Results 91 to 100 of about 164,451 (332)

Novel mutations in natriuretic peptide receptor-2 gene underlie acromesomelic dysplasia, type maroteaux

BMC Medical Genetics, 2012
Background Natriuretic peptides (NPs) are peptide hormones that exert their biological actions by binding to three types of cell surface natriuretic peptide receptors (NPRs).
Khan Saadullah, Ali Raja, Abbasi Sanaullah, Nawaz Muhammad, Muhammad Noor, Ahmad Wasim   +5 more
doaj   +1 more source

Resveratrol‐Induced Suppression of C‐type Natriuretic Peptide Associates With Increased Vertebral Bone Density in Postmenopausal Women

JBMR Plus, 2023
C‐type natriuretic peptide (CNP) is a paracrine growth factor essential in driving endochondral bone growth in mammals including humans. Despite evidence from animal experiments and tissues that CNP signaling stimulates osteoblast proliferation and ...
Timothy CR Prickett, Peter RC Howe, Eric A Espiner   +2 more
doaj   +1 more source

Predictive Value of Depressive Symptoms for All-Cause Mortality: Findings From the PRIME Belfast Study Examining the Role of Inflammation and Cardiovascular Risk Markers. [PDF]

, 2016
OBJECTIVES: To improve understanding about the potential underlying biological mechanisms in the link between depression and all-cause mortality and to investigate the role that inflammatory and other cardiovascular risk factors may play in the ...
Appleton, Katherine, Blankenberg, S., Donnelly, M., Esquirol, Y., Hughes, M.F., Kee, F., Linden, G., Patterson, C.C., Woodside, J.V., Zeller, T.   +9 more
core   +1 more source

Human C-type natriuretic peptide. Characterization of the gene and peptide. [PDF]

Hypertension, 1992
We isolated the human C-type natriuretic peptide gene and identified the peptide in the brain. The human C-type natriuretic peptide gene appeared to be composed of at least two exons and one intron. In the 5'-flanking region, there is an array of cis elements (an inverted CCAAT box, two GC boxes, and a cyclic AMP response element-like sequence) that is
Y, Ogawa, K, Nakao, O, Nakagawa, Y, Komatsu, K, Hosoda, S, Suga, H, Arai, K, Nagata, N, Yoshida, H, Imura   +9 more
openaire   +2 more sources

C‐type natriuretic peptide in combination with sildenafil attenuates proliferation of rhabdomyosarcoma cells

Cancer Medicine, 2016
Rhabdomyosarcoma (RMS) is a malignant mesenchymal tumor and the most common soft tissue sarcoma in children. Because of several complications associated with intensive multimodal therapies, including growth disturbance and secondary cancer, novel ...
Masahiro Zenitani, T. Nojiri, S. Uehara, K. Miura, H. Hosoda, Toru Kimura, K. Nakahata, M. Miyazato, H. Okuyama, K. Kangawa   +9 more
semanticscholar   +1 more source

Label‐Free Single‐Molecule Immunoassay

Advanced Science, EarlyView.
Label‐free single‐molecule immunoassay (LFSMiA) enables ultra‐sensitive and wide dynamic range protein detection in whole blood samples. LFSMiA features real‐time single‐molecule imaging by plasmonic scattering microscopy, background reduction by a 2‐step sandwich assay, minimizing matrix effect by dynamic tracking of single binding events, and ...
Xiaoyan Zhou, Chao Chen, Shuang Zhou, Guangzhong Ma, Mohammad Javad H. N. Chemerkouh, Christine L. H. Snozek, Eric H. Yang, Jiapei Jiang, Brandyn Braswell, Zijian Wan, Xinyu Zhou, Shaopeng Wang   +11 more
wiley   +1 more source

Foramen magnum stenosis and midface hypoplasia in C-type natriuretic peptide-deficient rats and restoration by the administration of human C-type natriuretic peptide with 53 amino acids.

PLoS ONE, 2019
C-type natriuretic peptide (CNP)-knockout (KO) rats exhibit impaired skeletal growth, with long bones shorter than those in wild-type (WT) rats. This study compared craniofacial morphology in the CNP-KO rat with that in the Spontaneous Dwarf Rat (SDR), a
Takafumi Yotsumoto, Naomi Morozumi, Mayumi Furuya, Toshihito Fujii, Keisho Hirota, Yohei Ueda, Kazumasa Nakao, Shigeki Yamanaka, Kazunori Yoshikiyo, Sayaka Yoshida, Tomonari Nishimura, Yasuyuki Abe, Toshimasa Jindo, Hiroyuki Ogasawara, Akihiro Yasoda   +14 more
doaj   +1 more source

GUANYLYL CYCLASE/NATRIURETIC PEPTIDES RECEPTOR-A SIGNALING ANTAGONIZES PHOSPHOINOSITIDE HYDROLYSIS, Ca2+ RELEASE, AND ACTIVATION OF PROTEIN KINASE C

Frontiers in Molecular Neuroscience, 2014
Thus far, three related natriuretic peptides (NPs) and three distinct sub-types of cognate NP receptors have been identified and characterized based on the specific ligand binding affinities, guanylyl cyclase activity, and generation of intracellular ...
Kailash N Pandey
doaj   +1 more source

Elevated C-type natriuretic peptide elicits exercise preconditioning-induced cardioprotection against myocardial injury probably via the up-regulation of NPR-B

Journal of Physiological Sciences, 2016
To evaluate exercise preconditioning (EP)-induced cardioprotective effects against exercise-induced acute myocardial injury and investigate the alterations of C-type natriuretic peptide (CNP) and its specific receptor, natriuretic peptide receptor B (NPR-
Jiao Lu, S. Pan
semanticscholar   +1 more source

Doped Zinc Oxide‐Based Piezoelectric Devices for Energy Harvesting and Sensing

Advanced Energy and Sustainability Research, EarlyView.
This review provides a comprehensive overview of material properties, synthesis methods, and characterization techniques of doped ZnO, emphasizing the impact of doping on its structural and functional attributes. It highlights key findings, identifies knowledge gaps, and proposes future research directions to optimize doped ZnO for energy harvesting ...
Congran Jin, Junhu Zhou, Ziqian Wu, John X. J. Zhang   +3 more
wiley   +1 more source