Higher serum γKlotho level correlated with the poor prognosis of MVD patients, our predictive model exhibited better predictive ability and clinical usefulness. ABSTRACT Objective This study was aimed at analyzing the correlation of serum γKlotho with the long‐term prognosis of multivessel coronary artery disease (MVD) and develop a predictive model to
Tuersunjiang Naman +8 more
wiley +1 more source
Incremental Value of NT-proBNP Over HCM-AF Score in Risk Stratification for Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy. [PDF]
Gao YP +10 more
europepmc +1 more source
Leptin in Obesity‐Related Heart Failure: Pathophysiological Mechanisms and Therapeutic Implications
Obesity‐associated adipose tissue dysfunction leads to hyperleptinemia and altered leptin signaling. Through Ob‐Rb/LepR‐mediated pathways, leptin may contribute to neurohormonal activation, endothelial dysfunction, inflammation, oxidative stress, and myocardial remodeling.
Xuemin Li +4 more
wiley +1 more source
Risk factors for trastuzumab-induced cardiotoxicity in HER2-positive breast cancer patients. [PDF]
Zhang H, Hu S, Kong N.
europepmc +1 more source
Carfilzomib is highly effective in the treatment of multiple myeloma, but it has been associated with cardiovascular adverse events that impact patient outcomes. Our prior global metabolomic analyses indicated an association between hydrophilic bile acids and carfilzomib‐cardiotoxicity risk, although a causal relationship remained to be determined ...
Samia Shabnaz +15 more
wiley +1 more source
A Narrative Review of Risk Assessment Approaches for Implantable Defibrillator Therapy to Prevent Sudden Cardiac Death in Acute Myocardial Infarction. [PDF]
Kakavand N +6 more
europepmc +1 more source
Patients with severe renal impairment and COVID‐19 are at high risk for severe disease and death. Nirmatrelvir/ritonavir, an antiviral therapy for COVID‐19, is eliminated by renal excretion and can accumulate in patients with severe renal impairment.
Jacqueline Gerhart +7 more
wiley +1 more source
Efficacy of rhBNP in heart failure with atrial fibrillation combined with poor conventional therapy response and recurrence risk factors. [PDF]
Shang H, Wang X, Shi X, Han X.
europepmc +1 more source
Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie +5 more
wiley +1 more source
Invasive Confirmation of Microvascular Recovery Parallel to Left Ventricular Functional Restoration. [PDF]
Toya T +9 more
europepmc +1 more source

