Results 31 to 40 of about 990,536 (371)

Resetting the neurohormonal balance in heart failure (HF). the relevance of the natriuretic peptide (NP) system to the clinical management of patients with HF [PDF]

open access: yes, 2017
The natriuretic peptide (NP) system, which includes atrial natriuretic peptide, B-type natriuretic peptide, and C-type natriuretic peptide, has an important role in cardiovascular homeostasis, promoting a number of physiological effects including ...
Rubattu, Speranza Donatella   +1 more
core   +2 more sources

Cardiovascular Pleiotropic Effects of Natriuretic Peptides

open access: yesInternational Journal of Molecular Sciences, 2019
Atrial natriuretic peptide (ANP) is a cardiac hormone belonging to the family of natriuretic peptides (NPs). ANP exerts diuretic, natriuretic, and vasodilatory effects that contribute to maintain water–salt balance and regulate blood pressure.
Maurizio Forte   +7 more
semanticscholar   +1 more source

Natriuretic Peptides: The Case of Prostate Cancer

open access: yesMolecules, 2017
Cardiac natriuretic peptides have long been known to act as main players in the homeostatic control of blood pressure, salt and water balance. However, in the last few decades, new properties have been ascribed to these hormones.
Letizia Mezzasoma   +3 more
doaj   +1 more source

Blockade of the natriuretic peptide clearance receptor attenuates proteinuria in a mouse model of focal segmental glomerulosclerosis

open access: yesPhysiological Reports, 2021
Glomerular podocytes play a key role in proteinuric diseases. Accumulating evidence suggests that cGMP signaling has podocyte protective effects. The major source of cGMP generation in podocytes is natriuretic peptides.
Liming Wang   +3 more
doaj   +1 more source

Natriuretic Peptides in Heart Failure with Preserved Left Ventricular Ejection Fraction: From Molecular Evidences to Clinical Implications

open access: yesInternational Journal of Molecular Sciences, 2019
The incidence of heart failure with preserved ejection fraction (HFpEF) is increasing and its challenging diagnosis and management combines clinical, imagistic and biological data.
D. Tănase   +7 more
semanticscholar   +1 more source

NT-proBNP as a predictor of death and cardiovascular events in patients with type 2 diabetes

open access: yesDiabetology & Metabolic Syndrome, 2022
Existing risk prediction scores based on clinical and laboratory variables have been considered inaccurate in patients with Type 2 Diabetes Mellitus (T2DM).
Marcus Vinicius Bolivar Malachias   +2 more
doaj   +1 more source

Effects of sacubitril/valsartan on neprilysin targets and the metabolism of natriuretic peptides in chronic heart failure: a mechanistic clinical study

open access: yesEuropean Journal of Heart Failure, 2018
This study aimed at evaluating the effects of sacubitril/valsartan on neprilysin (NEP), and the metabolism of natriuretic peptides in heart failure (HF) and providing additional mechanistic information on the mode of action of the drug.
H. Nougué   +9 more
semanticscholar   +1 more source

Physiology and clinical significance of natriuretic hormones

open access: yesIndian Journal of Endocrinology and Metabolism, 2013
The natriuretic system consists of the atrial natriuretic peptide (ANP) and four other similar peptides including the wrongly named brain natriuretic peptide (BNP). Chemically they are small peptide hormones predominantly secreted by the cardiac myocytes
Sandeep Chopra   +3 more
doaj   +1 more source

Molecular Implications of Natriuretic Peptides in the Protection from Hypertension and Target Organ Damage Development

open access: yesInternational Journal of Molecular Sciences, 2019
The pathogenesis of hypertension, as a multifactorial trait, is complex. High blood pressure levels, in turn, concur with the development of cardiovascular damage.
S. Rubattu   +3 more
semanticscholar   +1 more source

Synthesis, secretion, function, metabolism and application of natriuretic peptides in heart failure

open access: yesJournal of Biological Engineering, 2018
As a family of hormones with pleiotropic effects, natriuretic peptide (NP) system includes atrial NP (ANP), B-type NP (BNP), C-type NP (CNP), dendroaspis NP and urodilatin, with NP receptor-A (guanylate cyclase-A), NP receptor-B (guanylate cyclase-B) and
S. Fu, P. Ping, Fengqi Wang, L. Luo
semanticscholar   +1 more source

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