Results 31 to 40 of about 1,451,429 (415)

Induction chemotherapy in the treatment of nasopharyngeal carcinoma: Clinical outcomes and patterns of care [PDF]

, 2018
The role of induction chemotherapy in nasopharyngeal carcinoma (NPC) remains controversial. The primary aim of this study was to use the National Cancer Database to evaluate the patterns of care of induction chemotherapy in NPC and its impact on overall ...
Adkins, Douglas, Barnes, Justin, Daly, Mackenzie D, Gabani, Prashant, Gay, Hiram A, Lin, Alexander J, Oppelt, Peter, Rich, Jason T, Rudra, Soumon, Thorstad, Wade L, Zevallos, Jose P   +10 more
core   +2 more sources

Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma

Cell Research, 2020
Nasopharyngeal carcinoma (NPC) is an aggressive malignancy with extremely skewed ethnic and geographic distributions. Increasing evidence indicates that targeting the tumor microenvironment (TME) represents a promising therapeutic approach in NPC ...
Yupei Chen, Jianhua Yin, Wen-Fei Li, Hanjie Li, Dong-Ping Chen, Cuijuan Zhang, J. Lv, Ya-Qin Wang, Xiaomin Li, Junyan Li, Panpan Zhang, Yingqin Li, Qingmei He, Xiao-jing Yang, Yuan Lei, Ling-long Tang, G. Zhou, Y. Mao, Chen Wei, Ke-Xu Xiong, Hong-bo Zhang, Shi-da Zhu, Yong Hou, Ying Sun, M. Dean, I. Amit, Kui Wu, D. Kuang, Guibo Li, Na Liu, Jun Ma   +30 more
semanticscholar   +1 more source

Short‐term efficacy and long‐term survival of nasopharyngeal carcinoma patients with radiographically visible residual disease following observation or additional intervention: A real‐world study in China

Laryngoscope Investigative Otolaryngology, 2022
Background To explore the short‐ and long‐term outcomes in patients with nasopharyngeal carcinoma (NPC) with magnetic resonance imaging (MRI)‐detected residual disease at 3 months post‐treatment who received intervention either promptly (0 month) or ...
Ying‐Ying Huang, Xun Cao, Zhuo‐Chen Cai, Jia‐Yu Zhou, Xiang Guo, Xing Lv   +5 more
doaj   +1 more source

Identification of key genes involved in nasopharyngeal carcinoma [PDF]

, 2016
IntroductionNasopharyngeal carcinoma is the most common cancer originating from the nasopharynx.ObjectiveTo study the mechanisms of nasopharyngeal carcinoma, we analyzed GSE12452 microarray data.MethodsGSE12452 was downloaded from the Gene Expression ...
Jiang, Xue, Feng, Lichun, Dai, Baoqiang, Li, Liping, Lu, Weiwei   +4 more
core   +2 more sources

Minimally invasive surgery alone compared with intensity-modulated radiotherapy for primary stage I nasopharyngeal carcinoma

Cancer Communications, 2019
Background The National Comprehensive Cancer Network guidelines recommend intensity-modulated radiotherapy (IMRT) as the primary curative treatment for newly diagnosed nasopharyngeal carcinoma (NPC), but the radiation-related complications and relatively
You-Ping Liu, Xing Lv, Xiong Zou, Yi-Jun Hua, Rui You, Qi Yang, Le Xia, Shao-Yan Guo, Wen Hu, Meng-Xia Zhang, Si-Yuan Chen, Mei Lin, Yu-Long Xie, Li-Zhi Liu, Rui Sun, Pei-Yu Huang, Wei Fan, Xiang Guo, Ming-Huang Hong, Ming-Yuan Chen   +19 more
doaj   +1 more source

Spatial heterogeneity of immune infiltration predicts the prognosis of nasopharyngeal carcinoma patients

OncoImmunology, 2021
Spatial information on the tumor immune microenvironment is of clinical relevance. Here, we aimed to quantify the spatial heterogeneity of lymphocytes and cancer cells and evaluated its prognostic value in patients with nasopharyngeal carcinoma (NPC ...
Ya-Qin Wang, Xu Liu, Cheng Xu, Wei Jiang, Shuo-Yu Xu, Yu Zhang, Ye Lin Liang, Jun-Yan Li, Qian Li, Yu-Pei Chen, Yin Zhao, Jing-Ping Yun, Na Liu, Ying-Qin Li, Jun Ma   +14 more
doaj   +1 more source

A regulatory mutant on TRIM26 conferring the risk of nasopharyngeal carcinoma by inducing low immune response. [PDF]

, 2018
The major histocompatibility complex (MHC) is most closely associated with nasopharyngeal carcinoma (NPC), but the complexity of its genome structure has proven challenging for the discovery of causal MHC loci or genes.
Cheng, Zhi, Dong, Lei, Han, Ming-Yu, Huang, Zhong-Xi, Jiang, Tao, Li, Jin-Bang, Li, Xin, Li, Xin, Liu, Teng-Fei, Liu, Xiao, Long, Xiao-Bing, Lyu, Xiao-Ming, Qiu, Mo-Chang, Sun, Tao, Wang, Jia-Hong, Wang, Jian-Guo, Wang, Qian, Wang, Shuang, Wei, Gan-Guan, Yang, Xue-Xi, Yao, Kaitai, Zhang, Bo, Zhang, Long-Cheng, Zhao, Manli, Zheng, Hou-Feng, Zheng, Lu, Zhu, Xiao-Wei, Zuo, Xian-Bo   +27 more
core   +2 more sources

Nasopharyngeal carcinoma

Current Treatment Options in Oncology, 2002
Nasopharyngeal carcinoma is usually present as locally advanced (stage III or IV) disease. Before 1980, the primary treatment was radiotherapy. The 5-year survival rate of patients with stage IVM0 across the world was less than 30%. Local, regional, and systemic recurrences are high in these patients and contributed to the poor survival.
Muhyi Al Sarraf, Maryada S. Reddy
openaire   +5 more sources

Targeting Epstein-Barr Virus in Nasopharyngeal Carcinoma

Frontiers in Oncology, 2020
Nasopharyngeal carcinoma (NPC) is consistently associated with Epstein-Barr virus (EBV) infection in regions in which it is endemic, including Southern China and Southeast Asia. The high mortality rates of NPC patients with advanced and recurrent disease
P. Hau, H. Lung, Man Wu, C. Tsang, Ka‐Leung Wong, N. Mak, K. Lo   +6 more
semanticscholar   +1 more source

Adding Concurrent Chemotherapy Significantly Improves the Survival of Stage II-IVb Nasopharyngeal Carcinoma Patients Treated With Concurrent Anti-EGFR Agents

Frontiers in Oncology, 2021
ObjectiveAnti-EGFR Targeted agents were found to be capable of modulating the antitumor immunity in head and neck cancer and become more and more frequently used in the treatment of nasopharyngeal carcinoma(NPC).
Zi-Kun Yu, Zi-Kun Yu, Xu-Yin Chen, Xu-Yin Chen, Si-Han Liu, Si-Han Liu, You-Ping Liu, You-Ping Liu, Rui You, Rui You, Pei-Yu Huang, Pei-Yu Huang   +11 more
doaj   +1 more source