Results 21 to 30 of about 33,583 (261)

Cyclic GMP and PKG Signaling in Heart Failure

Frontiers in Pharmacology, 2022
Cyclic guanosine monophosphate (cGMP), produced by guanylate cyclase (GC), activates protein kinase G (PKG) and regulates cardiac remodeling. cGMP/PKG signal is activated by two intrinsic pathways: nitric oxide (NO)-soluble GC and natriuretic peptide (NP)
Genri Numata, Genri Numata, Eiki Takimoto, Eiki Takimoto   +3 more
doaj   +1 more source

Cardiorenal Syndrome in Acute Heart Failure Syndromes

International Journal of Nephrology, 2011
Impaired cardiac function leads to activation of the neurohumoral axis, sodium and water retention, congestion and ultimately impaired kidney function. This sequence of events has been termed the Cardiorenal Syndrome.
Mohammad Sarraf, Robert W. Schrier
doaj   +1 more source

Effect of C-Type Natriuretic Peptide on Maturation and Developmental Competence of Goat Oocytes Matured In Vitro. [PDF]

PLoS ONE, 2015
The developmental competence of oocytes during in vitro maturation (IVM) is compromised due to asynchronous nuclear and cytoplasmic maturation. To improve IVM efficiency, a pre-maturation culture or two-step maturation strategy has been established ...
Junhong Zhang, Qiang Wei, Jiao Cai, Xiaoe Zhao, Baohua Ma   +4 more
doaj   +1 more source

Portopulmonary hypertension practice patterns after liver transplantation

Liver Transplantation, EarlyView., 2022
Abstract Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy after LT and suggest routine echocardiography as ...
Arun Jose, Elizabeth J. Kopras, Shimul A. Shah, Jean M. Elwing   +3 more
wiley   +1 more source

Predictors of acute kidney injury in patients with acute decompensated heart failure in emergency departments in China

Journal of International Medical Research, 2021
Objective This retrospective multicentre observational study was performed to assess the predictors of acute kidney injury (AKI) in patients with acute decompensated heart failure (ADHF) in emergency departments in China.
Hongxia Ge, Yang Liang, Yingying Fang, Yi Jin, Wenting Su, Guoqiang Zhang, Jing Wang, Hui Xiong, Deya Shang, Yanfen Chai, Zhi Liu, Hongyan Wei, Hairong Wang, Wei Zhang, Fei Ma, Wei Zhao, Li Sun, Huan Huang, Qingbian Ma   +18 more
doaj   +1 more source

Mechanisms of vascular aging

Бюллетень сибирской медицины, 2022
Vascular aging plays a key role in morbidity and mortality in the elderly. With age, the vasculature undergoes changes characterized by endothelial dysfunction, wall thickening, decreased elongation, and arterial stiffness. The review focuses on the main
E. M. Stakhneva, E. V. Kashtanova, Ya. V. Polonskaya, V. S. Shramko, Yu. I. Ragino   +4 more
doaj   +1 more source

Atrial natriuretic polypeptide(ANP) as protective agent of renal ischemia.

The Tohoku Journal of Experimental Medicine, 1989
The effect of atrial natriuretic polypeptide (ANP) on hemodynamics and renal function was evaluated after the reconstructive surgery of the left renal artery in a patient with renovascular hypertension secondary to Takayasu's arteritis. The reconstructive surgery was done using the femoral artery, since we were unable to obtain adequate vein segments ...
OMATA, KEN, MATSUI, KUNIAKI, SATO, DAIZO, KAMIOKI, SYUZO, OUTI, HIROSHI, ABE, KEISHI   +5 more
openaire   +3 more sources

Brain natriuretic peptide in pulmonary arterial hypertension: biomarker and potential therapeutic agent

Drug Design, Development and Therapy, 2009
B-type natriuretic peptide (BNP) is a member of the natriuretic peptide family, a group of widely distributed, but evolutionarily conserved, polypeptide mediators that exert myriad cardiovascular effects. BNP is a potent vasodilator with mitogenic, hypertrophic and pro-inflammatory properties that is upregulated in pulmonary hypertensive diseases ...
Brian Casserly, James R Klinger
openaire   +6 more sources

Secondary Publication: Natriuretic Peptides in Heart Failure

Tokyo Women's Medical University Journal
Natriuretic peptides are among the most important discoveries in cardiovascular medicine, revealing the endocrine properties of the heart. Natriuretic peptides are activated in heart failure (HF) and play important cardioprotective roles.
Atsushi Suzuki
doaj   +1 more source

Renal Denervation in Heart Failure: A New Therapeutic Paradigm

Clinical Medicine Insights: Cardiology, 2015
Heart failure constitutes a significant source of morbidity and mortality in the United States, and its incidence and prevalence continue to grow, increasing its burden on the health care system. Renal dysfunction in patients with heart failure is common
Pramesh Dhakal, Kan Liu, Hani Kozman, Daniel Villarreal   +3 more
doaj   +1 more source