Results 61 to 70 of about 554,314 (294)
Academic Emergency Medicine, Volume 32, Issue 4, Page 426-433, April 2025.Abstract Background Pain management is a critical part of treatment in patients with chest trauma. Opioids and nonsteroidal anti‐inflammatory drugs have been the most commonly used medications. However, their side effects have drawn attention to other medications.
Hossein Zabihi Mahmoodabadi +4 more
wiley +1 more source
Border fortification and legibility: Evidence from Afghanistan
American Journal of Political Science, EarlyView.Abstract States often fortify their borders against militant threats. How do these efforts shape civilian welfare and perceptions in borderland communities? I conceptualize border fortification as a legibility‐building endeavor. By bolstering state reach in areas of weak historical penetration, fortification enhances the government's capacity for ...
Christopher W. Blair
wiley +1 more source
Coordination on Time-Varying Antagonistic Networks [PDF]
arXiv, 2021 This paper studies coordination problem for time-varying networks suffering from antagonistic information, quantified by scaling parameters. By such a manner, interacting property of the participating individuals and antagonistic information can be quantified in a fully decoupled perspective, thus benefiting from merely directed spanning tree ...
arxiv
Application and Assessment of Deep Learning for the Generation of Potential NMDA Receptor Antagonists [PDF]
, 2020 Uncompetitive antagonists of the N-methyl D-aspartate receptor (NMDAR) have demonstrated therapeutic benefit in the treatment of neurological diseases such as Parkinson's and Alzheimer's, but some also cause dissociative effects that have led to the synthesis of illicit drugs.
arxiv +1 more source
Long-acting κ opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity [PDF]
, 2012 Background: Nor-BNI, GNTI and JDTic induce κ opioid antagonism that is delayed by hours and can persist for months. Other effects are transient. It has been proposed that these drugs may be slowly absorbed or distributed, and may dissolve in cell ...
Beguin, Cecile Andree +7 more
core +1 more source
Landowners Meet Drug Traffickers: Coercive Networks and Violence in Rural Colombia
Antipode, EarlyView.Abstract The transport of drugs and the flow of drug proceeds have a major impact on the social and economic configuration of the rural areas affected by them. Though this is widely acknowledged, the impact of illicit economies on agrarian social conflicts remains unclear. Using the case of the marijuana trade in the agrarian societies of the Magdalena
Luis David Castillo Rojas +1 more
wiley +1 more source
Inferring Synergistic and Antagonistic Interactions in Mixtures of Exposures [PDF]
arXiv, 2022 There is abundant interest in assessing the joint effects of multiple exposures on human health. This is often referred to as the mixtures problem in environmental epidemiology and toxicology. Classically, studies have examined the adverse health effects of different chemicals one at a time, but there is concern that certain chemicals may act together ...
arxiv
Method of Administering Narcotic Antagonists and Analgesics and Novel Dosage Forms Containing Same [PDF]
, 1984 The invention provides a novel method of administering narcotic antagonists, narcotic analgesics and related compounds, and novel dosage forms containing those compounds which are adapted for nasal administration. The nasal dosage forms disclosed include
Hussain, Anwar A.
core +1 more source
British Journal of Pharmacology, Volume 182, Issue 11, Page 2487-2502, June 2025.Background and Purpose Hyoscine butylbromide (HBB) has a low oral (PO) bioavailability. Further, limited data on its activity on non‐gastrointestinal (GI) smooth muscle spasms after oral dosing are available, causing its effects beyond the GI tract to be questioned.
Sara Traserra +4 more
wiley +1 more source