Results 231 to 240 of about 69,627 (265)

C-type natriuretic peptide system in rabbit oviduct

Peptides, 2001
C-type natriuretic peptide (CNP), a third member of the natriuretic peptide family, is known to be distributed mainly in brain and vascular endothelium and is considered to act as a local regulator in many tissues. The purpose of this study was to determine the presence of CNP system and its biological function in rabbit oviduct.
S H, Kim, K S, Lee, S J, Lee, K H, Seul, S Z, Kim, K W, Cho   +5 more
openaire   +2 more sources

C-TYPE NATRIURETIC PEPTIDE (CNP) IN RATS AND HUMANS

Endocrinology, 1991
We have established a specific radioimmunoassay (RIA) for C-type natriuretic peptide (CNP), the third member of the natriuretic peptide family, and have elucidated its tissue distribution and molecular form. In rats, high concentrations of CNP-like immunoreactivity (-LI) were detected in the anterior lobe (19.8 +/- 8.6 pmol/g) and neurointermediate ...
Yasato Komatsu, Kazuwa Nakao, Shin-ichi Suga, Yoshihiro Ogawa, Masashi Mukoyama, Hiroshi Arai, Gotaro Shirakami, Kiminori Hosoda, Osamu Nakagawa, Norio Hama, Ichiro Kishimoto, Hiroo Imura   +11 more
openaire   +2 more sources

Detection of C-type natriuretic peptide in fetal circulation

Journal of Perinatal Medicine, 2000
C-type natriuretic peptide (CNP) belongs to the natriuretic peptide family that plays an important role in the control of blood pressure, renal function and volume homeostasis. In contrast to the atrial natriuretic peptide and brain natriuretic peptide, CNP acts in an autocrine/paracrine fashion and is considered to be the endothelial component of the ...
H, Stepan, D, Walther, R, Faber, T, Walther   +3 more
openaire   +2 more sources

C-type natriuretic peptide in vascular physiology and disease

Pharmacology & Therapeutics, 2005
Natriuretic peptides play a critical role in coordination of fluid/electrolyte balance and vascular tone. The renal effects of circulating atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) are distinct from the paracrine effects of vascular C-type natriuretic peptide (CNP).
Ramona S, Scotland, Amrita, Ahluwalia, Adrian J, Hobbs   +2 more
openaire   +2 more sources

C-type natriuretic peptide system in rabbit colon

Peptides, 2001
C-type natriuretic peptide (CNP) is mainly distributed in the brain and vascular endothelium and is considered to act as a local regulator in many tissues. The present study was aimed to determine the presence of CNP system and its biological function in rabbit colon.
J H, Kim, G J, Jeon, S Z, Kim, K W, Cho, S H, Kim   +4 more
openaire   +2 more sources

C-type natriuretic peptide: the endothelial component of the natriuretic peptide system.

Journal of cardiovascular pharmacology, 1999
C-type natriuretic peptide (CNP) is a 22-amino-acid peptide, structurally related to but genetically distinct from atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP). Whereas ANP and BNP are ligands for a guanylyl cyclase-coupled receptor, the NPR-A receptor, CNP is a specific ligand for the NPR-B receptor. In addition to clearance by
H H, Chen, J C, Burnett
openaire   +1 more source

Brain Natriuretic Peptide and C‐Type Natriuretic Peptide Maintain Porcine Oocyte Meiotic Arrest

Journal of Cellular Physiology, 2014
Recent studies have shown that C‐type natriuretic peptide (CNP) serves as a key control system during mouse oocyte maturation. We used pig models (in vitro and in vivo) to explore the role played by the natriuretic peptide family in porcine oocyte maturation.
Wenqiang, Zhang, Ye, Yang, Wei, Liu, Qian, Chen, Huarong, Wang, Xiao, Wang, Yanhao, Zhang, Meijia, Zhang, Guoliang, Xia   +8 more
openaire   +2 more sources

C-type natriuretic peptide in growth: A new paradigm

Growth Hormone & IGF Research, 2006
C-type natriuretic peptide (CNP), acting through its receptor, natriuretic peptide receptor-B (NPR-B), plays a critical role in linear growth. Knockout mice for CNP and NPR-B are dwarfed, and transgenic mice overexpressing CNP are overgrown. CNP has a direct regulatory effect on growth plate chondrocytes, acting primarily to promote terminal ...
openaire   +2 more sources

C-Type Natriuretic Peptide Analog as Therapy for Achondroplasia

2015
Fibroblast growth factor receptor 3 (FGFR3) is an important regulator of bone formation. Gain-of-function mutations in the FGFR3 gene result in chondrodysplasias which include achondroplasia (ACH), the most common form of dwarfism, in which skull, appendicular and axial skeletons are affected.
openaire   +2 more sources

[Comparison of vasorelaxing actions of vasonatrin peptide, C-type natriuretic peptide and atrial natriuretic peptide].

Sheng li xue bao : [Acta physiologica Sinica], 2001
The vasorelaxing effects of vasonatrin peptide (VNP), C-type natriuretic peptide (CNP) and atrial natriuretic peptide (ANP) on isolated rat pulmonary artery, abdominal aorta and celiac vein were measured by in vitro perfusion. The results showed that VNP, CNP and ANP caused concentration-dependent relaxation in isolated rat pulmonary artery, abdominal ...
H S, Feng, Y M, Zang, M Z, Zhu, J M, Pei, Y M, Wang, L, Wang, P T, Shi   +6 more
openaire   +1 more source