Results 121 to 130 of about 4,181,730 (416)

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Factors associated with mortality in persons co-infected with tuberculosis and HIV in Suriname: a retrospective cohort study

Revista Panamericana de Salud Pública, 2019
Objective. To identify socio-demographic and clinical factors associated with mortality among persons with tuberculosis (TB) and TB/HIV co-infection in Suriname. Methods.
Deborah Stijnberg, Eric Commiesie, Diana Marín, Ward Schrooten, Freddy Perez, Mauro Sanchez   +5 more
doaj   +1 more source

A network-based approach for surveillance of occupational health exposures [PDF]

arXiv, 2009
In the context of surveillance of health problems, the research carried out by the French national occupational disease surveillance and prevention network (R\'eseau National de Vigilance et de Pr\'evention des Pathologies Professionnelles, RNV3P) aims to develop, among other approaches, methods of surveillance, statistical analysis and modeling in ...
arxiv  

Time Series Forecasting of HIV/AIDS in the Philippines Using Deep Learning: Does COVID-19 Epidemic Matter? [PDF]

International Journal of Emerging Technology and Advanced Engineering, 12(9), 144-157 (2022)
With a 676% growth rate in HIV incidence between 2010 and 2021, the HIV/AIDS epidemic in the Philippines is the one that is spreading the quickest in the western Pacific. Although the full effects of COVID-19 on HIV services and development are still unknown, it is predicted that such disruptions could lead to a significant increase in HIV casualties ...
arxiv   +1 more source

Advancing Community Health Worker Practice and Utilization: The Focus on Financing [PDF]

, 2006
There is a growing interest in the use of community health workers in various roles in the US health care system. These workers go by various titles and names -- including promotora and community health advisor -- but all assist members of the ...
Catherine Dower, Edward O'Neil, Melissa Knox, Vanessa Lindler   +3 more
core  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Contextual inequalities in specialized dental public health care in Brazil

Brazilian Oral Research
The present study aimed to investigate the contextual inequalities of specialized public dental care (SPDC) in Brazil. The outcome was the trajectory of dental specialized production in municipalities with SPDC (from 2015 to 2017) obtained by group-based
Ana Luiza Cardoso PIRES, Francine dos Santos COSTA, Otávio Pereira D’ÁVILA, Rodrigo Varella de CARVALHO, Marcus Cristian Muniz CONDE, Marcos Britto CORREA, Flávio Fernando DEMARCO, Luiz Alexandre CHISINI   +7 more
doaj   +1 more source

Modeling National Latent Socioeconomic Health and Examination of Policy Effects via Causal Inference [PDF]

arXiv, 2019
This research develops a socioeconomic health index for nations through a model-based approach which incorporates spatial dependence and examines the impact of a policy through a causal modeling framework. As the gross domestic product (GDP) has been regarded as a dated measure and tool for benchmarking a nation's economic performance, there has been a
arxiv  

Methodological reflections on the evaluation of the implementation and adoption of national electronic health record systems [PDF]

, 2012
Copyright @ 2012, International Journal of Integrated Care (IJIC). This work is licensed under a (http://creativecommons.org/licenses/by/3.0) Creative Commons Attribution 3.0 Unported License.Introduction/purpose of presentation: Far-reaching policy ...
Barber, N, Cornford, T, Petrakaki, D, Sheikh, A, Takian, A   +4 more
core   +4 more sources

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source