Results 21 to 30 of about 21,657 (219)

Quickly diagnosed and treated prepubertal Type 1 narcolepsy case

Psychiatry and Clinical Psychopharmacology, 2018
Excessive daytime sleepiness, cataplexy, sleep paralysis, and hypnagogic hallucination are the classic tetrad of narcolepsy. It has been shown that narcolepsy, a chronic and disabling disease, starts in childhood and adolescence rather than adulthood ...
Fikret Poyraz Çökmüş, Orkun Aydın, Didem Sücüllüoğlu Dikici, Şermin Yalın Sapmaz   +3 more
doaj   +1 more source

iSPHYNCS: Unsupervised Clustering in Questionnaires and Metadata Reveals Distinct Subtypes in the Narcolepsy Borderland.

Journal of Sleep Research, EarlyView.
Study overview and clustering results in the iSPHYNCS cohort. Participant demographics are summarized in a baseline table. Questionnaire data and metadata were processed through an unsupervised clustering pipeline. A Sankey plot illustrates individual assignment across clusters by diagnostic group.
Rafael Morand, Livia Fregolente, Julia van der Meer, Elena Wenz, Annina Helmy, Lorenzo Brigato, D. Warncke Jan, Kseniia Zub, Ramin Khatami, Zhongxing Zhang, von Manitius, Sigrid, Silvia Miano, Jens G Acker, Mathias Strub, Ulf Kallweit, Gert Jan Lammers, Athina Tzovara, Claudio L. A. Bassetti, Stavroula Mougiakakou, Markus H. Schmidt   +19 more
openalex   +2 more sources

The Prevalence and Characteristics of Primary Headache and Dream-Enacting Behaviour in Japanese Patients with Narcolepsy or Idiopathic Hypersomnia: A Multi-Centre Cross-Sectional Study. [PDF]

PLoS ONE, 2015
Because the prevalence and characteristics of primary headache have yet to be thoroughly studied in patients with hypersomnia disorders, including narcolepsy and idiopathic hypersomnia, we examined these parameters in the Japanese population.In a ...
Keisuke Suzuki, Masayuki Miyamoto, Tomoyuki Miyamoto, Yuichi Inoue, Kentaro Matsui, Shingo Nishida, Kenichi Hayashida, Akira Usui, Yoichiro Ueki, Masaki Nakamura, Momoyo Murata, Ayaka Numao, Yuji Watanabe, Shiho Suzuki, Koichi Hirata   +14 more
doaj   +1 more source

Narcolepsy Syndrome in a Patient with Multiple Sclerosis

Türk Uyku Tıbbı Dergisi, 2014
Narcolepsy syndrome is characterized by excessive daytime sleepiness with or without cataplexy. In addition to excessive daytime sleepiness and cataplexy, other symptoms related to REM-sleep such as disturbed night sleep, sleep paralysis and hypnopompic ...
Deniz Yerdelen, Gülçin Benbir, Uğur Uygunoğlu, Aksel Siva, Derya Karadeniz   +4 more
doaj   +1 more source

Narcolepsy in early childhood: a case report and a Mini review

Frontiers in Pediatrics
Narcolepsy is a sleep-wake disorder with an onset commonly seen in individuals aged 10–30 years. Due to various reasons, the diagnosis of narcolepsy often experiences a delay of at least ten years.
Guorui Liu, Guorui Liu, Guanxiong Li, Yihao Wang, Ming Yin, Wen Pan, Yu Zhao, Shigeng Gao, Peiqi Shi, Jing Wen, Xiao Pan, Yajing Wang, Yanfei Zhang   +12 more
doaj   +1 more source

Narcolepsy with cataplexy in monozygotic twins

Sleep Science, 2014
Introduction: This paper describes narcolepsy with cataplexy in two monozygotic twin sisters. Objective: To clinically illustrate the involvement of neurological, genetic and immunologic systems in narcolepsy.
Leonardo I. Goulart, Mário Pedrazolli, Alexandre H. Martori, Alan Eckeli, Heidi H. Sander   +4 more
doaj   +1 more source

Recursive Partitioning Analysis of Fractional Low-Frequency Fluctuations in Narcolepsy With Cataplexy

Frontiers in Neurology, 2018
Objective: To identify narcolepsy related regional brain activity alterations compared with matched healthy controls. To determine whether these changes can be used to distinguish narcolepsy from healthy controls by recursive partitioning analysis (RPA ...
Xiao Fulong, Lu Chao, Zhao Dianjiang, Zou Qihong, Zhang Wei, Zhang Jun, Han Fang   +6 more
doaj   +1 more source

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

Annals of Neurology, EarlyView.
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa, Aurosman Pappus Sahu, David B. Rye, Lynn Marie Trotti, Irina A. Elcheva, Vladimir S. Spiegelman, James R. Connor   +6 more
wiley   +1 more source

Bidirectional sleep‐seizure interactions and orexin in a mouse model of tuberous sclerosis complex‐related epilepsy

Epilepsia, EarlyView.
Abstract Objective A strong bidirectional relationship exists between epilepsy and sleep, with seizures often occurring more frequently in sleep and, in turn, sleep being disrupted by seizures. However, the mechanistic basis of seizure–sleep interactions is poorly understood.
Nicholas R. Rensing, Lirong Han, Dongjun Guo, Thomas J. Foutz, Michael Wong   +4 more
wiley   +1 more source

Narcolepsy: the impact of aging, hypocretin deficiency, and years of formal education in olfactory function and abdominal obesity

Arquivos de Neuro-Psiquiatria, 2021
Background: Narcolepsy is a disease resulting from the loss of hypocretin-producing cells or other dysfunctions of the hypocretinergic system. In addition to sleep disorders, affected patients may experience increased weight gain, olfactory changes, and ...
Giselle de Martin Truzzi, Maria Fernanda Naufel, Sergio Tufik, Fernando Morgadinho Coelho   +3 more
doaj   +1 more source