Strategies to deliver peptide drugs to the brain [PDF]
Lalatsa, Katerina +2 more
core +1 more source
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is managed after sinus surgery with topical corticosteroids. Given limited distribution of nasal steroid sprays, patients have the option of either steroid nasal irrigation (SNI) or exhalation delivery system with fluticasone (EDS‐FLU).
Daniel Xiao +3 more
wiley +1 more source
Alzheimer's disease: A case study involving EEG-based fE/I ratio and pTau-181 protein analysis through nasal administration of <i>Saraswata Ghrita</i>. [PDF]
Badal R +6 more
europepmc +1 more source
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel +13 more
wiley +1 more source
Uncovering Cystic Fibrosis Carrier: Insights From a Heterozygous CFTR‐F508del Rabbit Model
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disorder frequently associated with impaired mucociliary clearance and bacterial infection. Individuals carrying a single cystic fibrosis transmembrane conductance regulator (CFTR) mutation exhibit partial CFTR dysfunction and are increasingly recognized as being at risk ...
Do‐Yeon Cho +9 more
wiley +1 more source
Mechanically Activated Luminescence in Polyurethanes Incorporating Calixarene Mechanophores
The conformational flexibility of a calix[4]arene is exploited to obtain a reversible mechanoluminophore featuring a pyrene excimer couple at the upper rim. Stretching a linear polyurethane incorporating such mechanophore results in luminescence color change from yellow–green to blue, consistent with a force‐induced conformational motion of the ...
Lucia Visieri +3 more
wiley +2 more sources
Dexmedetomidine nasal administration improves perioperative sleep quality and neurocognitive deficits in elderly patients undergoing general anesthesia. [PDF]
He J +5 more
europepmc +1 more source
ABSTRACT Background Olfactory dysfunction is common in aging and an early symptom of neurodegenerative diseases, but how structural (olfactory bulb [OB] volume) and functional (olfactory network [OFN] functional connectivity [FC]) brain features interact to shape odor identification ability remains unclear.
Weiyi Zeng +4 more
wiley +1 more source
Preventive nasal administration of flagellin restores antimicrobial effect of gentamicin and protects against a multidrug-resistant strain of <i>Pseudomonas aeruginosa</i>. [PDF]
Maia AR +7 more
europepmc +1 more source
A CGRP receptor antagonist peptide formulated for nasal administration to treat migraine. [PDF]
von Mentzer B +10 more
europepmc +1 more source

