Results 211 to 220 of about 49,420 (307)

Comparison of Auto‐Contouring Tools for Delineation of Normal Organs at Risk in Paediatric Patients Undergoing Radiotherapy

open access: yesJournal of Medical Radiation Sciences, EarlyView.
Contouring organs at risk (OARs) manually in paediatric patients undergoing cranial‐spinal radiation therapy (CSI) is a time‐consuming, labour‐intensive task. This study aims to assess the accuracy and clinical acceptability of auto‐contours produced by the Siemens DirectORGANS auto‐contouring software on paediatric patients receiving CSI treatment ...
Isabel Cant   +6 more
wiley   +1 more source

Severe allergic reaction to ustekinumab reinitiation in a pediatric patient with Crohn's disease: A case report

open access: yesJPGN Reports, EarlyView.
Abstract Ustekinumab (UST) is a monoclonal antibody used in the management of moderate to severe inflammatory bowel disease. While generally well‐tolerated, serious adverse reactions, including hypersensitivity and anaphylaxis, have been documented, specifical following the initial intravenous (IV) dose.
Kennedy Sparling   +2 more
wiley   +1 more source

Dupilumab as an effective therapy for eosinophilic esophagitis in pediatric patients weighing less than 15 kilograms

open access: yesJPGN Reports, EarlyView.
Abstract Objectives Eosinophilic esophagitis (EoE) is a type 2 cytokine‐mediated chronic inflammatory condition leading to esophageal dysfunction. Dupilumab blocks IL‐4 and IL‐13 signaling, which are key inflammatory mediators in EoE and other allergic disorders.
Sindhura Kasturi   +6 more
wiley   +1 more source

Successful treatment of eosinophilic esophagitis with upadacitinib prescribed for atopic dermatitis

open access: yesJPGN Reports, EarlyView.
Abstract We describe a pediatric patient treated with upadacitinib for atopic dermatitis (AD) who subsequently achieved sustained clinical and histologic remission of eosinophilic esophagitis (EoE). Upadacitinib is an oral small molecule selective Janus kinase 1 inhibitor that inhibits janus kinase‐signal transduction and activation of transcription ...
Nathalie Nguyen, Maureen Bauer
wiley   +1 more source

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