Results 161 to 170 of about 35,157 (248)

Disruption of ATP Synthase Spatiotemporal Organization, Ca2+ Dynamics, and Contractile Function in Senescent Cardiomyocytes

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Enhanced ATP hydrolysis, ΔΨm flickering, and destabilized ATP synthase dimers collectively reduce ATP availability in senescent cardiomyocytes. This energy deficit is associated with disrupted Ca2⁺ dynamics and contractility. ABSTRACT Heart disease is the leading cause of death in the elderly population.
Silke Morris   +9 more
wiley   +1 more source

Stereoselective total synthesis of (3Z)- and (3E)-elatenynes. [PDF]

open access: yesRSC Adv, 2023
Kwak SY   +7 more
europepmc   +1 more source

PI3Kγ Deficiency Suppresses Cutaneous Squamous Cell Carcinoma Formation by Modulating the Tumour Microenvironment Rather Than by Directly Regulating Keratinocyte Proliferation

open access: yesExperimental Dermatology, Volume 35, Issue 2, February 2026.
ABSTRACT Phosphatidylinositol‐3 kinase (PI3K) is a central regulator of cell proliferation, survival, metabolism, and migration via the downstream AKT/mTOR pathway. Although activating mutations in the catalytic subunit of PI3Kα (p110α) have been documented in various cancers, including cutaneous squamous cell carcinoma (cSCC), the role of PI3Kγ (p110γ)
Aya Toyoshima   +10 more
wiley   +1 more source

The Duration of Caretaker Periods and the Formation of Parliamentary Governments

open access: yesLegislative Studies Quarterly, Volume 51, Issue 1, February 2026.
ABSTRACT In this article, I focus on an understudied aspect of the cabinet formation process in parliamentary democracies: the caretaker periods associated with it. Building on the existing literature on government formation, I discuss conceptualization and measurement of caretaker periods, defined as periods during which a government is no longer or ...
Francesco Bromo
wiley   +1 more source

Late Stage Mannan Metabolism in Cellvibrio japonicus Requires the Combined Action of a Mannosyl‐Glucose Phosphorylase and a Mannobiose Epimerase

open access: yesMolecular Microbiology, Volume 125, Issue 2, Page 173-184, February 2026.
Model for the non‐PTS utilization of manno‐oligosaccharides by Cellvibrio japonicus. The Mgp130A and EpiA enzymes are essential for the utilization of mannose residues. ABSTRACT Manno‐oligosaccharides and their metabolism play important roles in gut health, pharmaceutical development, and renewable chemical production.
Jessica K. Novak, Jeffrey G. Gardner
wiley   +1 more source

Thylakoids reorganization enables driving photosynthesis under far‐red light in the microalga Nannochloropsis gaditana

open access: yesNew Phytologist, Volume 249, Issue 4, Page 1785-1799, February 2026.
Summary Oxygenic photosynthesis is driven by visible light in most photosynthetic organisms, with exceptions in a few cyanobacteria and microalgae species, which can extend the light absorption to far‐red (FR) wavelengths, by synthesizing new pigments or shifting the antennae absorption range beyond 700 nm.
Elisabetta Liistro   +7 more
wiley   +1 more source

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