Results 61 to 70 of about 7,945 (175)

Phase IIB, Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial of Intravenous Defibrotide for the Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome in COVID‐19

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio, Antonio José Martinez‐Mellado, Jonathan Kiwitt‐Cárdenas, José G. Clavel, Bartolomé García‐Perez, Pedro Castro, Maribel Diaz‐Ricart, Andrés Carrillo‐Alcaraz, Amparo López‐Bernús, Enrique Bernal Morell, Aychel Roura, Sonia Marín, Francisco‐José Ruiz‐López, Elena Solana‐Martinez, Domingo Martinez‐Baño, Carlos L. Albacete Moreno, Enriqueta Andreu Soler, Adrián Tellez Santoyo, Sara Fernández Méndez, Jose A. Noguera Velasco, Iria Cebreiros Lopez, Andrés Parrilla, Alberto Espuny‐Miró, David García‐Bernal, Miguel Blanquer, Andrés Sánchez‐Salinas, Francisca Iniesta, Cristina Hernandez Garcia, Manuel Muro, Alfredo Minguela Puras, Antonio Moreno‐Docón, Alberto M. Torres‐Cantero, Maria Munoz Garcia, Manuel Serrano, Massimo Iacobelli, Carmelo Carlo‐Stella, Lee‐Jen Wei, Paul G. Richardson, José M. Moraleda   +38 more
wiley   +1 more source

Implementation of less invasive surfactant administration in clinical practice-Experience of a mid-sized country.

PLoS ONE, 2020
OBJECTIVE:There are differences in the adoption rates of less invasive surfactant administration (LISA) worldwide. We aimed to describe and analyze the process of LISA introduction at the country level. METHODS:A standardized training program (33 courses
Tomasz Szczapa, Roman Hożejowski, Paweł Krajewski, Study Group   +3 more
doaj   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet, Marie Netchitaïlo, Fanny Fabre, Elise Belaidi, Claire Arnaud, Anne‐Laure Borel, Patrick Levy, Jean‐Louis Pépin, Renaud Tamisier   +8 more
wiley   +1 more source

Perioperative Management for Patients With Spinal Muscular Atrophy Undergoing Scoliosis Surgery: A Single‐Center Retrospective Study

Orthopaedic Surgery, EarlyView.
This largest Asian case series confirms that posterior spinal fusion for SMA scoliosis is safe and effective despite severe deformity and markedly impaired pulmonary function. Meticulous multidisciplinary care, including advanced airway planning, hemodynamic support, blood management, and proactive electrolyte correction, is critical to optimizing ...
Ai Hu, Xiuhua Zhang, Lulu Ma, Haisong Lu, Yulei Dong, Weiyun Chen, Yuguang Huang, Jianxiong Shen   +7 more
wiley   +1 more source

Medical Management With Mechanical Ventilation of a Dog With Severe Barium Sulfate Aspiration

Journal of Veterinary Emergency and Critical Care, EarlyView.
Abstract Objective To describe the medical management with mechanical ventilation of a dog with severe barium sulfate aspiration and concurrent canine acute eosinophilic dermatitis with edema. Case summary A 26‐month‐old castrated male Golden Retriever was presented in respiratory distress after the accidental administration of approximately 300 mL of ...
Mathieu V. Paulin, Allison A. Foster, Jennifer M. Loewen   +2 more
wiley   +1 more source

Effects of the angle of head‐down tilt on dynamic cerebral autoregulation during combined exposure to cephalad fluid shift and mild hypercapnia

Experimental Physiology, EarlyView.
Abstract Astronauts experience combined exposure to a cephalad fluid shift and mild hypercapnia during space missions, potentially contributing to health problems. Such combined exposure may weaken dynamic cerebral autoregulation. The magnitude of cephalad fluid shift varies between individuals, and dynamic cerebral autoregulation may be affected more ...
Tomokazu Kato, Yojiro Ogawa, Ken‐ichi Iwasaki   +2 more
wiley   +1 more source

Breathing irregularities and postnatal hypoxaemia in an experimental model of essential hypertension

The Journal of Physiology, EarlyView.
Abstract figure legend Neonatal spontaneously hypertensive rats (SHRs) exhibit inherent respiratory dysfunction in early life, including oscillatory breathing patterns and apnoeic events that cause oxygen desaturation and brain hypoxia, in addition to an impaired hypoxic ventilatory response.
Beatriz N. Vieira, Letícia R. Mendes, Sarah G. Mariano, Isabela P. Leirão, Emilson D. Pereira‐Junior, Milede H. Saraiva Paes, Pedro L. Katayama, Daniel B. Zoccal   +7 more
wiley   +1 more source

Nasal intermittent positive pressure ventilation in neonates with meconium aspiration syndrome

Pediatric Review: International Journal of Pediatric Research, 2020
Background: Nasal intermittent positive pressure ventilation ( NIPPV) as primary respiratorysupport in neonates with meconium aspiration syndrome (MAS) has not been studied. The presentstudy applied the use of NIPPV as a treatment modality in MAS and tried to identify factorspredicting NIPPV failure.
Dr. Jagadish. A.S., Dr. Vikranth Vikranth, Dr. Ravichander B.   +2 more
openaire   +2 more sources

Smart Face Masks as Wearable Respiratory Sensors: A Review of Sensor Technologies, Materials, and Future Directions

Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
This review highlights recent advances in smart face masks that actively monitor breathing. By integrating humidity, gas, temperature, pressure, strain, and triboelectric sensors, these masks track key respiratory parameters in real time. The article summarizes sensor mechanisms, compares performance across studies, and discusses challenges and future ...
Negin Faramarzi, Naseeh Backer Kannanthodi, Alice Nicole Casling, Babar Ali, Samira Lakouraj Mansouri, Alessandro Giuseppe D'aloia, Hossein Cheraghi Bidsorkhi, Maria Sabrina Sarto   +7 more
wiley   +1 more source

Flow-Synchronized Nasal Intermittent Positive Pressure Ventilation for Infants <32 Weeks' Gestation with Respiratory Distress Syndrome

Critical Care Research and Practice, 2012
Aim. To evaluate whether synchronized-NIPPV (SNIPPV) used after the INSURE procedure can reduce mechanical ventilation (MV) need in preterm infants with RDS more effectively than NCPAP and to compare the clinical course and the incidence of short-term ...
C. Gizzi, P. Papoff, I. Giordano, L. Massenzi, C. S. Barbàra, M. Campelli, V. Panetta, R. Agostino, C. Moretti   +8 more
doaj   +1 more source