Results 51 to 60 of about 15,506 (210)

Narcolepsy: an interface among neurology, immunology, sleep, and genetics

Arquivos de Neuro-Psiquiatria
Narcolepsy is a primary disorder of the central nervous system resulting from genetic, environmental, and immunological interactions defined as excessive daytime sleepiness plus cataplexy, hallucinations, sleep paralysis, and sleep fragmentation.
Fernando Morgadinho Santos Coelho
doaj   +1 more source

Metrology of two wearable sleep trackers against polysomnography in patients with sleep complaints

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep trackers are used widely by patients with sleep complaints, however their metrological validation is often poor and relies on healthy subjects. We assessed the metrological validity of two commercially available sleep trackers (Withings Activité/Fitbit Alta HR) through a prospective observational monocentric study, in adult patients ...
Justine Frija, Jimmy Mullaert, Laure Abensur Vuillaume, Mathieu Grajoszex, Ruben Wanono, Hélène Benzaquen, Fedja Kerzabi, Pierre Alexis Geoffroy, Boris Matrot, Théo Trioux, Thomas Penzel, Marie‐Pia d'Ortho   +11 more
wiley   +1 more source

Symptomatic Narcolepsy and Generalized Seizures Following Surgery for Rathke’s Cleft Cyst [PDF]

Sleep Medicine Research, 2014
Symptomatic narcolepsy is a rare disorder caused by other underlying neurological disorders. One of the most frequent causes for symptomatic narcolepsy is brain tumors, usually in the region of the third ventricle and the diencephalon.
On-Hwa Ryu, Han Uk Ryu, Sang-Ahm Lee
doaj   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Central disorders of hypersomnolence in children and adults: A comparative study from South India

Annals of Indian Academy of Neurology, 2019
Background: Narcolepsy and idiopathic hypersomnolence (IHS) are rare disorders. In Western populations, the reported prevalence of narcolepsy is 0.02%–0.05%. In Indian subcontinent, there are few reports on narcolepsy and none on IHS so far.
Madhukar Trivedi, Sapna Erat Sreedharan, Shana N Nair, C A Anees, J P Unnikrishnan, P S Sarma, Ashalatha Radhakrishnan   +6 more
doaj   +1 more source

Ageing‐related modification of sleep and breathing in orexin‐knockout narcoleptic mice

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Narcolepsy type‐1 (NT1) is a lifelong sleep disease, characterised by impairment of the orexinergic system, with a typical onset during adolescence and young adulthood. Since the wake–sleep cycle physiologically changes with ageing, this study aims to compare sleep patterns between orexin‐knockout (KO) and wild type (WT) control mice at ...
Stefano Bastianini, Sara Alvente, Chiara Berteotti, Viviana Lo Martire, Gabriele Matteoli, Elena Miglioranza, Alessandro Silvani, Giovanna Zoccoli   +7 more
wiley   +1 more source

Global estimates of vaccine-associated narcolepsy from 1967 to 2023

Scientific Reports
Regional evidence on the signal detection between narcolepsy and vaccines is scarcely available and insufficiently understood, thus impeding a comprehensive understanding of this relationship on a global scale. Therefore, this study aimed to evaluate the
Yi Deun Jeong, Hyesu Jo, Yesol Yim, Sooji Lee, Jaeyu Park, Jinseok Lee, Jiseung Kang, Louis Jacob, Lee Smith, Masoud Rahmati, Guillermo F. López Sánchez, Hayeon Lee, Dong Keon Yon   +12 more
doaj   +1 more source

Selegiline in Narcolepsy [PDF]

Sleep, 1986
We examined the effect of the specific monoamine oxidase-B (MAO-B) inhibitor selegiline (deprenyl, Eldepryl), 20-30 mg p.o. daily, in 21 subjects with the narcoleptic syndrome for 4 weeks. Selegiline was compared to no treatment (7 subjects) or conventional central stimulant drugs, including dexamphetamine or mazindol (14 subjects).
S E, Roselaar, N, Langdon, C B, Lock, P, Jenner, J D, Parkes   +4 more
openaire   +2 more sources

Profiling the sleep architecture of ageing adults using a seven‐state continuous‐time Markov model

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep is a complex biological process regulated by networks of neurons and environmental factors. As one falls asleep, neurotransmitters from sleep–wake regulating neurones work in synergy to control the switching of different sleep states throughout the night. As sleep disorders or underlying neuropathology can manifest as irregular switching,
Jonathon Jacobs, Caitlin E. Martin, Bernard Fuemmeler, Shanshan Chen   +3 more
wiley   +1 more source

Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleepiness and apathy are often reported in patients with normal pressure hydrocephalus. However, research on outcomes after shunt surgery has mainly focused on the classical triad symptoms, that is, gait, cognition, and bladder dysfunction. This study aimed to describe the effects of shunt treatment on excessive daytime sleepiness and whether ...
Simon Lidén, Anna Lindam, Dan Farahmand, Anne‐Marie Landtblom, Katarina Laurell   +4 more
wiley   +1 more source