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Recently Approved and Upcoming Treatments for Narcolepsy
CNS Drugs, 2020 Narcolepsy is a chronic, disabling neurologic disorder characterised by excessive daytime sleepiness (EDS) and, in up to 60% of patients, cataplexy. Treatments for narcolepsy are aimed at improving wakefulness (e.g.
M. Thorpy
semanticscholar +1 more source
Scientific Reports, 2018 The pathophysiology of rapid eye movement sleep behavior disorder (RBD) associated with narcolepsy type 1 (NT1) is still poorly understood, potentially distinct from idiopathic RBD (iRBD), but may share affected common pathways.
Lucie Barateau +7 more
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Narcolepsy and anxiety. Is this association possible?
European Psychiatry, 2021 Introduction Excessive daytime sleepiness, hypnagogic-hypnopompic hallucinations, sleep paralysis, and cataplexy are symptoms associated with narcolepsy. It is not uncommon to occur co-morbidly between narcolepsy and psychiatric disorders.
G.M. Ruiz Martinez +2 more
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A practical guide to the pharmacological and behavioral therapy of Narcolepsy
Neurotherapeutics, 2021 Narcolepsy is a rare, chronic, and disabling central nervous system hypersomnia; two forms can be recognized: narcolepsy type 1 (NT1) and narcolepsy type 2 (NT2).
C. Franceschini +3 more
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Clinical pearls for the treatment of narcolepsy [PDF]
Mental Health ClinicianNarcolepsy is a chronic neurologic state in which patients experience an irrepressible need to sleep or lapses into sleep. The hallmark symptom of narcolepsy is excessive daytime sleepiness, but patients may also experience other symptoms, such as ...
Marilyn N. Bulloch, PharmD, BCPS, FCCM, SPP +1 more
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Health‐related quality of life in narcolepsy: A systematic review and meta‐analysis
Journal of Sleep Research, 2021 To date, there has been no systematic analysis of the literature regarding health‐related quality of life in narcolepsy. This systematic review aimed to examine the impact of narcolepsy on health‐related quality of life, measured through standardised ...
R. Tadrous +3 more
semanticscholar +1 more source
Misdiagnosis of narcolepsy [PDF]
Sleep and Breathing, 2016 Narcolepsy is a chronic primary sleep disorder, characterized by excessive daytime sleepiness and sleep dysfunction with or without cataplexy. Narcolepsy is uncommon, with a low prevalence rate which makes it difficult to diagnose definitively without a complex series of tests and a detailed history.
Dunne, Laura +4 more
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Body Weight and Metabolic Rate Changes in Narcolepsy: Current Knowledge and Future Directions
Metabolites, 2022 Narcolepsy is a known auto-immune disease that presents mainly in the teenage years with irresistible sleep attacks. Patients with narcolepsy, especially NT1, have been found to have a high prevalence of obesity and other metabolic derangements.
Hamza O. Dhafar, Ahmed S. BaHammam
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Analysis of thyroid function and related factors in narcolepsy patients
Scientific Reports, 2023 The loss of hypocretin is thought to be the main pathophysiological mechanism of narcolepsy. There is strong evidence that hypocretin is related to the regulation of endocrine functions and depression.
Hongli Wang, Mingrui Jia
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Data-Driven Research Needed to Ensure Timely Access to New Narcolepsy Treatments [PDF]
Dr Helen Strongman shares her perspective on access to new narcolepsy treatments – as a person with narcolepsy, trustee and director at Narcolepsy UK, and health data ...
Strongman, Helen
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