Results 91 to 100 of about 1,463,832 (396)

Nasopharyngeal carcinoma in Uganda [PDF]

Cancer, 1972
Review of histologic material seen in Uganda over the 5-year period, 1964–1968, revealed 83 cases of nasopharyngeal carcinoma out of a total of 7,000 malignant tumors. All tumors conformed to the anaplastic type, but those with a small cell structure occurred in older men than those made up of larger cells. The histologic appearances of this tumor were
A. C. Templeton, R. Schmauz
openaire   +3 more sources

Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation

Advanced Science, EarlyView.
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang, Jiayue Liu, Min Zhang, Juan Yang, Peihan Lian, Xiu Cheng, Jianhua Qin   +6 more
wiley   +1 more source

Viral hijacking of cellular metabolism. [PDF]

, 2019
This review discusses the current state of the viral metabolism field and gaps in knowledge that will be important for future studies to investigate.
Ch'ng, James, Christofk, Heather R, Thaker, Shivani K   +2 more
core  

Gene Therapy for Pediatric Cancer: State of the Art and Future Perspectives [PDF]

, 2003
While modern treatments have led to a dramatic improvement in survival for pediatric malignancy, toxicities are high and a significant proportion of patients remain resistant.
Biagi, Ettore, Bollard, Catherine, Brenner, Malcolm, Rousseau, Raphael   +3 more
core   +5 more sources

Camrelizumab and apatinib plus induction chemotherapy and concurrent chemoradiotherapy in stage N3 nasopharyngeal carcinoma: a phase 2 clinical trial

Nature Communications
The antiangiogenic agent apatinib has been shown to clinically improve responses to immune checkpoint inhibitors in several cancer types. Patients with N3 nasopharyngeal carcinoma have a high risk of distant metastasis, however, if the addition of ...
Hu Liang, Yao-Fei Jiang, Guo-Ying Liu, Lin Wang, Jian-Wei Wang, Nian Lu, Wei-Xiong Xia, Liang-Ru Ke, Yan-Fang Ye, Jin-Lin Duan, Wei-Xin Bei, Shu-Hui Dong, Wang-Zhong Li, Li-Ting Liu, Chong Zhao, Changqing Xie, Yan-Qun Xiang   +16 more
doaj   +1 more source

Predictive and prognostic role of early apolipoprotein A‐I alteration in recurrent or metastatic nasopharyngeal carcinoma patients treated with anti‐PD‐1 therapy

Cancer Medicine, 2023
Background The primary objective of this study was to evaluate the predictive and prognostic value of serum lipids in recurrent or metastatic nasopharyngeal carcinoma (R/M NPC) patients received anti‐PD‐1 therapy.
Bi Jing Xiao, Xiao Xian Sima, Gang Chen, Haimiti Gulizeba, Ting Zhou, Yan Huang   +5 more
doaj   +1 more source

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

Undifferentiated Carcinoma of Larynx of Nasopharyngeal Type [PDF]

, 2011
Undifferentiated carcinoma of nasopharyngeal type arising in the larynx is unusual. This type of carcinoma-which occurs almost exclusively in nasopharynx-is very infrequent in the larynx (0.2%).
Bansal, S, Gupta, AK, Shankar, A
core   +1 more source

Treatment challenges in and outside a network setting: Head and neck cancers [PDF]

, 2019
Head and neck cancer (HNC) is a rare disease that can affect different sites and is characterized by variable incidence and 5-year survival rates across Europe.
Alfieri S., Almar E., Arveux P., Autelitano M., Baldi I., Bara S., Barchielli A., Benfatto L., Benhamou E., Bento M. J., Bielska-Lasota M., Blaszczyk J., Bordoni A., Botta L., Bouchardy C., Bouvier A. -M., Bouvier V., Brewster D. H., Calleja N., Candela P., Capocaccia R., Carulla M., Clough-Gorr K., Colonna M., Comber H., De Angelis R., de Lacerda G. F., de Munain A. L., Diaz Garcia J. M., Diba C. S., Dimitrova N., Dusek L., Engel J., Ess S. M., Eycken E. V., Falcini F., Ferretti S., Filiberti R. A., Fusco M., Galceran J., Gatta G., Gavin A., Gennaro V., Gentilini M., Giacomin A., Gozdz S., Grosclaude P., Guizard A. -V., Hackl M., Heidrich J., Henau K., Holleczek B., Huws D. W., Iannelli A., Johannesen T. B., Jonasson J. G., Kepska K., Knijn A., Konzelmann I., Kunkler I., Lapotre-Ledoux B., Larranaga N., Leinonen M., Licitra L., Luttmann S., Madeddu A., Magi M., Malila N., Mallone S., Mangone L., Marani E., Marcos-Gragera R., Maspero S., Maynadie M., Mazzoleni G., Michiara M., Miranda A., Molinie F., Monnereau A., Moreno-Iribas C., Mousavi M., Navarro C., Nennecke A., Orlandi E., Pannozzo F., Pierannunzio D., Piffer S., Pildava S., Primic-Zakelj M., Rachtan J., Rashbass J., Ricci P., Robaszkiewic M., Rossi S., Rugge M., Salmeron D., Sanchez M. J., Santaquilani M., Schubert-Fritschle G., Schvartz C., Sekerija M., Sensi F., Serraino D., Simon C., Smailyte G., Spagnoli G., Stabenow R., Stracci F., Sutera Sardo A., Tagliabue G., Tavilla A., Torrella-Ramos A., Trama A., Tretarre B., Troussard X., Tumino R., Usala M., Velten M., Visser O., Vitale F., Woronoff A. -S., Ziino A.   +121 more
core   +1 more source

Genome sequencing analysis identifies Epstein-Barr virus subtypes associated with high risk of nasopharyngeal carcinoma

Nature Genetics, 2019
Epstein–Barr virus (EBV) infection is ubiquitous worldwide and is associated with multiple cancers, including nasopharyngeal carcinoma (NPC). The importance of EBV viral genomic variation in NPC development and its striking epidemic in southern China has
Miao Xu, You-yuan Yao, Hui Chen, Shanshan Zhang, Su-Mei Cao, Zhe Zhang, B. Luo, Zhiwei Liu, Zilin Li, T. Xiang, Guiping He, Qi-sheng Feng, Li Zhen Chen, Xiang Guo, W. Jia, Ming Chen, Xiao Zhang, S. Xie, Roujun Peng, E. Chang, V. Pedergnana, Lin Feng, J. Bei, R. Xu, M. Zeng, W. Ye, H. Adami, Xihong Lin, W. Zhai, Y. Zeng, Jianjun Liu   +30 more
semanticscholar   +1 more source