Results 21 to 30 of about 102,706 (265)

B-type natriuretic peptide predicts long-term prognosis in a cohort of critically Ill patients

Heart International, 2011
B-type natriuretic peptide is an important prognostic marker in heart failure. However, there are limited data for its value in non-cardiac intensive care unit patients, namely regarding long-term prognosis. We investigated the long-term prognostic value
Jorge Pimentel, Eduardo Sousa, Elisabete Jorge, Rui Baptista   +3 more
doaj   +1 more source

Physiology and clinical significance of natriuretic hormones

Indian Journal of Endocrinology and Metabolism, 2013
The natriuretic system consists of the atrial natriuretic peptide (ANP) and four other similar peptides including the wrongly named brain natriuretic peptide (BNP). Chemically they are small peptide hormones predominantly secreted by the cardiac myocytes
Sandeep Chopra, Davis Cherian, Prashant Paul Verghese, Jubbin J Jacob   +3 more
doaj   +1 more source

Inefficient constitutive inhibition of P2X3 receptors by brain natriuretic peptide system contributes to sensitization of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine

Molecular Pain, 2016
Background On trigeminal ganglion neurons, pain-sensing P2X3 receptors are constitutively inhibited by brain natriuretic peptide via its natriuretic peptide receptor-A. This inhibition is associated with increased P2X3 serine phosphorylation and receptor
Anna Marchenkova PhD, Sandra Vilotti PhD, Niels Ntamati MS, Arn MJM van den Maagdenberg PhD, Andrea Nistri MD   +4 more
doaj   +1 more source

Natriuretic Peptide-Based Novel Therapeutics: Long Journeys of Drug Developments Optimized for Disease States

Biology, 2022
The field of natriuretic peptides (NPs) as an endocrine hormone has been developing since 1979. There are three peptides in humans: atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP), which bind to the guanylyl cyclase-A (GC-A ...
Tomoko Ichiki, Atsushi Jinno, Yoshihisa Tsuji   +2 more
doaj   +1 more source

Changes in Serum Natriuretic Peptide Levels after Percutaneous Closure of Small to Moderate Ventricular Septal Defects

The Scientific World Journal, 2012
Background. B-type natriuretic peptide has been shown to be a very sensitive and specific marker of heart failure. In this study, we aimed to investigate the effect of percutaneous closure of ventricular septal defects with Amplatzer septal occluders on ...
Yuksel Kaya, Ramazan Akdemir, Huseyin Gunduz, Sani Murat, Orhan Bulut, İbrahim Kocayigit, M. Bulent Vatan, M. Akif Cakar, Ekrem Yeter, Harun Kilic, Mustafa Tarik Agac, Zeydin Acar   +11 more
doaj   +1 more source

Plasma brain natriuretic peptide as a surrogate marker for cardioembolic stroke

BMC Neurology, 2008
Background Cardioembolic stroke generally results in more severe disability, since it typically has a larger ischemic area than the other types of ischemic stroke.
Dobashi Hiroaki, Nakamura Takehiro, Ueno Masaki, Murao Koji, Masugata Hisashi, Mukai Mao, Ohkita Hiroyuki, Takahashi Tsutomu, Naya Takayuki, Hosomi Naohisa, Yukiiri Kazushi, Miki Takanori, Kuroda Yasuhiro, Kohno Masakazu   +13 more
doaj   +1 more source

Do N-Terminal Pro-C-Type Natriuretic Peptide Levels Relate to Severity of Preeclampsia?

International Journal of Hypertension, 2020
Aim. To compare the plasma N-terminal pro-C-type natriuretic peptide concentrations of normotensive pregnant women, patients with mild preeclampsia, and patients with severe preeclampsia. Methods.
Dogan Vatansever, Pınar Vatansever, Burak Giray, A. Aktug Ertekin, Serpil Bilsel   +4 more
doaj   +1 more source

Artificial Intelligence-Enabled Electrocardiography Detects B-Type Natriuretic Peptide and N-Terminal Pro-Brain Natriuretic Peptide

Diagnostics, 2023
BACKGROUND: The B-type natriuretic peptide (BNP) and N-terminal pro-brain natriuretic peptide (pBNP) are predictors of cardiovascular morbidity and mortality. Since the artificial intelligence (AI)-enabled electrocardiogram (ECG) system is widely used in
Pang-Yen Liu, Chin Lin, Chin-Sheng Lin, Wen-Hui Fang, Chia-Cheng Lee, Chih-Hung Wang, Dung-Jang Tsai   +6 more
doaj   +1 more source

Taipan Natriuretic Peptides Are Potent and Selective Agonists for the Natriuretic Peptide Receptor A

Molecules, 2023
Cardiovascular ailments are a major cause of mortality where over 1.3 billion people suffer from hypertension leading to heart-disease related deaths. Snake venoms possess a broad repertoire of natriuretic peptides with therapeutic potential for treating hypertension, congestive heart failure, and related cardiovascular disease. We now describe several
Simone Vink, Kalyana Bharati Akondi, Jean Jin, Kim Poth, Allan M. Torres, Philip W. Kuchel, Sandra L. Burke, Geoffrey A. Head, Paul F. Alewood   +8 more
openaire   +6 more sources

AC-NP: a novel chimeric peptide with natriuretic and vasorelaxing actions. [PDF]

PLoS ONE, 2011
The aim of this study was to evaluate the cardiovascular and renal activities of a newly designed natriuretic peptide (NP). Here, we engineered a novel 28-amino acid chimeric peptide, termed AC-NP that combined the 17-amino acid ring of C type ...
Bao-Ying Chen, Jian-Kang Chen, Miao-Zhang Zhu, Dong-Liang Zhang, Jie-Shen Sun, Jian-Ming Pei, Hua-Song Feng, Xiao-Xing Zhu, Jian Jin, Jun Yu   +9 more
doaj   +1 more source