Results 31 to 40 of about 29,778 (296)

Natriuretic Peptides

Journal of the American College of Cardiology, 2007
Natriuretic peptides (NPs) are released from the heart in response to pressure and volume overload. B-type natriuretic peptide (BNP) and N-terminal-proBNP have become important diagnostic tools for assessing patients who present acutely with dyspnea. The NP level reflects a compilation of systolic and diastolic function as well as right ventricular and
Daniels, Lori B., Maisel, Alan S.
openaire   +2 more sources

Designer Natriuretic Peptides [PDF]

Journal of Investigative Medicine, 2009
Designer natriuretic peptides (NPs) are novel hybrid peptides that are engineered from the native NPs through addition, deletion, or substitution of amino acid(s) with a goal toward optimization of pharmacological actions while minimizing undesirable effects.
Candace Y W, Lee, Hsiao, Lieu, John C, Burnett   +2 more
openaire   +2 more sources

INTEGRATION OF BIOMARKERS INTO THE PRACTICE OF TREATING PATIENTS WITH HEART FAILURE: THE ROLE OF DETERMINING THE BLOOD LEVEL OF NATRIURETIC PEPTIDES

Рациональная фармакотерапия в кардиологии, 2017
A clinical role of biomarkers (especially, natriuretic peptides) is discussed in the article. The most important evidences of clinical effectiveness of using biomarkers in patients with suspected heart failure and in patients with confirmed diagnose of ...
S. R. Gilyarevskiy, M. V. Golshmid, I. M. Kuzmina   +2 more
doaj   +1 more source

Atrial natriuretic factor [PDF]

, 1987
The discovery of the first well-defined natriuretic hormone, the Atrial Natriuretic Factor (ANF), has prompted research on its impact on volume regulation in health and disease.
Arendt, Rainer M., Paumgartner, Gustav, Morris, Mariana, Gerbes, Alexander L., Buckalew, V M, Hamilton, R W   +5 more
core   +1 more source

Neprilysin Inhibitors in Heart Failure

JACC: Basic to Translational Science, 2023
Summary: This article provides a contemporary review and a new perspective on the role of neprilysin inhibition in heart failure (HF) in the context of recent clinical trials and addresses potential mechanisms and unanswered questions in certain HF ...
Biykem Bozkurt, MD, PhD, Ajith P. Nair, MD, Arunima Misra, MD, Claire Z. Scott, MD, Jamal H. Mahar, MD, Savitri Fedson, MD, MA   +5 more
doaj   +1 more source

Transcription of brain natriuretic peptide and atrial natriuretic peptide genes in human tissues [PDF]

, 1994
We have compared the expression of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) genes in various human tissues using a quantitative polymerase chain reaction technique.
Nguyen, T., Nemer, M., Dagnino, Lina, Nemer, Mona, Nguyen, Than, Gerbes, Alexander L., Dagnino, L.   +6 more
core   +1 more source

Comprehensive exploration of unexplained dyspnoea in subjects with normal ejection fraction and low natriuretic peptides. [PDF]

ESC Heart Fail
Abstract Background Unexplained exertional dyspnoea without significant elevation of natriuretic peptides is common. One of the causes might be early heart failure with preserved ejection fraction (HFpEF). Aims This study aimed to characterize patients with exertional dyspnoea and normal/near‐to‐normal N‐terminal pro‐brain natriuretic peptide (NT ...
Berthelot E, Laouar T, Beurnier A, Hrynchynshyn N, Eicher JC, Tartière JM, Jourdain P, Lairez O, Gellen B.   +8 more
europepmc   +2 more sources

The interpretation of brain natriuretic peptide in critical care patients; will it ever be useful? [PDF]

, 2010
The measurement of B-type natriuretic peptide (BNP) is recommended for the diagnosis of decompensated heart failure, the prognosis of chronic heart failure is worse if BNP is increased and studies suggest that BNP is useful to guide therapy.
John Dixon, Philips, B, Dixon, J, Barbara Philips   +3 more
core   +1 more source

Blockade of the natriuretic peptide clearance receptor attenuates proteinuria in a mouse model of focal segmental glomerulosclerosis

Physiological Reports, 2021
Glomerular podocytes play a key role in proteinuric diseases. Accumulating evidence suggests that cGMP signaling has podocyte protective effects. The major source of cGMP generation in podocytes is natriuretic peptides.
Liming Wang, Yuping Tang, Anne F. Buckley, Robert F. Spurney   +3 more
doaj   +1 more source

Atrial natriuretic factor (ANF) and renin-aldosterone in volume regulation of patients with cirrhosis [PDF]

, 1989
The role of the atrial natriuretic factor and of the main counteracting sodium-retaining principle, the renin-aldosterone system, in acute volume regulation of cirrhosis of the liver has been investigated.
Arendt, Rainer M., Paumgartner, Gustav, Wernze, Heinrich, Riedel, Angelika, Gerbes, Alexander L., Sauerbruch, Tilman   +5 more
core   +1 more source