Results 171 to 180 of about 557,947 (269)

Behavioral Therapy as an Adjunct to Buprenorphine Treatment for Opioid Use Disorder: A Secondary Analysis of 4 Randomized Clinical Trials.

JAMA Netw Open
McHugh RK, Bailey AJ, McConaghy BA, Weiss RD, Fiellin DA, Hillhouse M, Moore BA, Fitzmaurice GM.   +7 more
europepmc   +1 more source

Duration of Methadone and Buprenorphine-Naloxone Treatment.

JAMA Netw Open
Kleinman RA, Kurdyak P.
europepmc   +1 more source

Implementation of Medication Disposal Programs and Availability of Same-Day Naloxone at Community Pharmacies: Protocol for a Secret Shopper Caller Approach.

JMIR Res Protoc
Egan KL, Lewis B, Fields K, McMillian Iii J, Graves RL, Kline DM, Eldridge LA.   +6 more
europepmc   +1 more source

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CLINICAL PHARMACOLOGY OF NARCOTIC ANTAGONISTS *

Annals of the New York Academy of Sciences, 1978
Both naloxone and naltrexone are effective narcotic antagonists with minimal agonistic effects and a wide margin of safety. Naloxone is useful in the treatment of narcotic overdose and it is helpful in the quantification of physical dependence. Naltrexone is pharmacologically successful as an orally effective, long-acting antagonist but its clinical ...
C. O'brien, R. Greenstein, J. Ternes, G. Woody   +3 more
semanticscholar   +4 more sources

Narcotic antagonists. 4. Carbon-6 derivatives of N-substituted noroxymorphones as narcotic antagonists.

Journal of Medicinal Chemistry, 1975
A series of new narcotic antagonists has been synthesized by modifying the C-6 carbonyl group in naloxone (Ia) and naltrexone (Ib). New functional units were introduced by reaction with various phosphorus and sulfur ylides and alkyllithium reagents.
E. Hahn, J. Fishman, R. Heilman
semanticscholar   +4 more sources

Discriminative properties of narcotic antagonists.

Psychopharmacology communications, 1976
There have been many recent reports characterizing the discriminative properties of morphine and related narcotic analgesics in a variety of experimental paradigms, predominantly in the rat (see preceding chapter). It is becoming increasingly evident that a strong association exists between the discriminative properties of these drugs in animals and ...
S. Holtzman, H. Shannon, G. J. Schaefer
semanticscholar   +4 more sources

Aftercare on narcotic antagonists: prospects and problems.

International Journal of the Addictions, 1976
This study examines the problems and prospects of aftercare of the multiple treatment failure opiate addict who is being treated with narcotic antagonists (primarily naltrexone). At the time of this paper, 21 patients had been admitted to the Drug Addiction Research Project at McLean Hospital, with a retention rate of 42%. "Completers," "noncompleters,"
M. Rawlins, M. Randall
semanticscholar   +4 more sources

Narcotic Antagonists as Analgesics

Science, 1962
2-Dimethylallyl-5,9-dimethyl-2′-hydroxybenzomorphan (Win 20,228) was found to be a weak antagonist of morphine and meperidine, whereas 2-allyl-5-ethyl-2′-hydroxy-9-methyl-6,7-benzomorphan (Win 19,362) and 2-allyl-2′-hydroxy-5,9-dimethyl-6,7-benzomorphan (Win 19,631) were about three times as potent as nalorphine.
Jane Telford, J. G. Bird, Anne K. Pierson, Louis S. Harris, Sydney Archer, Noel F. Albertson, Arthur S. Keats, C. N. Papadopoulos   +7 more
openaire   +3 more sources

Investigation into the use of narcotic antagonists in the treatment of a stereotypic behavior pattern (crib-biting) in the horse.

American Journal of Veterinary Research, 1987
Crib-biting in horses is a repetitive behavior pattern which may involve the activation of both narcotic receptors and dopamine receptors in the CNS. Crib-biting frequency, determined in 7 nontreated horses under controlled conditions, was usually linear
N. Dodman, Louis Shuster, Michael H. Court, Ross Dixon   +3 more
semanticscholar   +1 more source