Results 1 to 10 of about 558,994 (238)

DFT study of species derived from the narcotic antagonist naloxone

Biointerface Research in Applied Chemistry, 2020
The functional hybrid B3LYP and the 6-31G* basis set have been employed to study the theoretical structures of free base, cationic and hydrochloride species of naloxone in gas phase and in aqueous solution.
M. Marquez, Silvia Antonia Brandán, S Brandn, R Rudyk, S Brandn, D Romani, S Brandn, M Iramain, A Ledesma, S Brandn, S Brandn, R Rudyk, M Checa, K Guzzetti, M Iramain, S Brandn, R Rudyk, M Checa, C Cataln, S Brandn, Structural, M Manzur, S Brandn, S Brandn, M Iramain, L Davies, S Brandn, Ftir, J Kausteklis, V Aleksa, M Iramain, S Brandn, M Iramain, L Davies, S Brandn, J Kausteklis, V Aleksa, M Iramain, S Brandn, M Iramain, L Davies, S Brandn, M Iramain, A Ledesma, S Brandn, M Iramain, S Brandn, M Mrquez, M Iramain, S Brandn, I Karle, D Wermeling, C Pert, G Pasternak, S Snyder, C Pert, S Snyder, C Lee, W Yang, R Parr, A Becke, S Miertus, E Scrocco, J Tomasi, J Tomasi, J Persico, A Marenich, C Cramer, D Truhlar, P Pulay, G Fogarasi, G Pongor, J Boggs, A Vargha, G Rauhut, P Pulay, T Sundius, R Paar, R Pearson, M Minteguiaga, E Dellacassa, M Iramain, C Cataln, S Brandn, B Brandn, S Issaoui, N Roisnel, T Marouani, H Synthesis, S Gatfaoui, N Issaoui, S Brandn, T Roisnel, H Marouani, M Minteguiaga, E Dellacassa, M Iramain, C Cataln, S Brandn, Ft-Ir   +99 more
semanticscholar   +2 more sources

Quantitative studies on the antagonism by naloxone of some narcotic and narcotic‐antagonist analgesics [PDF]

British Journal of Pharmacology, 1970
S. Smits, A. Takemori
semanticscholar   +2 more sources

Failure of narcotic antagonist to alter electroacupuncture modification of halothane anaesthesia in the dog [PDF]

Canadian Anaesthetists' Society journal, 1982
A. L. Tay, C. Tseng, N. Pace, K. C. Wong, B. Hong-Goka   +4 more
semanticscholar   +2 more sources

Antipruritic Effect of Nalbuphine, a Kappa Opioid Receptor Agonist, in Mice: A Pan Antipruritic

Molecules, 2021
Antipruritic effects of kappa opioid receptor (KOR) agonists have been shown in rodent models of acute and chronic scratching (itchlike behavior). Three KOR agonists, nalfurafine, difelikefalin, and nalbuphine, are in clinical studies for antipruritic ...
Saadet Inan, Nae J. Dun, Alan Cowan
doaj   +1 more source

Physicochemical Characterizations and Pharmacokinetic Evaluation of Pentazocine Solid Lipid Nanoparticles against Inflammatory Pain Model

Pharmaceutics, 2022
Pentazocine (PTZ), a narcotic-antagonist analgesic, has been extensively used in the treatment of initial carcinogenic or postoperative pain. Hepatic first-pass metabolism results in low oral bioavailability and high dose wastage.
Zaheer Ullah Khan, Anam Razzaq, Ahsan Khan, Naeem Ur Rehman, Hira Khan, Taous Khan, Ashraf Ullah Khan, Norah A. Althobaiti, Farid Menaa, Haroon Iqbal, Naveed Ullah Khan   +10 more
doaj   +1 more source

Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism. [PDF]

PLoS ONE, 2013
Novel classes of pain-relieving molecules are needed to fill the void between non-steroidal anti-inflammatory agents and narcotics. We have recently shown that intraplantar administration of sphingosine 1-phosphate (S1P) in rats causes peripheral ...
Amanda Finley, Zhoumou Chen, Emanuela Esposito, Salvatore Cuzzocrea, Roger Sabbadini, Daniela Salvemini   +5 more
doaj   +1 more source

Sexual differentiation of the luteinizing hormone response of neonatal rats to the narcotic antagonist naloxone: critical role of estrogen receptors. [PDF]

Biology of Reproduction, 1988
O. Almeida, R. Schulz
semanticscholar   +2 more sources

Effects of Loperamide on Mechanical Allodynia Induced by Herpes Simplex Virus Type-1 in Mice

Journal of Pharmacological Sciences, 2007
In the present study, we investigated whether the peripherally acting µ-opioid receptor agonist loperamide would inhibit allodynia in the non-inflamed dermatome of mice with herpetic pain.
Atsushi Sasaki, Yasutaka Nakashima, Ichiro Takasaki, Tsugunobu Andoh, Kimiyasu Shiraki, Yasushi Kuraishi   +5 more
doaj   +1 more source

Medical expulsive therapy

Indian Journal of Urology, 2014
The objective of this review article is to present the current literature on medical expulsive therapy (MET) and help guide practitioners in the appropriate use of MET for treatment of stone disease.
Kyle D Wood, Ilya Gorbachinsky, Jorge Gutierrez   +2 more
doaj   +1 more source

Comparative study of intrathecal dexmedetomidine, fentanyl, and magnesium sulfate as adjuvants to 0.5% hyperbaric bupivacaine for knee arthroscopic surgeries

Al-Azhar Assiut Medical Journal
Background and aim Fentanyl is one of the short-acting narcotic analgesics with potent morphine-like action. Dexmedetomidine is a highly selective α2 adrenergic agonist which has been used for premedication and as an adjunct to general anesthesia.
Osama H. Ahmed, Mahmoud A. Abdelsalam, Mohamed A. Makhlouf   +2 more
doaj   +1 more source