Results 61 to 70 of about 149,571 (273)

Features of the use of topical preparations of framycetin sulfate in the treatment of rhinosinusitis

Медицинский совет, 2021
Introduction. Acute rhinosinusitis is one of the most common infectious diseases in the world. But despite their predominantly viral nature, the activation of their own microflora occurring during the disease, the addition of pathogenic and the ...
S. A. Eremin, I. M. Dyakov, S. S. Pavlova   +2 more
doaj   +1 more source

Formulation and kinetic modeling of curcumin loaded intranasal mucoadhesive microemulsion

Journal of Pharmacy and Bioallied Sciences, 2012
It is a challenge to develop the optimum dosage form of poorly water-soluble drugs and to target them due to limited bioavailability, intra and inter subject variability.
B Mikesh Patel, Surjyanarayan Mandal, K S Rajesh   +2 more
doaj   +1 more source

Assay of Desmopressin Acetate in Nasal Spray: Development of Validated Pre Column HPLC-Fluorescence Method [PDF]

Advanced Pharmaceutical Bulletin, 2017
Purpose: Desmopressin acetate (DDAPV), a synthetic analogue of vasopressin, has been recommended to be used in diabetes insipidus, mild forms of hemophilia and Von Willebrand disease.
Neeraj Upmanyu, Pawan Kumar Porwal
doaj   +1 more source

Nano-adjuvanted dry powder vaccine for the mucosal immunization against airways pathogens

Frontiers in Veterinary Science, 2023
Nasal vaccination has been shown to provide optimal protection against respiratory pathogens. However, mucosal vaccination requires the implementation of specific immunization strategies to improve its effectiveness. Nanotechnology appears a key approach
Elena Canelli, Luca Ferrari, Paolo Borghetti, Francesco Candela, Nkemjika Sopuru Abiakam, Annalisa Bianchera, Annalisa Bianchera, Francesca Buttini, Francesca Buttini, Gian Enrico Magi, Fabio Sonvico, Fabio Sonvico, Paolo Martelli, Ruggero Bettini, Ruggero Bettini   +14 more
doaj   +1 more source

Consideration of nasal dosage form

, 2021
The nasal drug delivery system are incredibly versatile and although the number of potential pharmacons to be employed are quite limited . Nasal drug delivery are incredibly easy to use and also do not intimidate the patient which has a beneficial effect
Ghaedi, Zahra
core  

Efficacy and safety of two Ayurvedic dosage forms for allergic rhinitis: Study protocol for an open-label randomized controlled trial

Trials, 2020
Background Allergic rhinitis (AR) is an immune response of the nasal mucosa to airborne allergens and involves nasal congestion, watery nasal discharge, itching of the nose, and sneezing.
Jeevani Maheshika Dahanayake, Pathirage Kamal Perera, Priyadarshani Galappaththy, Dulani Samaranayake   +3 more
doaj   +1 more source

Intranasal delivery of Clozapine using nanoemulsion-based in-situ gels: An approach for bioavailability enhancement

Saudi Pharmaceutical Journal, 2021
Limited solubility and hepatic first-pass metabolism are the main causes of low bioavailability of anti-schizophrenic drug, Clozapine (CZP). The objective of the study was to develop and validate nanoemulsion (NE) based in-situ gel of CZP for intranasal ...
Nourhan A. Abdulla, Gehan F. Balata, Hanaa A. El-ghamry, Eman Gomaa   +3 more
doaj   +1 more source

Solid Lipid Nanoparticles Containing Dopamine and Grape Seed Extract: Freeze-Drying with Cryoprotection as a Formulation Strategy to Achieve Nasal Powders

Molecules, 2023
(1) Background: DA-Gelucire® 50/13-based solid lipid nanoparticles (SLNs) administering the neurotransmitter dopamine (DA) and the antioxidant grape-seed-derived proanthocyanidins (grape seed extract, GSE) have been prepared by us in view of a possible ...
Elvira De Giglio, Udo Bakowsky, Konrad Engelhardt, Antonello Caponio, Matteo La Pietra, Stefania Cometa, Stefano Castellani, Lorenzo Guerra, Giuseppe Fracchiolla, Maria Luana Poeta, Rosanna Mallamaci, Rosa Angela Cardone, Stefano Bellucci, Adriana Trapani   +13 more
doaj   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Mucoadhesive drug delivery systems

Journal of Pharmacy and Bioallied Sciences, 2011
Mucoadhesion is commonly defined as the adhesion between two materials, at least one of which is a mucosal surface. Over the past few decades, mucosal drug delivery has received a great deal of attention.
Rahamatullah Shaikh, Thakur Raghu Raj Singh, Martin James Garland, A David Woolfson, Ryan F Donnelly   +4 more
doaj   +1 more source