Results 41 to 50 of about 78,970,903 (227)

Evaluation of suitability of substituting wheat flour with sweet potato and tiger nut flours in bread making

Open Agriculture, 2016
The study was carried out to assess the nutritional quality and palatability of bread after partially substituting wheat flour (WF) with sweet potato (SF) and tiger nut (TF) flours.
Ezeocha Chinelo V., Onwuneme Nnenna A.
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Progress in Cassava Research in Uganda - A Technical Report for Project Root Crops - Uganda Phase II

, 1998
This report outlines progress and achievements of the Uganda Root Crops Project phase II covering the period 1991 to 1995. The project enabled Ugandan scientists pursue research aimed at improving the productivity of cassava. Cassava is among the high
Uganda Root Crops Programme, Naari
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Determination of genomic regions associated with early storage root formation and bulking in cassava

Frontiers in Plant Science
Early cassava storage root formation and bulking is a medium of escape that farmers and processors tend to adopt in cases of abiotic and biotic stresses like drought, flood, and destruction by domestic animals.
Simon Peter Abah, Simon Peter Abah, Simon Peter Abah, Joseph Okpani Mbe, Joseph Okpani Mbe, Daniel Kwadjo Dzidzienyo, Damian Njoku, Joseph Onyeka, Eric Yirenkyi Danquah, Samuel Kwane Offei, Samuel Kwane Offei, Peter Kulakow, Chiedozie Ngozi Egesi, Chiedozie Ngozi Egesi   +13 more
doaj   +1 more source

Genotype-by-environment interaction and stability of root mealiness and other organoleptic properties of boiled cassava roots

Scientific Reports, 2022
Genetic enhancement of cassava aimed at improving cooking and eating quality traits is a major goal for cassava breeders to address the demand for varieties that are desirable for the fresh consumption market segment.
Kelechi Uchendu, Damian N. Njoku, Ugochukwu N. Ikeogu, Daniel Dzidzienyo, Pangirayi Tongoona, Samuel Offei, Chiedozie Egesi   +6 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Novel SNP markers and other stress-related genomic regions associated with nitrogen use efficiency in cassava

Frontiers in Plant Science
Cassava productivity is constrained by low soil nitrogen, which is predominant in most cassava-growing regions in the tropics and subtropical agroecology. Improving the low nitrogen tolerance of cassava has become an important breeding objective.
Joseph Okpani Mbe, Joseph Okpani Mbe, Daniel Kwadjo Dzidzienyo, Daniel Kwadjo Dzidzienyo, Simon Peter Abah, Simon Peter Abah, Damian Ndubuisi Njoku, Joseph Onyeka, Pangirayi Tongoona, Chiedozie Egesi, Chiedozie Egesi   +10 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source