Results 31 to 40 of about 3,767,146 (252)

[Overdose deaths from narcotic drugs and psychotropic substances in Russia (an analysis of materials for the period 2003 to 2018)].

open access: yesSudebno-meditsinskaia ekspertiza, 2019
The purpose of the work is to study the prevalence of overdose deaths from narcotic drugs and psychotropic substances in Russia, as determined by forensic autopsies, for the period 2003 to 2018.
V. Vladimirov   +3 more
semanticscholar   +1 more source

The Evolution of Substance Use Coverage in the Philadelphia Inquirer [PDF]

open access: yesarXiv, 2023
The media's representation of illicit substance use can lead to harmful stereotypes and stigmatization for individuals struggling with addiction, ultimately influencing public perception, policy, and public health outcomes. To explore how the discourse and coverage of illicit drug use changed over time, this study analyzes 157,476 articles published in
arxiv  

Dissecting the novel abilities of aripiprazole: The generation of anti-colorectal cancer effects by targeting Gαq via HTR2B

open access: yesActa Pharmaceutica Sinica B, 2023
Colorectal cancer (CRC) is a type of malignant tumor that seriously threatens human health and life, and its treatment has always been a difficulty and hotspot in research.
Haowei Liu   +5 more
doaj  

The activation of GABAergic neurons in the hypothalamic tuberomammillary nucleus attenuates sevoflurane and propofol-induced anesthesia in mice

open access: yesFrontiers in Pharmacology, 2023
Background: The histaminergic neurons in the hypothalamic tuberomammillary nucleus (TMN) have been suggested to play a vital role in maintaining a rising state.
Jing Liu   +31 more
doaj   +1 more source

Two parallel medial prefrontal cortex-amygdala pathways mediate memory deficits via glutamatergic projection in surgery mice

open access: yesCell Reports, 2023
Summary: The neural circuit mechanisms underlying postoperative cognitive dysfunction (POCD) remain elusive. We hypothesized that projections from the medial prefrontal cortex (mPFC) to the amygdala are involved in POCD.
Xiao-Yu Sun   +7 more
doaj  

Towards Toxic and Narcotic Medication Detection with Rotated Object Detector [PDF]

open access: yesarXiv, 2021
Recent years have witnessed the advancement of deep learning vision technologies and applications in the medical industry. Intelligent devices for special medication management are in great need of, which requires more precise detection algorithms to identify the specifications and locations.
arxiv  

Adjudication and Treatment of Narcotic Drug Offenders in Ghana

open access: yesThe Journal of Medicine, Law & Public Health, 2023
Narcotic drug trafficking is a criminal and punishable offence in every country the world over. The use of certain narcotic drugs, on the other hand (especially marijuana), has been legalised in some countries, but under strict regulations.
Jacob Agboli
doaj   +1 more source

Hyperbolic Molecular Representation Learning for Drug Repositioning [PDF]

open access: yesarXiv, 2022
Learning accurate drug representations is essential for task such as computational drug repositioning. A drug hierarchy is a valuable source that encodes knowledge of relations among drugs in a tree-like structure where drugs that act on the same organs, treat the same disease, or bind to the same biological target are grouped together.
arxiv  

Drug Selection via Joint Push and Learning to Rank [PDF]

open access: yesIEEE/ACM Transactions on Computational Biology and Bioinformatics ( Volume: 17, Issue: 1, 01 Jan.-Feb. 2020), 2018
Selecting the right drugs for the right patients is a primary goal of precision medicine. In this manuscript, we consider the problem of cancer drug selection in a learning-to-rank framework. We have formulated the cancer drug selection problem as to accurately predicting 1). the ranking positions of sensitive drugs and 2).
arxiv   +1 more source

AMFPMC -- An improved method of detecting multiple types of drug-drug interactions using only known drug-drug interactions [PDF]

open access: yesarXiv, 2023
Adverse drug interactions are largely preventable causes of medical accidents, which frequently result in physician and emergency room encounters. The detection of drug interactions in a lab, prior to a drug's use in medical practice, is essential, however it is costly and time-consuming.
arxiv  

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