Nasal Residence Depending on the Administered Dosage Form: Impact of Formulation Type on the In Vivo Nasal Retention Time of Drugs in Rats [PDF]
PharmaceuticsBackground/Objectives: The precise control of drug absorption through the nasal mucosa following intranasal administration can be achieved through optimal formulation development that considers the nasal retention properties of the administered dosage ...
Daisuke Inoue, Yoshihiro Seto, Hideto To
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Study of surfactants influence on the noopept releasing from the nasal dosage form
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020 The nasal route of drug administration, as is well known, is characterized by some advantages: absorption rate and rapid onset of therapeutic effect, availability of drug delivery without hepatic first-pass elimination, it is suitable and easily ...
B. S. Burlaka +2 more
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STUDY OF REOLOGICAL PROPERTIES OF CAPTOPRIL NASAL DOSAGE FORM
Zaporožskij Medicinskij Žurnal, 2013 The aim of this work was to study properties of ACE inhibitor captopril semisolid dosage form which was developed on the department of technology of medication in Zaporozhye State Medical University. The complex of physico-chemical, pharmacotechnological
Аlmochаmаd Guмаа Аbdullах +3 more
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Study of excipients influence on the noopept releasing from the nasal dosage form
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019 The development of medicines for fast delivery is the actual direction of modern pharmacy. In this connection, the nasal route of drug administration is perspective and has some advantages. The greater permeability of nasal mucosa with large surface area
B. S. Burlaka +2 more
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The study of consistent properties of the vasopressin nasal dosage form
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016 Evaluation of consistent properties is an important and integral part of investigations on the creation of semisolid nasal pharmacotherapeutic agents. The aim of this work is the study of consistent properties of developed nasal semisolid dosage form ...
Al Nukarii Abdulkarim +2 more
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Efficacy and limitations of systemic corticosteroids in patients with CRSwNP compared to alternative therapies with monoclonal antibodies: real-life of 101 patients from the Lazio region, Italy [PDF]
Frontiers in AllergyChronic Rhinosinusitis with Nasal Polyps (CRSwNP) is a chronic inflammatory disease. Its severe uncontrolled form may share, with asthma and atopic dermatitis, the pathophysiological mechanism of T helper 2 inflammation, characterized by tissue ...
F. Anastasi +8 more
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Thermogravimetric studies of a nasal preparation with an interleukin-1β (IL-1Ra) antagonist
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021 Interleukin-1 receptor antagonist (IL-1Ra) is an active pharmaceutical ingredient obtained by the method of gene transformation of Escherichia coli, provides a neuroprotective effect, namely – inhibition of oxidative modification of proteins ...
B. S. Burlaka
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Optimization of the composition of a nasal medicine with interleukin-1 antagonist β
Фармацевтичний журнал, 2021 In the development of new effective and safe drugs an important place is occupied by the issue of ensuring the stability of the dosage form. In this case, a significant contribution to this problem is made directly by the nature of the active ...
B. S. Burlaka
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021 Uncomplicated hypertensive crises without acute or progressive damage to the target organs pose a potential threat to the patient’s life and require rapid reduction of arterial pressure within hours or days in an outpatient setting. The existing protocol
I. L. Kechyn +2 more
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Human Lactobacillus Biosurfactants as Natural Excipients for Nasal Drug Delivery of Hydrocortisone
Pharmaceutics, 2022 The inclusion of a chemical permeation enhancer in a dosage form is considered an effective approach to improve absorption across the nasal mucosa. Herein we evaluated the possibility of exploiting biosurfactants (BS) produced by Lactobacillus gasseri ...
Elisa Corazza +7 more
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