Results 41 to 50 of about 1,618,479 (311)

Climate Change and Security: Filling Remaining Gaps

Politics and Governance, 2021
As perception of climate change as a threat to humanity and to ecosystems grows, the rapidly growing literature increasingly refers to the notion of “climate change and security,” for which there is as yet no single agreed definition.
Yasuko Kameyama, Yukari Takamura
doaj   +1 more source

No good surprises: intending lecturers' preconceptions and initial experiences of further education [PDF]

, 2002
Current initiatives to promote lifelong learning and a broader inclusiveness in post-16 education have focused attention on further education (FE). The article examines the experiences and reactions of 41 intending lecturers studying full-time for a ...
AlNLEY P., BALL S., BALL S., BANKS I., BLUNKETT D., BREAN S., CAMPBELL J., DEARING R., DELAMONT S., DEPARTMENT FOR EDUCATION &, DEPARTMENT FOR EDUCATION AND EMPLOYMENT, ECO U., FURTHER EDUCATION NATIONAL TRAINING ORGANISATION (FENTO), GOODSON I., LYOTARD J-F., MORAN A., REEVES F., ROGERS C., SHERMAN R., Sue Wallace, WATSON R.   +20 more
core   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Private Governance Responses to Climate Change: The Case of Global Civil Aviation [PDF]

, 2018
This Article explores how private governance can reduce the climate effects of global civil aviation. The civil aviation sector is a major contributor to climate change, accounting for emissions comparable to a top ten emitting country.
Metzger, Daniel J., Vandenbergh, Michael P.   +1 more
core   +2 more sources

Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez, Jill O. Robinson, Wendy A. Allen‐Rhoades, Hadley S. Smith, Isabel Canfield, Rebecca L. Hsu, Sarah R. Scollon, Lauren R. Desrosiers‐Battu, Nicole M. Schneider, Frank Y. Lin, Donald Williams Parsons, Sharon E. Plon, Mary A. Majumder, Janet Malek, Amy L. McGuire   +14 more
wiley   +1 more source

Recent Advances in Reactive Ion Etching and Applications of High-Aspect-Ratio Microfabrication

Micromachines, 2021
This paper reviews the recent advances in reaction-ion etching (RIE) for application in high-aspect-ratio microfabrication. High-aspect-ratio etching of materials used in micro- and nanofabrication has become a very important enabling technology ...
Michael Huff
doaj   +1 more source

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender, Lauren Pommert, Lori R. Backus, Andrea Bidwell, Courtney Blank, Erin H. Breese, Karen C. Burns, Adam Lane, Lynn H. Lee, Benjamin Mizukawa, Robin E. Norris, Maureen M. O'Brien, Daniel Peck, Christine Phillips, Thomas D. Ryan, Jennifer Young, Michael Absalon, John P. Perentesis   +17 more
wiley   +1 more source

Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis

Nature Communications, 2016
HIF-1α is a pivotal protein involved in angiogenesis and is known to be regulated posttranslationally. Here, the authors show that HIF-1α is methylated by Set7/9 methyltransferase, which reduces protein stability and contributes to reduced angiogenesis.
Yunho Kim, Hye Jin Nam, Junyeop Lee, Do Young Park, Chan Kim, Young Suk Yu, Dongha Kim, Se Won Park, Jinhyuk Bhin, Daehee Hwang, Ho Lee, Gou Young Koh, Sung Hee Baek   +12 more
doaj   +1 more source

Motivation of Nurses in Humanitarian and National Initiatives [PDF]

Cross-Cultural Management Journal
The medical professions, particularly nursing and medicine, are driven by dedication, compassion, and a profound sense of mission. Many healthcare professionals extend their contributions beyond their routine duties by volunteering in humanitarian and ...
Milana-Mazal MAZOR
doaj   +1 more source

Citizen Mobilization and Community Institutions: the Public Education Network's Policy Initiatives - Executive Summary [PDF]

, 2006
The executive summary for a report that analyzes the results of a bold set of initiatives designed to stimulate and support public responsibility for public education in 14 locales around the country.
Brenda J. Turnbull
core   +2 more sources