Results 51 to 60 of about 38,442 (298)

Narcolepsy with cataplexy in monozygotic twins

open access: yesSleep Science, 2014
Introduction: This paper describes narcolepsy with cataplexy in two monozygotic twin sisters. Objective: To clinically illustrate the involvement of neurological, genetic and immunologic systems in narcolepsy.
Leonardo I. Goulart   +4 more
doaj   +1 more source

Persistence of poor sleep predicts the severity of the clinical condition after 6months of standard treatment in patients with eating disorders [PDF]

open access: yes, 2015
Clinical evidence suggests that eating disorder (ED) patients experience poor sleep even if they rarely complain of it. However, direct empirical evidence supporting this relationship is still sparse.
Battagliese, Gemma   +3 more
core   +1 more source

Narcolepsy in early childhood: a case report and a Mini review

open access: yesFrontiers in Pediatrics
Narcolepsy is a sleep-wake disorder with an onset commonly seen in individuals aged 10–30 years. Due to various reasons, the diagnosis of narcolepsy often experiences a delay of at least ten years.
Guorui Liu   +12 more
doaj   +1 more source

Neuroimaging in Narcolepsy [PDF]

open access: yesSleep Medicine, 2010
Narcolepsy is a chronic neurological disorder, has no specific cause, and is characterized by excessive daytime sleepiness and uncontrollable sleep attacks. In case of strong emotions such as laughter, anger or joy, a cataplexy (sudden loss of muscle tone, lasting for a short period of time) may occur (1, 2).
Hakyemez, BAHATTİN   +5 more
openaire   +6 more sources

Recursive Partitioning Analysis of Fractional Low-Frequency Fluctuations in Narcolepsy With Cataplexy

open access: yesFrontiers in Neurology, 2018
Objective: To identify narcolepsy related regional brain activity alterations compared with matched healthy controls. To determine whether these changes can be used to distinguish narcolepsy from healthy controls by recursive partitioning analysis (RPA ...
Xiao Fulong   +6 more
doaj   +1 more source

Connexin-dependent neuroglial networking as a new therapeutic target [PDF]

open access: yes, 2017
Astrocytes and neurons dynamically interact during physiological processes, and it is now widely accepted that they are both organized in plastic and tightly regulated networks.
Christian C. Naus   +5 more
core   +2 more sources

Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke   +5 more
wiley   +1 more source

Narcolepsy: the impact of aging, hypocretin deficiency, and years of formal education in olfactory function and abdominal obesity

open access: yesArquivos de Neuro-Psiquiatria, 2021
Background: Narcolepsy is a disease resulting from the loss of hypocretin-producing cells or other dysfunctions of the hypocretinergic system. In addition to sleep disorders, affected patients may experience increased weight gain, olfactory changes, and ...
Giselle de Martin Truzzi   +3 more
doaj   +1 more source

Ullanlinna Narcolepsy Scale in diagnosis of narcolepsy [PDF]

open access: yesSleep, 2018
To validate Ullanlinna Narcolepsy Scale (UNS) as a screening tool for narcolepsy in a clinical population and to compare it with Swiss Narcolepsy Scale (SNS) and Epworth Sleepiness Scale (ESS).UNS questionnaires of 267 participants visiting Helsinki Sleep Clinic were analyzed.
Tomi Sarkanen   +2 more
openaire   +3 more sources

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

open access: yesAnnals of Neurology, EarlyView.
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa   +6 more
wiley   +1 more source

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