Results 11 to 20 of about 602,823 (332)

Immune cell residency in the nasal mucosa may partially explain respiratory disease severity across the age range

Scientific Reports, 2021
Previous studies focusing on the age disparity in COVID-19 severity have suggested that younger individuals mount a more robust innate immune response in the nasal mucosa after infection with SARS-CoV-2.
Konner Winkley, Dithi Banerjee, Todd Bradley, Boryana Koseva, Warren A. Cheung, Rangaraj Selvarangan, Tomi Pastinen, Elin Grundberg   +7 more
doaj   +2 more sources

Symbiotic microbiome Staphylococcus aureus from human nasal mucus modulates IL-33-mediated type 2 immune responses in allergic nasal mucosa

BMC Microbiology, 2020
Background The host-microbial commensalism can shape the innate immune responses in respiratory mucosa and nasal microbiome also modulates front-line immune mechanism in the nasal mucosa.
Yung Jin Jeon, Chan Hee Gil, Jina Won, Ara Jo, Hyun Jik Kim   +4 more
doaj   +2 more sources

Epithelial Barrier in the Nasal Mucosa, Related Risk Factors and Diseases.

Int Arch Allergy Immunol, 2023
As the first line of defense against risk factors, the nasal epithelial barrier maintains homeostasis in nasal mucosa. The composition of the epithelial barrier contains physical, chemical, immune, and microbiological barriers.
Zhang R, Zhang L, Li P, Pang K, Liu H, Tian L.   +5 more
europepmc   +2 more sources

Impairment mechanism of nasal mucosa after radiotherapy for nasopharyngeal carcinoma [PDF]

Frontiers in Oncology, 2022
The nasal mucosa, which performs the crucial functions of filtering, humidifying and temperature regulation, is one of the most vulnerable areas of nasopharyngeal carcinoma (NPC) patients after radiotherapy (RT).
Caishan Fang, Yu Zhong, Tengyu Chen, Dan Li, Chunqiao Li, Xiangjun Qi, Junxia Zhu, Ruizhi Wang, Jinxiang Zhu, Shunlan Wang, Yan Ruan, Min Zhou   +11 more
doaj   +2 more sources

Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue. [PDF]

PLoS ONE, 2012
BACKGROUND: Staphylococcus aureus (S. aureus) plays an important role in the pathogenesis of severe chronic airway disease, such as nasal polyps. However the mechanisms underlying the initiation of damage and/or invasion of the nasal mucosa by S.
XiangDong Wang, Nan Zhang, Sarah Glorieux, Gabriele Holtappels, Mario Vaneechoutte, Olga Krysko, Luo Zhang, Demin Han, Hans J Nauwynck, Claus Bachert   +9 more
doaj   +2 more sources

Protocol for optimized nasal mucosa sample processing to obtain high-quality scRNA-seq and scATAC-seq data [PDF]

STAR Protocols
Summary: Examining nasal mucosa samples is crucial for nasal cavity disease research and diagnosis. Simultaneously obtaining high-quality data for single-cell transcriptomics (single-cell RNA sequencing [scRNA-seq]) and epigenomics (single-cell assay for
Yaling Huang, Yisha Wu, Shikai Han, Qiaoling Wang, Guomingxiu Cong, Zhongzhen Liu, Shuyan Guan, Xiaojuan Huang, Ying Liu, Jianhua Yin, Jinmei Xue, Chuanyu Liu   +11 more
doaj   +2 more sources

Rat nasal mucosa‐derived ectodermal mesenchymal stem cells: A new therapeutic option for chronic rhinosinusitis [PDF]

Immunity, Inflammation and Disease
Objective To investigate the effect of nasal mucosa‐derived ectodermal mesenchymal stem cells (NM‐EMSCs) on the inflammatory state of rats with chronic rhinosinusitis (CRS) and the underlying therapeutic mechanism.
Liujin Li, ZhaoHui Liu, ChunLin Zhang, YiLin Long, TianWen Yang   +4 more
doaj   +2 more sources

Microcirculation in the nasal mucosa.

Folia Pharmacologica Japonica, 1999
The nasal mucosa has important physiological roles, including the removal of foreign bodies and the warming and humidification of inspired air. The microcirculation in the nasal mucosa facilitates the above processes and plays a role in the periodic swelling and shrinking of the nasal mucosa.
Hiromichi Tsuru, Hiroshi Watanabe
openaire   +5 more sources

Upregulation of the Vitamin D Receptor in the Nasal Mucosa of Patients With Allergic Rhinitis [PDF]

Journal of Rhinology, 2021
Background and Objectives Vitamin D modulates immunity, including that of allergic diseases, and plays its roles through contact with vitamin D receptors (VDR).
Hyeon Geun Kim, Da Bin Lee, Tae Hoon Lee, Bo Yoon Choi, Mun Soo Han, Sang Hag Lee, Tae Hoon Kim   +6 more
doaj   +1 more source

Expansion of cytotoxic tissue-resident CD8+ T cells and CCR6+CD161+ CD4+ T cells in the nasal mucosa following mRNA COVID-19 vaccination

Nature Communications, 2022
Vaccines against SARS-CoV-2 have shown high efficacy in clinical trials, yet a full immunologic characterization of these vaccines, particularly within the human upper respiratory tract, is less well known.
A. Ssemaganda, Huong Mai Nguyen, Faisal Nuhu, Naima Jahan, C. Card, S. Kiazyk, G. Severini, Y. Keynan, R. Su, H. Ji, B. Abrenica, P. McLaren, T. Ball, J. Bullard, P. V. Van Caeseele, D. Stein, L. Mckinnon   +16 more
semanticscholar   +1 more source