Results 101 to 110 of about 554,314 (294)

Assessing agroecosystem resilience in annual cropping systems with ecometabolomics

open access: yesAgrosystems, Geosciences &Environment, Volume 8, Issue 2, June 2025.
Abstract Plant ecometabolomics is a growing field of study that allows broader understanding of the metabolomic dynamics within and between plants and their ecosystem. Plants constantly respond to environmental cues, producing plant secondary metabolites (PSMs) to communicate with and adapt to their ever‐changing ecosystems.
Andrea K. Clemensen   +6 more
wiley   +1 more source

Ring C substituted 14-hydroxymorphinans and isomorphinans as narcotic antagonists [PDF]

open access: bronze, 1976
Marcel Ménard   +4 more
openalex   +1 more source

Drug‐Event Pairs as Indicators for the Detection of Adverse Drug Reactions during Hospitalization in Routinely Collected Electronic Data Sources

open access: yesClinical Pharmacology &Therapeutics, Volume 117, Issue 6, Page 1811-1819, June 2025.
Adverse drug reactions (ADRs) are a common cause of morbidity and mortality in hospitalized patients. Identification of ADRs in clinical practice, surveillance and research is essential to prevent further harm. The aim of this study was to assess the likelihood of drugs contributing to clinically important inpatient adverse events, in order to provide ...
Anna Maria Wermund   +5 more
wiley   +1 more source

The antagonism of narcotics by L-3-Hydroxy-N-Allylmorphinan (Levallorphan) L-3-Hydroxy-N-Propargylmorphinan (Propallorophan) and 2,4-Diamino-5-Phenylthiazole (Daptazole) [PDF]

open access: yes, 1957
Thesis (Ph.D.)--Boston UniversityIn this study, propallorphan (a-3-hydroxy-N-propargylmorphina.n, Ro-1-7780) was found to be a potent alphaprodine to alphaprodine in both dog and man.
Megirian, Robert
core  

Assessing Semiregional Cerebral Oxygen Consumption (CMRO2) in Preterm Neonates: A Quantitative MRI Cohort Study With Exploratory Analysis of Respiratory Support

open access: yesNMR in Biomedicine, Volume 38, Issue 6, June 2025.
This study presents a novel multimodal MRI approach to measure cerebral blood flow (CBF) and oxygen metabolism (CMRO2) in preterm infants. Exploratory findings suggest noninvasive respiratory support is associated with higher CBF and CMRO2, highlighting its potential impact on neonatal brain oxygenation and development.
Chen Shuang Zhu   +5 more
wiley   +1 more source

Outcome and process frames: Strategic renewal and capability reprioritization at the Federal Bureau of Investigation

open access: yesStrategic Management Journal, Volume 46, Issue 6, Page 1325-1362, June 2025.
Abstract Research Summary Framing is critical for leaders who must build support for strategic renewal. While research has concentrated on renewal that replaces one set of capabilities with another, we explore a distinctive challenge: how leaders persuade stakeholders to endorse the reprioritization of resources toward a capability set that must ...
Ryan Raffaelli   +3 more
wiley   +1 more source

A Background of the Opioid Epidemic and Its Relationship to the Medicaid Expansion [PDF]

open access: yes, 2019
Despite the recent increase in public awareness of the opioid epidemic, the background of this epidemic is still disappointingly unknown to the public.
Jang, Er Yearn
core   +2 more sources

Spontaneous and pharmacologically induced hypothermia protect mice against endotoxic shock

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 12, Page 2621-2641, June 2025.
Background and Purpose Despite the well‐known occurrence of hypothermia during sepsis, its underlying biological nature and adaptive value remain debated. Experimental Approach Using indirect calorimetry, telemetry, thermal gradient studies and pharmacological studies, we examined the thermal and metabolic responses of mice treated with a shock ...
Arely Tinajero   +7 more
wiley   +1 more source

Antagonistic AI [PDF]

open access: yesarXiv
The vast majority of discourse around AI development assumes that subservient, "moral" models aligned with "human values" are universally beneficial -- in short, that good AI is sycophantic AI. We explore the shadow of the sycophantic paradigm, a design space we term antagonistic AI: AI systems that are disagreeable, rude, interrupting, confrontational,
arxiv  

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