Results 11 to 20 of about 25,222 (258)

Natriuretic Peptides and Metabolic Hypertension [PDF]

JACC: Basic to Translational Science
Jens P. Goetze, MD, DMSc, Jens F. Rehfeld, MD, DMSc   +1 more
doaj   +2 more sources

Natriuretic peptides appeared after their receptors in vertebrates

BMC Evolutionary Biology, 2019
Background In mammals, the natriuretic system contains three natriuretic peptides, NPPA, NPPB and NPPC, that bind to three transmembrane receptors, NPR1, NPR2 and NPR3. The natriuretic peptides are known only in vertebrates.
Anna Grandchamp, Shifa Tahir, Philippe Monget   +2 more
doaj   +1 more source

Modified natriuretic peptides and their potential roles in cancer treatment

Biomedical Journal, 2022
The natriuretic peptide family (NPs) is a group of natural endocrine hormones, containing a 17-amino acid ring structure connected by disulfide bonds of two cysteines.
Mengjiao Xu, Xingzhu Liu, Ping Li, Yadong Yang, Wenyuan Zhang, Siyu Zhao, Ying Zeng, Xile Zhou, Ling-hui Zeng, Geng Yang   +9 more
doaj   +1 more source

Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide.

Endocrinology, 1992
To elucidate the ligand-receptor relationship of the natriuretic peptide system, which comprises at least three endogenous ligands, atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP), and three receptors, the ANP-A receptor or guanylate cyclase-A (GC-A), the ANP-B receptor or guanylate cyclase-B (GC ...
S, Suga, K, Nakao, K, Hosoda, M, Mukoyama, Y, Ogawa, G, Shirakami, H, Arai, Y, Saito, Y, Kambayashi, K, Inouye   +9 more
openaire   +5 more sources

Natriuretic Peptides: Biochemistry, Physiology, Clinical Implication

Общая реаниматология, 2009
In the past years, the interest of theorists and clinicians has steadily increased in the myocardially secreted hormones – natriuretic peptides. At the Congress of the European Society of Anesthesiology (Munich, 2007), B-type natriuretic peptides ...
I. A. Kozlova, I. Ye. Kharlamova
doaj   +1 more source

Natriuretic Peptides

Journal of the American College of Cardiology, 2007
Natriuretic peptides (NPs) are released from the heart in response to pressure and volume overload. B-type natriuretic peptide (BNP) and N-terminal-proBNP have become important diagnostic tools for assessing patients who present acutely with dyspnea. The NP level reflects a compilation of systolic and diastolic function as well as right ventricular and
Daniels, Lori B., Maisel, Alan S.
openaire   +2 more sources

INTEGRATION OF BIOMARKERS INTO THE PRACTICE OF TREATING PATIENTS WITH HEART FAILURE: THE ROLE OF DETERMINING THE BLOOD LEVEL OF NATRIURETIC PEPTIDES

Рациональная фармакотерапия в кардиологии, 2017
A clinical role of biomarkers (especially, natriuretic peptides) is discussed in the article. The most important evidences of clinical effectiveness of using biomarkers in patients with suspected heart failure and in patients with confirmed diagnose of ...
S. R. Gilyarevskiy, M. V. Golshmid, I. M. Kuzmina   +2 more
doaj   +1 more source

Evidence-Based Application of Natriuretic Peptides in the Evaluation of Chronic Heart Failure With Preserved Ejection Fraction in the Ambulatory Outpatient Setting [PDF]

Circulation
Yogesh Reddy, Ryan J Tedford, Barry Borlaug   +2 more
exaly   +2 more sources

Designer Natriuretic Peptides [PDF]

Journal of Investigative Medicine, 2009
Designer natriuretic peptides (NPs) are novel hybrid peptides that are engineered from the native NPs through addition, deletion, or substitution of amino acid(s) with a goal toward optimization of pharmacological actions while minimizing undesirable effects.
Candace Y W, Lee, Hsiao, Lieu, John C, Burnett   +2 more
openaire   +2 more sources

Neprilysin Inhibitors in Heart Failure

JACC: Basic to Translational Science, 2023
Summary: This article provides a contemporary review and a new perspective on the role of neprilysin inhibition in heart failure (HF) in the context of recent clinical trials and addresses potential mechanisms and unanswered questions in certain HF ...
Biykem Bozkurt, MD, PhD, Ajith P. Nair, MD, Arunima Misra, MD, Claire Z. Scott, MD, Jamal H. Mahar, MD, Savitri Fedson, MD, MA   +5 more
doaj   +1 more source