Results 11 to 20 of about 1,178,486 (216)

Inflammation and circulating natriuretic peptide levels

Circulation: Heart Failure, 2020
Supplemental Digital Content is available in the text. Background: NPs (natriuretic peptides) are cardiac-derived hormones that promote natriuresis, diuresis, and vasodilation.
Hannah L. Fish-Trotter, Jane F. Ferguson, Nirav Patel, Pankaj Arora, N. Allen, Katherine N. Bachmann, L. Daniels, M. Reilly, J. Lima, Thomas J. Wang, D. Gupta   +10 more
semanticscholar   +1 more source

Pathogenetic justification of sacubitril / valsartan use in respiratory-cardial comorbidity

Patologìâ, 2023
Among the comorbid conditions that significantly worsen quality of life and life expectancy are the chronic obstructive pulmonary disease and heart failure.
T. V. Ashcheulova, K. M. Kompaniiets, N. M. Herasymchuk, I. V. Sytina   +3 more
doaj   +1 more source

zDHHC9 Regulates Cardiomyocyte Rab3a Activity and Atrial Natriuretic Peptide Secretion Through Palmitoylation of Rab3gap1

JACC: Basic to Translational Science, 2023
Summary: Production and release of natriuretic peptides by the stressed heart reduce cardiac workload by promoting vasodilation, natriuresis, and diuresis, which has been leveraged in the recent development of novel heart-failure pharmacotherapies, yet ...
Kobina Essandoh, PhD, Arasakumar Subramani, MS, Olivia A. Ferro, MS, James P. Teuber, BS, Sribharat Koripella, Matthew J. Brody, PhD   +5 more
doaj   +1 more source

Natriuretic peptides: Diagnostic and therapeutic use

Indian Journal of Endocrinology and Metabolism, 2011
Natriuretic peptides (NPs) are hormones which are mainly secreted from heart and have important natriuretic and kaliuretic properties. There are four different groups NPs identified till date [atrial natriuretic peptide (ANP), B-type natriuretic peptide (
Kaushik Pandit, Pradip Mukhopadhyay, Sujoy Ghosh, Subhankar Chowdhury   +3 more
doaj   +1 more source

Heart Failure Association of the European Society of Cardiology practical guidance on the use of natriuretic peptide concentrations

European Journal of Heart Failure, 2019
Natriuretic peptide [NP; B‐type NP (BNP), N‐terminal proBNP (NT‐proBNP), and midregional proANP (MR‐proANP)] concentrations are quantitative plasma biomarkers for the presence and severity of haemodynamic cardiac stress and heart failure (HF).
C. Mueller, K. McDonald, R. de Boer, A. Maisel, J. Cleland, N. Kozhuharov, A. Coats, M. Metra, A. Mebazaa, F. Ruschitzka, M. Lainščak, G. Filippatos, P. Seferovic, W. Meijers, A. Bayés‐Genís, T. Mueller, M. Richards, J. Januzzi   +17 more
semanticscholar   +1 more source

Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide.

Endocrinology, 1992
To elucidate the ligand-receptor relationship of the natriuretic peptide system, which comprises at least three endogenous ligands, atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP), and three receptors, the ANP-A receptor or guanylate cyclase-A (GC-A), the ANP-B receptor or guanylate cyclase-B (GC ...
S, Suga, K, Nakao, K, Hosoda, M, Mukoyama, Y, Ogawa, G, Shirakami, H, Arai, Y, Saito, Y, Kambayashi, K, Inouye   +9 more
openaire   +5 more sources

B-type Natriuretic Peptide During Treatment with Sacubitril/Valsartan: the PARADIGM-HF Trial

Journal of the American College of Cardiology, 2019
STRUCTURED ABSTRACT Background: Natriuretic peptides are substrates of neprilysin; hence B-type natriuretic peptide (BNP) concentrations rise with neprilysin inhibition.
P. Myhre, M. Vaduganathan, B. Claggett, M. Packer, Akshay S. Desai, J. Rouleau, M. Zile, K. Swedberg, M. Lefkowitz, V. Shi, J. McMurray, S. Solomon   +11 more
semanticscholar   +1 more source

Natriuretic Peptides

Journal of the American College of Cardiology, 2007
Natriuretic peptides (NPs) are released from the heart in response to pressure and volume overload. B-type natriuretic peptide (BNP) and N-terminal-proBNP have become important diagnostic tools for assessing patients who present acutely with dyspnea. The NP level reflects a compilation of systolic and diastolic function as well as right ventricular and
Daniels, Lori B., Maisel, Alan S.
openaire   +2 more sources

Brain natriuretic peptide-expressing sensory neurons are not involved in acute, inflammatory, or neuropathic pain

Molecular Pain, 2017
Background We recently demonstrated that brain natriuretic peptide is expressed in the dorsal root ganglia, and that brain natriuretic peptide is required for normal detection of pruritogens.
Saumitra Pitake, Jennifer DeBrecht, Santosh K Mishra   +2 more
doaj   +1 more source

C-Type Natriuretic Peptide: A Multifaceted Paracrine Regulator in the Heart and Vasculature

International Journal of Molecular Sciences, 2019
C-type natriuretic peptide (CNP) is an autocrine and paracrine mediator released by endothelial cells, cardiomyocytes and fibroblasts that regulates vital physiological functions in the cardiovascular system.
A. Moyes, A. Hobbs
semanticscholar   +1 more source