Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Afrocentrism, national interest and citizen welfare in Nigeria's foreign policy maneuvers. [PDF]
F1000Res, 2020 Mbara GC, Gopal N.
europepmc +1 more source
The skills mismatch: what doctoral candidates and employers consider important? [PDF]
, 2011 The mobility of doctorate holders towards the non-academic labor market became of growing interest to policy-makers in and outside academia over the last decade.
De Boyser, Katrien +3 more
core
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
The interest rate sensitivity of Texas industry [PDF]
A key factor in forecasting a region's growth is anticipating how a region will respond to changes in national policy. One important way national policy affects a region is through real interest rates.
Lori L. Taylor, Mine K. Yücel
core
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Integration implementation vector of the national economic interests of Ukraine: theoretical and practical backgrounds aspects [PDF]
International Economic Policy, 2011 In the article there was considered the appropriateness of optimal combining of Ukraine’s economy transparency and policy of economic protectionism for the purpose of its national interest’s defense.
Аndrii Hryshchenko
doaj
National Security And National Interests: Phenomenological Characteristics
The European Proceedings of Social and Behavioural Sciences, 2020 The goal of this article consists in the analysis of phenomenological characteristics and legal correlation of the definitions “national interests” and “national security”. The author highlights doctrinal and conceptual peculiarities of consolidation of national interests in the modern Russian legal system ...
openaire +1 more source
The impact of bank regulations, concentration, and institutions on bank margins [PDF]
This paper examines the impact of bank regulations, concentration, inflation, and national institutions on bank net interest margins using data from over 1,400 banks across 72 countries while controlling for bank-specific characteristics.
Demirguc, Asli +2 more
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source