Results 61 to 70 of about 2,388,117 (306)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Psychological wellbeing, satisfaction with life and optimism in sports managers [PDF]

open access: yes, 2015
In the discourse of its managers, the competitiveness of national sport is increasingly relative, or captive, to the constraints of competitiveness of the respective national economy with an obvious impact on productivity of sports associations and ...
Gonzaga, Luís   +2 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Problem mentality in the context of foreign language education

open access: yesPolylinguality and Transcultural Practices, 2011
This article focuses on the mentality of students registered in the foreign language education. The concept of mentality as the mentality, the mentality of ethnic, national mentality is very widely used in modern scientific categorial apparatus.
N Yu Toursidou
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

UNDERSTANDING THE CONCEPT OF "SPIRITUAL CULTURE" IN CONTEMPORARY CHINESE PHILOSOPHICAL THOUGHT

open access: yesВестник Кемеровского государственного университета, 2014
The paper reflects the views and opinions of modern Chinese philosophers of spiritual culture. Scientists in China analyze spiritual culture as a part of the society's culture.
Zhang Fan
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Н.В. Гоголь о Риме и о римском карнавале

open access: yesИскусство Евразии, 2020
Статья посвящена повести Н.В. Гоголя Рим , в которой воссоздан образ Вечного города 1840-х годов. В слова героя повести молодого римского князя, возвратившегося в Рим из Парижа, писатель вложил свои мысли и эмоциональные впечатления о Риме: о величии ...
Федотова, Елена Дмитриевна
doaj   +1 more source

Exploring the Revenue Mix of Nonprofit Organizations -- Does it Relate to Publicness [PDF]

open access: yes, 2007
Nonprofit organizations offer a wide range of goods and services and seek funding from a variety of revenue sources. Our working theory n this paper is that the sources of funding are related to the services a nonprofit provides - specifically whether ...
Amanda L. Wilsker   +2 more
core   +1 more source

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