Results 31 to 40 of about 602,823 (332)
Characteristics of nasal-associated lymphoid tissue (NALT) and nasal absorption capacity in chicken. [PDF]
PLoS ONE, 2013 As the main mucosal immune inductive site of nasal cavity, nasal-associated lymphoid tissue (NALT) plays an important role in both antigen recognition and immune activation after intranasal immunization.
Haihong Kang +3 more
doaj +1 more source
Lymphocyte Differentiation in the Nasal Mucosa
European Journal of Inflammation, 2007 Few cytological studies have investigated the morphologic changes occurring during lymphocyte differentiation in the nose. The aim of the study is to investigate lymphocyte and plasma cell morphology in patients with allergic rhinitis. Nasal cytology was performed in 110 patients (61 men, 49 women) of ages ranging from 12 to 47 years (mean age, 27 ...
Gelardi M +5 more
openaire +4 more sources
Pharmaceutics, 2018 The blood-brain barrier and the blood-cerebrospinal fluid barrier are major obstacles in central nervous system (CNS) drug delivery, since they block most molecules from entering the brain.
Stella Gänger, K. Schindowski
semanticscholar +1 more source
Burden of Disease in Chronic Rhinosinusitis with Nasal Polyps
Journal of Asthma and Allergy, 2021 Chronic rhinosinusitis with nasal polyps (CRSwNP) is a predominantly type 2 inflammation-mediated disease of the nasal mucosa and paranasal sinuses with an under-recognized clinical, humanistic, and economic burden. Patients with CRSwNP experience a high
C. Bachert +3 more
semanticscholar +1 more source
Operation Nasal Vaccine—Lightning speed to counter COVID-19
Science immunology, 2022 Given the poor ability of intramuscular mRNA COVID-19 vaccines to induce robust immunity in the respiratory mucosa, a push for a nasal vaccine strategy is needed.
E. Topol, A. Iwasaki
semanticscholar +1 more source
Scientific Reports, 2016 Intranasal administration provides a non-invasive drug delivery route that has been proposed to target macromolecules either to the brain via direct extracellular cranial nerve-associated pathways or to the periphery via absorption into the systemic ...
Niyanta N. Kumar +6 more
semanticscholar +1 more source
Different Methods and Formulations of Drugs and Vaccines for Nasal Administration
Pharmaceutics, 2022 Nasal drug delivery is advantageous when compared with other routes of drug delivery as it avoids the hepatic first-pass effect, blood–brain barrier penetration, and compliance issues with parenteral administration. However, nasal administration also has
Junhu Tai +5 more
semanticscholar +1 more source
VASOACTIVE SUBSTANCES IN THE NASAL MUCOSA [PDF]
British Journal of Pharmacology and Chemotherapy, 1958 Besides histamine another smooth muscle stimulating substance has been found in the nasal mucosa of dog and sheep. It is an acid which is readily oxidized by neutral aqueous potassium permanganate and osmium tetroxide, and is thermostable at pH 10·8 but not at pH 2·8.
C. C. Toh, A. Mohiuddin
openaire +3 more sources
An alternative pathway of enteric PEDV dissemination from nasal cavity to intestinal mucosa in swine
Nature Communications, 2018 Porcine epidemic diarrhea virus (PEDV) has catastrophic impacts on the global pig industry. Although the fecal–oral route is generally accepted, an increased number of reports indicate that airborne transmission may contribute to PEDV outbreak.
Yuchen Li +5 more
semanticscholar +1 more source
Alpha-synuclein seeds in olfactory mucosa of patients with isolated REM sleep behaviour disorder.
Brain : a journal of neurology, 2021 Isolated REM sleep behaviour disorder (RBD) is an early-stage α-synucleinopathy in most, if not all, affected subjects. Detection of pathological α-synuclein in peripheral tissues of patients with isolated RBD may identify those progressing to Parkinson ...
A. Stefani +27 more
semanticscholar +1 more source