Results 31 to 40 of about 1,479,789 (367)

Induction chemotherapy in the treatment of nasopharyngeal carcinoma: Clinical outcomes and patterns of care [PDF]

open access: yes, 2018
The role of induction chemotherapy in nasopharyngeal carcinoma (NPC) remains controversial. The primary aim of this study was to use the National Cancer Database to evaluate the patterns of care of induction chemotherapy in NPC and its impact on overall ...
Adkins, Douglas   +10 more
core   +2 more sources

Alpha-fetoprotein–producing recurrent nasopharyngeal carcinoma: A case report

open access: yesSAGE Open Medical Case Reports, 2021
Alpha-fetoprotein hardly increased due to nasopharyngeal cancer. In this article, we reported a 57-year-old male nasopharyngeal carcinoma patient who had posttreatment subscapular metastasis with high serum alpha-fetoprotein but negative plasma Epstein ...
Zhen-Chong Yang   +7 more
doaj   +1 more source

Increased Angiogenin Expression Correlates With Radiation Resistance and Predicts Poor Survival for Patients With Nasopharyngeal Carcinoma

open access: yesFrontiers in Pharmacology, 2021
Background: Despite the development of such multiple therapeutic approaches, approximately 20% patients experience recurrence. Identification of molecular markers for stratifying the different risks of tumour recurrence and progression is considered ...
Shan-Shan Guo   +22 more
doaj   +1 more source

Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape

open access: yesNature Communications, 2021
Interplay between EBV infection and acquired genetic alterations during nasopharyngeal carcinoma (NPC) development remains vague. Here we report a comprehensive genomic analysis of 70 NPCs, combining whole-genome sequencing (WGS) of microdissected tumor ...
J. Bruce   +31 more
semanticscholar   +1 more source

Circular RNA circRNF13 inhibits proliferation and metastasis of nasopharyngeal carcinoma via SUMO2

open access: yesMolecular Cancer, 2021
Circular RNAs (circRNAs) are widely expressed in human cells and are closely associated with cancer development. However, they have rarely been investigated in the context of nasopharyngeal carcinoma (NPC).
Yongzhen Mo   +19 more
semanticscholar   +1 more source

Nasopharyngeal Carcinoma

open access: yesSurgical Oncology Clinics of North America, 2015
Nasopharyngeal carcinoma is uncommon in the United States, with only 0.2 to 0.5 cases per 100,00 people; this is in contrast to southern China and Hong Kong, where the incidence is 25 to 50 per 100,000 people. There is a potential link between Epstein-Barr virus and the development of nasopharyngeal carcinoma.
Sophia C, Kamran   +2 more
  +9 more sources

Nasopharyngeal carcinoma

open access: yesCurrent Treatment Options in Oncology, 2002
Nasopharyngeal carcinoma is usually present as locally advanced (stage III or IV) disease. Before 1980, the primary treatment was radiotherapy. The 5-year survival rate of patients with stage IVM0 across the world was less than 30%. Local, regional, and systemic recurrences are high in these patients and contributed to the poor survival.
Muhyi Al Sarraf, Maryada S. Reddy
openaire   +5 more sources

Short‐term efficacy and long‐term survival of nasopharyngeal carcinoma patients with radiographically visible residual disease following observation or additional intervention: A real‐world study in China

open access: yesLaryngoscope Investigative Otolaryngology, 2022
Background To explore the short‐ and long‐term outcomes in patients with nasopharyngeal carcinoma (NPC) with magnetic resonance imaging (MRI)‐detected residual disease at 3 months post‐treatment who received intervention either promptly (0 month) or ...
Ying‐Ying Huang   +5 more
doaj   +1 more source

Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma

open access: yesCell Research, 2020
Nasopharyngeal carcinoma (NPC) is an aggressive malignancy with extremely skewed ethnic and geographic distributions. Increasing evidence indicates that targeting the tumor microenvironment (TME) represents a promising therapeutic approach in NPC ...
Yupei Chen   +30 more
semanticscholar   +1 more source

A regulatory mutant on TRIM26 conferring the risk of nasopharyngeal carcinoma by inducing low immune response. [PDF]

open access: yes, 2018
The major histocompatibility complex (MHC) is most closely associated with nasopharyngeal carcinoma (NPC), but the complexity of its genome structure has proven challenging for the discovery of causal MHC loci or genes.
Cheng, Zhi   +27 more
core   +2 more sources

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