Results 51 to 60 of about 149,571 (273)

Human Lactobacillus Biosurfactants as Natural Excipients for Nasal Drug Delivery of Hydrocortisone

open access: yesPharmaceutics, 2022
The inclusion of a chemical permeation enhancer in a dosage form is considered an effective approach to improve absorption across the nasal mucosa. Herein we evaluated the possibility of exploiting biosurfactants (BS) produced by Lactobacillus gasseri ...
Elisa Corazza   +7 more
doaj   +1 more source

Development of a nasal spray containing aminocaproic acid and a copolymer of N-vinylpyrrolidone and 2-methyl-5-vinylpyridine for use in the prevention of influenza and other viral respiratory infections

open access: yesТонкие химические технологии, 2020
Objectives. Prevention of influenza and viral respiratory infections is one of the major public health problems today. The aim of the study was to develop the formulation and production conditions for a nasal spray that can be used in the prevention of ...
A. S. Karpova
doaj   +1 more source

Selection of excipients for the purpose of creating an intranasal gel of interleukin-1 receptor antagonist β (IL-1ra)

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
There is a negative dynamic of the spread of cerebrovascular diseases, which often lead to disability or death in patients in the world, today. Such diseases are characterized by acute disorders of cerebral metabolism and blood circulation, against the ...
B. S. Burlaka   +4 more
doaj   +1 more source

Development of mucoadhesive sprayable gellan gum fluid gels [PDF]

open access: yes, 2015
The nasal mucosa provides a potentially good route for local and systemic drug delivery. However, the protective feature of the nasal cavity make intranasal delivery challenging.
Mahdi, Mohammed H.   +2 more
core   +1 more source

Nose to brain delivery of nanosuspensions with first line antiviral agents is alternative treatment option to Neuro-AIDS treatment

open access: yesHeliyon, 2022
Intranasal drug delivery is one of the uprising areas of the research in targeting drug to the brain. Nose to brain drug delivery follows the olfactory pathway and purportedly known to be more efficient to deliver neuro-therapeutics to the brain by ...
Smita P. Kakad   +3 more
doaj   +1 more source

Gastroretentive microparticles for drug delivery applications [PDF]

open access: yes, 2011
Many strategies have been proposed to explore the possibility of exploiting gastroretention for drug delivery. Such systems would be useful for local delivery, for drugs that are poorly soluble at higher pH or primarily absorbed from the proximal small ...
Conway, Barbara R   +5 more
core   +1 more source

Ex-Vivo and In-Vivo Assessment of Cyclamen europaeum Extract After Nasal Administration

open access: yesPharmaceutics, 2019
Rhinosinusitis is a prevalent disorder with a severe impact on the health-related quality of life. Saponins of Cyclamen europaeum exert a clinically proven curative effect on rhinosinusitis symptoms when instilled into the nasal cavity, however, more ...
Francisco Fernández-Campos   +5 more
doaj   +1 more source

Comparative study of the specific activity of soft application drugs with vinpocetine

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2022
In modern neurology, the main component of successful treatment of cerebrovascular pathology is pharmacotherapy. At the same time, the arsenal of effective medicines of evidence-based medicine in this area is quite limited.
V. V. Hladyshev   +6 more
doaj   +1 more source

Study of basis-transmitter influence on biopharmaceutical properties of diltiazem nasal dosage form

open access: yesZaporožskij Medicinskij Žurnal, 2013
It is set that the type of basis-transmitter has an influence on release of diltiazem from intranasal ointments. Variance analysis of researches results showed that transmitter on the basis of methylcellulose glycerogel provides optimal diltiazem ...
V. V. Gladyshev   +2 more
doaj   +1 more source

Development and validation of a simple method for the determination of triamcinolone acetonide in nasal spray

open access: yesSaudi Pharmaceutical Journal, 2023
A rapid, convenient, and sensitive analytical technique for quantitative analysis of triamcinolone acetonide (TAC) in pharmaceutical nasal spray dosage form using the blue tetrazolium colorimetric reaction and UV spectrophotometric method was developed ...
Haya S. Alzeer   +3 more
doaj   +1 more source

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