Results 21 to 30 of about 598,565 (184)

Development of a nasal mucosa-removal model for evaluating cell therapy

Regenerative Therapy, 2021
Introduction: Endoscopic sinus surgery is an effective surgical procedure for treating chronic sinusitis; however, extensive exposure of the bone in the nasal cavity can result in permanent disability postoperatively.
Shun Kikuchi, Tsunetaro Morino, Ryo Takagi, Otori Nobuyoshi, Hiromi Kojima, Masayuki Yamato   +5 more
doaj   +1 more source

Mechanism of TCONS_00147848 regulating apoptosis of nasal mucosa cells and alleviating allergic rhinitis through FOSL2-mediated JAK/STAT3 signaling pathway

Scientific Reports, 2021
This study was conducted to explore the roles and related mechanisms of lncRNA-TCONS_00147848 (TCONS_00147848) in nasal mucosa cell apoptosis and allergic rhinitis (AR).
Haiyun Huang, Yu Ren, Hongyu Liang, Xiaojia Liu, Jisangmo Nan, Hui Zhao, Xiaoling Liu   +6 more
doaj   +1 more source

The nasal symbiont Staphylococcus species restricts the transcription of SARS-CoV-2 entry factors in human nasal epithelium

iScience, 2021
Summary: Emerging evidence indicates that severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is transmitted through the human nasal mucosa via the principal entry factors angiotensin-converting enzyme 2 (ACE2) and transmembrane serine ...
Jeong-Yeon Ji, Ara Jo, Jina Won, Chan Hee Gil, Haeun Shin, Sujin Kim, Yung Jin Jeon, Hyun Jik Kim   +7 more
doaj   +1 more source

A Novel Approach for Investigating Upper Airway Hyperresponsiveness Using Micro-CT in Eosinophilic Upper Airway Inflammation such as Allergic Rhinitis Model

Biomolecules, 2019
Airway hyperresponsiveness (AHR) has been proposed as a feature of pathogenesis of eosinophilic upper airway inflammation such as allergic rhinitis (AR). The measurement system for upper AHR (UAHR) in rodents is poorly developed, although measurements of
Dan Van Bui, Akira Kanda, Yoshiki Kobayashi, Yoshiko Sakata, Yumiko Kono, Yoshiyuki Kamakura, Takao Jinno, Yasutaka Yun, Kensuke Suzuki, Shunsuke Sawada, Mikiya Asako, Akihiko Nakamura, David Dombrowicz, Keita Utsunomiya, Tanigawa Noboru, Koichi Tomoda, Hiroshi Iwai   +16 more
doaj   +1 more source

Effect of Biospray Dressings on Eosinophil Infiltration in the Nasal Mucosa and Serum IgE Levels After Nasal Provocation in Experimental Allergic Rhinitis

Allergy & Rhinology, 2020
Purpose To investigate the effect of biospray dressing on the extent of eosinophil infiltration in the nasal mucosa and the level of serum IgE in experimental allergic rhinitis with nasal provocation.
Shan Huang BSc, Geping Wu MD, PhD, Xiaodan Gu BSM, Hongyan Zhu MD, Xingkai Ma BSM, Yifang Yuan BSM, Yan Lv MD, Di Li MD, Ling Zhang MD   +8 more
doaj   +1 more source

RETRACTED ARTICLE: MicroRNA-29 mediates anti-inflammatory effects and alleviation of allergic responses and symptoms in mice with allergic rhinitis

Allergy, Asthma & Clinical Immunology, 2021
Background To investigate the role of microRNA-29 (miR-29) in mice with allergic rhinitis (AR) and its underlying mechanism. Methods AR model was established in BALB/c mice by intraperitoneal sensitization and intranasal challenge with ovalbumin (OVA ...
Jia Wang, Jinshu Yin, Hong Peng, Aizhu Liu   +3 more
doaj   +1 more source

Neuroregulation of Human Nasal Mucosa [PDF]

Annals of the New York Academy of Sciences, 2009
Multiple subsets of nociceptive, parasympathetic, and sympathetic nerves innervate human nasal mucosa. These play carefully coordinated roles in regulating glandular, vascular, and other processes. These functions are vital for cleaning and humidifying ambient air before it is inhaled into the lungs.
James N. Baraniuk, Samantha Jean Merck
openaire   +3 more sources

Peroxisome Proliferator-Activated Receptor γ Negatively Regulates Allergic Rhinitis in Mice

Allergology International, 2009
Background: Peroxisome proliferator-activated receptor γ (PPAR-γ) has been shown to play an important role in the control of inflammatory responses acting on macrophages, mast cells, T cells, and eosinophils.
Naoko Fukui, Kohei Honda, Eiko Ito, Kazuo Ishikawa   +3 more
doaj   +1 more source

Nasal symbiont Staphylococcus epidermidis restricts the cellular entry of influenza virus into the nasal epithelium

npj Biofilms and Microbiomes, 2022
Our recent study presented that human nasal commensal Staphylococcus epidermidis could potentiate antiviral immunity in the nasal mucosa through interferon-related innate responses. Here, we found that human nasal commensal S.
Ara Jo, Jina Won, Chan Hee Gil, Su Keun Kim, Kang-Mu Lee, Sang Sun Yoon, Hyun Jik Kim   +6 more
doaj   +1 more source

Effects of intranasal administration with Bacillus subtilis on immune cells in the nasal mucosa and tonsils of piglets

Experimental and Therapeutic Medicine, 2018
The nasal mucosa is the body's first barrier against pathogens entering through the respiratory tract. The respiratory immune system of pigs has more similarities with humans than the mouse respiratory system does, and so was selected as the animal model
Yunhan Yang, Yuchao Jing, Jingjing Yang, Qian Yang   +3 more
semanticscholar   +1 more source