Results 111 to 120 of about 29,030 (239)
Annals of Neurology, Volume 99, Issue 2, Page 328-340, February 2026.Objective The growing demand for personalized treatment in multiple sclerosis (MS) highlights the need for more precise biomarkers that can outperform magnetic resonance imaging and clinical assessment in patient stratification. Advances in multiplex proteomic technologies suggest that cerebrospinal fluid (CSF) analysis at MS onset may not only improve
Laura Ghezzi +10 more
wiley +1 more source
The α4β1 homing pathway is essential for ileal homing of Crohn's disease effector T cells in vivo [PDF]
, 2017 The precise mechanisms controlling homing of T effector (Teff) cells to the inflamed gut in Crohn’s disease (CD) are still unclear and clinical outcome data from inflammatory bowel disease (IBD) patients treated with the anti-α4β7 integrin antibody ...
Atreya, Imke +11 more
core +1 more source
Brain and Behavior, Volume 16, Issue 2, February 2026.This study aimed to describe and compare information on diagnoses of MS and related disorders as well as treatments with disease‐modifying therapies (DMTs) available in three national registries, highlighting the key differences relevant to MS research.
Hanna Joensen +3 more
wiley +1 more source
Frontiers in Neurology, 2013 Natalizumab (Tysabri®) is a monoclonal antibody that prevents inflammatory cells from binding to brain endothelial cells and passing into the brain parenchyma.
Hans eLindå, Anders evon Heijne
doaj +1 more source
A Representative Survey of M.S. Patients on Attitudes toward the Benefits and Risks of Drug Therapy [PDF]
, 2006 Background: Although M.S. patients face significant trade-offs between risks and benefits of drug therapy, little is known of their attitudes toward these risks and benefits.
John E. Calfee
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Concomitant granule cell neuronopathy in patients with natalizumab-associated PML [PDF]
, 2016 Granule cell neuronopathy (GCN) is a rare JC virus infection of the cerebellar granule cell neurons in immunocompromised patients. On brain imaging, GCN is characterized by cerebellar atrophy which can be accompanied by infratentorial white matter ...
Eijk, J.J.J. (Jeroen) van +4 more
core +1 more source
Brain and Behavior, Volume 16, Issue 2, February 2026.Comorbidity was present in approximately half of the patients with relapsing‐remitting multiple sclerosis in this Finnish cross‐sectional cohort. Comorbidities, especially psychiatric diseases, were associated with lower persistence on injectable disease‐modifying treatments.
Henrik Ahvenjärvi +4 more
wiley +1 more source
Review: Natalizumab in the treatment of multiple sclerosis
Therapeutic Advances in Neurological Disorders, 2009 Natalizumab reduced the rate of clinical relapse at one year by 68% and the risk of sustained progression of disability by 42—54% over 2 years in its pivotal phase III trial (AFFIRM) in relapsing—remitting multiple sclerosis (RRMS).
Özgür Yaldizli, Norman Putzki
doaj +1 more source
A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis. [PDF]
, 2013 ObjectiveEtrolizumab (rhuMAb β7, anti-β7, PRO145223) is a humanised monoclonal antibody targeting the β7 subunit of the heterodimeric integrins α4β7 and αEβ7, which are implicated in leucocyte migration and retention in ulcerative colitis (UC).
Baumgart, Daniel C +16 more
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Bilateral Idiopathic Pyoderma Gangrenosum: A Case Report of an Atypical Presentation
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT Pyoderma gangrenosum (PG) is a rare non‐infectious neutrophilic dermatosis which is characterized by a rapidly progressive, painful ulcer. Bilateral manifestation of PG is exceptionally rare and can easily be misdiagnosed as infection or vascular ulceration, delaying proper treatment.
Sanjog Thapa Magar +4 more
wiley +1 more source