Results 31 to 40 of about 74,644 (322)

Microglia-derived TNF-α inhibiting GABAergic neurons in the anterior lateral bed nucleus of the stria terminalis precipitates visceral hypersensitivity induced by colorectal distension in rats

Neurobiology of Stress, 2022
Irritable bowel syndrome (IBS) is a common and debilitating gastrointestinal disorder that is exacerbated by stress and characterized by abdominal pain.
Ning-Ning Ji, Qing-Xiang Meng, Ying Wang, Zi-Ming Zhou, Yu Song, Rong Hua, Yong-Mei Zhang   +6 more
doaj   +1 more source

Protocol to study projection-specific circuits in the basal ganglia of adult mice using viral vector tracing, optogenetics, and patch-clamp technique

STAR Protocols, 2023
Summary: Analysis of synaptic strength and plasticity provides functional insights of complicated neural circuits. Here, we describe steps for cell- and projection-specific optogenetic manipulation of divergent basal ganglia circuits using anterograde ...
Ya-Wei Ji, Xiang-Ying Xu, Cui Yin, Chunyi Zhou, Cheng Xiao   +4 more
doaj   +1 more source

Aberrant expression of FBXO22 is associated with propofol-induced synaptic plasticity and cognitive dysfunction in adult mice

Frontiers in Aging Neuroscience, 2022
Recent observation demonstrated that prolonged anesthesia modifies brain synaptic architecture in all ages, including adult. Propofol is the most commonly utilized anesthetics at clinic.
Xiaoxuan Yang, Chen Chen, Chen Chen, Dongmei Qu, Yanping Liu, Yanping Liu, Ning Wang, Ning Wang, Haibi Wang, Haibi Wang, Youjia Fan, Yushan Zhou, Buwei Yu, Qingsheng Xue, Yuqing Wu, Yuqing Wu, Han Lu   +16 more
doaj   +1 more source

Adjudication and Treatment of Narcotic Drug Offenders in Ghana

The Journal of Medicine, Law & Public Health, 2023
Narcotic drug trafficking is a criminal and punishable offence in every country the world over. The use of certain narcotic drugs, on the other hand (especially marijuana), has been legalised in some countries, but under strict regulations.
Jacob Agboli
doaj   +1 more source

The activation of GABAergic neurons in the hypothalamic tuberomammillary nucleus attenuates sevoflurane and propofol-induced anesthesia in mice

Frontiers in Pharmacology, 2023
Background: The histaminergic neurons in the hypothalamic tuberomammillary nucleus (TMN) have been suggested to play a vital role in maintaining a rising state.
Jing Liu, Jing Liu, Jing Liu, Jing Liu, Xiao Liu, Xiao Liu, Xiao Liu, Wen-Yu Zhou, Wen-Yu Zhou, Wen-Yu Zhou, Jun Gan, Jun Gan, Jun Gan, Jie Wang, Jie Wang, Jie Wang, Qi Zhang, Qi Zhang, Qi Zhang, Jun-Liang Li, Jun-Liang Li, Jun-Liang Li, Zhong-Shan Shen, Zhong-Shan Shen, Zhong-Shan Shen, Yue-Ying Zhang, Qiong-Yao Tang, Qiong-Yao Tang, Qiong-Yao Tang, Zhe Zhang, Zhe Zhang, Zhe Zhang   +31 more
doaj   +1 more source

Hypothesis of Rfmra Development – the Receptor-focused Magnetic and Resonant Anesthesia [PDF]

, 2016
This article is described the hypothesis of the solution how to create the "ideal anesthesia". Theoretical justification of the innovative technique of the Receptor-focused Magnetic Resonance anesthesia is offered. It should be use the "ideal anesthetic"
Golyanishchev, M. (Maxim)
core   +2 more sources

Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson’s disease model mice

Cell Death and Disease
Neuroinflammation is a key factor in the pathogenesis of Parkinson’s disease (PD). Activated microglia in the central nervous system (CNS) and infiltration of peripheral immune cells contribute to dopaminergic neuron loss. However, the role of peripheral
Wei Song, Zi-ming Zhou, Le-le Zhang, Hai-feng Shu, Jin-ru Xia, Xia Qin, Rong Hua, Yong-mei Zhang   +7 more
doaj   +1 more source

Physician Referral Patterns to Physical Therapists for Managing Knee Osteoarthritis: A Retrospective Analysis of Electronic Health Records from an Integrated Health System

Arthritis Care &Research, Accepted Article.
Objectives This study aims to describe the frequency and timing of physician referrals to physical therapists (PT) and other treatments prescribed over 12 months in patients with recent onset of knee osteoarthritis (KOA). The study also aims to identify determinants of early PT referrals.
Samannaaz S. Khoja, Joel M. Stevans, Gustavo J. Almeida, Clair Smith, Janet K. Freburger   +4 more
wiley   +1 more source

Impaired synaptic plasticity and decreased glutamatergic neuron excitability induced by SIRT1/BDNF downregulation in the hippocampal CA1 region are involved in postoperative cognitive dysfunction

Cellular & Molecular Biology Letters
Background Postoperative cognitive dysfunction (POCD) is a common complication after anesthesia/surgery, especially among elderly patients, and poses a significant threat to their postoperative quality of life and overall well-being.
Wei-Feng Wu, Chen Chen, Jia-Tao Lin, Xin-Hao Jiao, Wei Dong, Jie Wan, Qiang Liu, Yong-Kang Qiu, Ao Sun, Yi-Qi Liu, Chun-Hui Jin, He Huang, Hui Zheng, Cheng-Hua Zhou, Yu-Qing Wu   +14 more
doaj   +1 more source

The Narcotic Drug Problem

The American Journal of the Medical Sciences, 1920
Mode of access: Internet.
openaire   +2 more sources