access: yesInternal Medicine Journal, EarlyView.
Abstract A clinical diagnosis of narcolepsy type 1 can be challenging, particularly in relation to cataplexy. Despite its specificity, cerebrospinal fluid (CSF) orexin testing is under‐utilised in Australasia. We describe the use of CSF orexin testing in 15 clinically indicated patients from two sleep centres, highlighting its utility in the ...
Mario Fernando   +8 more
wiley   +1 more source

A Case of Secondary Narcolepsy Presenting with Obstructive Sleep Apnea Symptoms

open access: yesTürk Uyku Tıbbı Dergisi, 2016
Obstructive sleep apnea syndrome (OSAS) and narcolepsy are two diseases causing excessive daytime sleepiness (EDS). As they are often confused, these two disorders can also coexist.
Sebahat Genç   +4 more
doaj   +1 more source

Metrology of two wearable sleep trackers against polysomnography in patients with sleep complaints

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep trackers are used widely by patients with sleep complaints, however their metrological validation is often poor and relies on healthy subjects. We assessed the metrological validity of two commercially available sleep trackers (Withings Activité/Fitbit Alta HR) through a prospective observational monocentric study, in adult patients ...
Justine Frija   +11 more
wiley   +1 more source

Narcolepsy and rapid eye movement sleep

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini   +4 more
wiley   +1 more source

Ageing‐related modification of sleep and breathing in orexin‐knockout narcoleptic mice

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Narcolepsy type‐1 (NT1) is a lifelong sleep disease, characterised by impairment of the orexinergic system, with a typical onset during adolescence and young adulthood. Since the wake–sleep cycle physiologically changes with ageing, this study aims to compare sleep patterns between orexin‐knockout (KO) and wild type (WT) control mice at ...
Stefano Bastianini   +7 more
wiley   +1 more source

Relationship between T-cell receptor α gene polymorphisms and symptomatic differences in patients with narcolepsy type 1

open access: yesChinese Medical Journal, 2019
. Background:. Recent genome-wide association studies have identified an important role of T-cell receptor α (TRA) gene in the development of narcolepsy type 1.
Hui Ouyang   +6 more
doaj   +1 more source

Profiling the sleep architecture of ageing adults using a seven‐state continuous‐time Markov model

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep is a complex biological process regulated by networks of neurons and environmental factors. As one falls asleep, neurotransmitters from sleep–wake regulating neurones work in synergy to control the switching of different sleep states throughout the night. As sleep disorders or underlying neuropathology can manifest as irregular switching,
Jonathon Jacobs   +3 more
wiley   +1 more source

Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleepiness and apathy are often reported in patients with normal pressure hydrocephalus. However, research on outcomes after shunt surgery has mainly focused on the classical triad symptoms, that is, gait, cognition, and bladder dysfunction. This study aimed to describe the effects of shunt treatment on excessive daytime sleepiness and whether ...
Simon Lidén   +4 more
wiley   +1 more source

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