Results 11 to 20 of about 912 (97)

Heterogeneous clinicopathological findings and patient-reported outcomes in adults with MN1-altered CNS tumors: A case report and systematic literature review

open access: yesFrontiers in Oncology, 2023
The uncommon MN1-altered primary central nervous system (CNS) tumors were recently added to the World Health Organization 2021 classification under the name Astroblastoma, MN1-altered. Another term used to describe them, “High-grade neuroepithelial tumor
Stephen C. Frederico   +23 more
doaj   +1 more source

Recommendations from a Dialogue on Evolving National Cancer Institute-Designated Comprehensive Cancer Center Community Outreach and Engagement Requirements: A Path Forward

open access: yesHealth Equity, 2021
While cancer mortality is declining in the United States, significant racial, ethnic, economic and geographic inequities persist. To help address inequities in cancer treatment, care, support and research, the National Cancer Institute (NCI) instituted ...
doaj   +1 more source

Mechanism of co-operation of mutant IL-7Rα and mutant NRAS in acute lymphoblastic leukemia: role of MYC

open access: yesHaematologica, 2023
Acute lymphoblastic leukemia (ALL) is an aggressive leukemia which can be derived from either T-cell or B-cell precursors. With current treatments, the survival rate is high, but the treatments are highly toxic with severe side effects.
Hila Winer   +6 more
doaj   +1 more source

Evaluation of the frequency and pattern of local recurrence following intersphincteric resection for ultra-low rectal cancer

open access: yesJournal of the Egyptian National Cancer Institute, 2014
Introduction: Abdomino-perineal resection has been the standard treatment for rectal tumors located ⩽5 cm from the anal verge. Recently, intersphincteric resection became a valid option which preserves the bowel continuity with better functional outcome.
W. Abdel-Gawad   +6 more
doaj   +1 more source

Her2/EGFR-PDGFR pathway aberrations associated with tamoxifen response in metastatic breast cancer patients

open access: yesJournal of the Egyptian National Cancer Institute, 2022
Background Metastatic breast cancer (MBC) is a major health problem worldwide. Some patients improve on tamoxifen and others do not respond to treatment.
Ibrahim Malash   +7 more
doaj   +1 more source

Successful use of whole genome amplified DNA from multiple source types for high-density Illumina SNP microarrays

open access: yesBMC Genomics, 2018
Background The recommended genomic DNA input requirements for whole genome single nucleotide polymorphism microarrays can limit the scope of molecular epidemiological studies.
Casey L. Dagnall   +17 more
doaj   +1 more source

Prognostic value of CIP2A gene expression in adult Egyptian acute myeloid leukemia patients

open access: yesEgyptian Journal of Medical Human Genetics, 2020
Background Protein phosphatase 2A (PP2A) functions as a tumor suppressor in many cancers. Cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibits PP2A proteolytic degradation of c-Myc and enhances cell growth and tumor formation in several tissues.
Roxan E. Shafik   +5 more
doaj   +1 more source

Por que as Pesquisas em Oncologia Integrativa são Importantes?

open access: yesRevista Brasileira de Cancerologia, 2013
A Oncologia Integrativa (OI), termo cunhado por Dr. Robert Wittes, diretor da unidade de tratamento e diagnóstico do câncer do National Cancer Institute (NCI), em 2000, é um ramo da Medicina Integrativa que usa práticas alternativas e complementares ...
Pamela Siegel, Nelson Filice de Barros
doaj   +1 more source

Inhibitor of DNA binding proteins revealed as orchestrators of steady state, stress and malignant hematopoiesis

open access: yesFrontiers in Immunology, 2022
Adult mammalian hematopoiesis is a dynamic cellular process that provides a continuous supply of myeloid, lymphoid, erythroid/megakaryocyte cells for host survival.
Shweta Singh   +9 more
doaj   +1 more source

Impact of COVID-19 Pandemic on Medical Practices

open access: yesAsian Pacific Journal of Cancer Care, 2022
The COVID-19 pandemic has affected human life in all spheres. However, the medical and health practices seen changed a lot since the arrival of this pandemic. This article describes the positive and negative impact of covid in the medical field.
Balbir Kumar   +4 more
doaj   +1 more source

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