Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
The Governance and Performance of Research Universities: Evidence from Europe and the U.S. [PDF]
We investigate how university governance affects research output, measured by patenting and international university research rankings. For both European and U.S.
Philippe Aghion +4 more
core
Research, Analysis and Insight into National Standards (RAINS) Project Final Report: National Standards and the Damage Done [PDF]
, 2013 This is the final report of the Research Analysis and Insight into National Standards (RAINS) project, a three-year study of the enactment of the National Standards policy in six diverse primary and intermediate schools.
Thrupp, Martin, White, Michelle
core
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Excellence in Research for Australia 2010: ERA National Report
, 2011 Report on the first national Excellence in Research Australia (ERA) review conducted by the Australian Research Council on research quality of Australian ...
Australian Research Council
core
Management Success Factors of World Class Research Universities
Multidisciplinary Business Review, 2014 This article presents the results of research whose principal purpose was to identify factors affecting the successful performance of research universities. The study examined the highest ranking universities in the Academic Ranking of World Universities
Juan Rock T. +2 more
doaj
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Incentives to Research in European Public Universities [PDF]
In this paper we study the implementation of policy incentives aimed at increasing the research output at European public universities by university managers and public administrations.
Joan Rosselló
core
Research, Analysis and Insight into National Standards (RAINS) Project. First Report: Researching Schools’ Enactments of New Zealand’s National Standards Policy [PDF]
, 2012 This is the first report of the Research, Analysis and Insight into National Standards (RAINS) project, one year into a three-year study of the introduction of National Standards into New Zealand primary and intermediate ...
Easter, Ann, Thrupp, Martin
core