Results 1 to 10 of about 13,366 (218)
Studies on the Specificity of Narcotic Antagonists [PDF]
Anesthesiology, 1965 Experiments with five narcotics, (morphine 0.3 mg./kg., oxymorphone 20 μg./kg., levorphan 50 μg./kg., meperidine 1.5 μg./kg. and fentanyl 1.5 μ./kg.) and three narcotic antagonists (nalorphine 150 μg./kg., naloxone 5 μg./kg., and levallorphan 20 μg./kg.
Francis F. Foldes +4 more
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Use of narcotic antagonists in anaesthesia. [PDF]
British Journal of Clinical Pharmacology, 1979 1 The introduction of morphine antagonists into anaesthesiology has aroused great scientific interest, increased our knowledge of analgesia, and opened new frontiers for therapeutics. 2 The advantages and disadvantages of these compounds are described and assessed.
Castro João Jácome de
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Human pharmacology of narcotic antagonists. [PDF]
British Journal of Clinical Pharmacology, 1979 1 Human studies at the Addiction Research Center enable narcotic antagonists to be classified into three subgroups: (1) nalorphine‐like agents; (2) pure antagonists; and (3) morphine‐like agents. 2 Six narcotic antagonists (pentazocine, nalbuphine, cyclazocine, butorphanol, propiram and buprenorphine) developed in recent years seem to have a lesser ...
DR Jasinski
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THE EFFECT OF NARCOTIC AND NARCOTIC-ANTAGONIST DRUGS IN THE NEWBORN RABBIT
British Journal of Anaesthesia, 1976 The newborn rabbit responds to acute anoxia, as a result of breathing nitrogen, with successive periods of dyspnoea, primary apnoea, gasping and terminal apnoea. Pethidine caused an increase in the period of primary apnoea and a decrease in the duration and rate of gasping.
G.W. STEPHEN +2 more
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Book Review: Narcotics and Narcotic Antagonists [PDF]
Proceedings of the Royal Society of Medicine, 1965 Laurence Després
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NARCOTIC–NARCOTIC ANTAGONIST MIXTURES [PDF]
Anesthesiology, 1961 Jane Telford, Arthur S. Keats
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The Combined Use of Narcotics and Narcotic Antagonists for Premedication [PDF]
Anesthesiology, 1959 HENRY M. BRUNN +3 more
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Antipruritic Effect of Nalbuphine, a Kappa Opioid Receptor Agonist, in Mice: A Pan Antipruritic
Molecules, 2021 Antipruritic effects of kappa opioid receptor (KOR) agonists have been shown in rodent models of acute and chronic scratching (itchlike behavior). Three KOR agonists, nalfurafine, difelikefalin, and nalbuphine, are in clinical studies for antipruritic ...
Saadet Inan, Nae J. Dun, Alan Cowan
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Pharmaceutics, 2022 Pentazocine (PTZ), a narcotic-antagonist analgesic, has been extensively used in the treatment of initial carcinogenic or postoperative pain. Hepatic first-pass metabolism results in low oral bioavailability and high dose wastage.
Zaheer Ullah Khan +10 more
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Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism. [PDF]
PLoS ONE, 2013 Novel classes of pain-relieving molecules are needed to fill the void between non-steroidal anti-inflammatory agents and narcotics. We have recently shown that intraplantar administration of sphingosine 1-phosphate (S1P) in rats causes peripheral ...
Amanda Finley +5 more
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