Results 51 to 60 of about 2,096 (139)

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri, Andrea Bordugo, Birute Burnyte, Alessandro Costetti, Maria‐Luz Couce, Luisa Diogo, Francois Feillet, D. Sean Froese, Benedetta Greco, Jean‐Louis Gueant, Luciana Hannibal, Friederike Hörster, Viktor Kožich, Giancarlo La Marca, Irini Manoli, Fanny Mochel, Lorenzo Orazi, Belén Pérez, Manuel Schiff, Bernd C. Schwahn, Ida Schwartz, Karolina M. Stepien, Jolanta Sykut‐Cegielska, Trine Tangeraas, Rolf H. Zetterström, Carlo Dionisi‐Vici, Martina Huemer   +26 more
wiley   +1 more source

A Non‐Channel Function of CFTR: Attenuating Mitochondrial Oxidative Stress and Cardiomyocyte Senescence via Stabilization by USP45

Aging Cell, Volume 25, Issue 7, July 2026.
USP45 stabilizes CFTR through deubiquitination, thereby activating PMCA, which inhibits calcium/chloride overload and mitochondrial oxidative stress in senescent cardiomyocytes, ultimately alleviating cardiomyocyte senescence. ABSTRACT Cardiomyocyte senescence drives cardiovascular disease, underscoring the need to define its molecular mechanisms.
Chun Chen, Longtan Jiang, Yuewen Qiu, Chong Liu, Xiao Long, Pengcui Wu, Liang Li, Haixia Xu, Ping Deng, Li Yang, Qiao Jin   +10 more
wiley   +1 more source

Morphological Control of Aurophilic Chains of Gold(I) Dithiolate Dimers With Alkali and Alkali Earth Cations

Chemistry – A European Journal, Volume 32, Issue 24, 23 June 2026.
Luminescent coordination polymers of Group 1 (Li, K, Cs) and 2 (Mg─Ba) cations with gold(I) iso‐maleonitriledithiolate ({Au2[S2C = C(CN)2]}2−) units were prepared; 1‐D aurophilic chains are present in all cases. The structures strongly depend on cation charge and size, with N‐cyano coordination observed in the Gp 1 and larger Gp 2 cations. Increasingly
Jefferson A. Pells, William W. L. Ho, Daniel B. Leznoff   +2 more
wiley   +1 more source

Toward Reliable Spectroscopic Analysis of Reaction Kinetics in Polaritonic Chemistry

Nanophotonics, Volume 15, Issue 11, 13 June 2026.
Vibrational strong coupling has been reported to modify chemical reaction rates, yet its mechanism remains unresolved. We expose pitfalls in UV/Vis‐based kinetic analyses and emphasize the need for standardized cavity protocols. ABSTRACT Recent reports suggest that chemical reaction rates can change inside an optical cavity.
Robrecht M. A. Vergauwe, J. Jussi Toppari, Gerrit Groenhof   +2 more
wiley   +1 more source

Emerging Trends in Organic Photoreactions Utilizing Disulfides

European Journal of Organic Chemistry, Volume 29, Issue 21, 4 June 2026.
Disulfides are versatile, nontoxic alternatives to metal photocatalysts. This review explores their role as photoactivated thiyl‐radical precursors and bifunctional catalysts (HAT/electron shuttling) in diverse transformations. Strategies for electronic tuning and development into recyclable heterogeneous materials are highlighted for sustainable ...
Sunil Kumar, Bolormaa Bayarkhuu, Hong Y. Cho, Jeehye Byun   +3 more
wiley   +1 more source

Strategies Toward Accessing Enantioenriched (Hetero)Benzo‐Fused 5‐ and 6‐ Membered Rings via Intermolecular Carbometalation

Angewandte Chemie, Volume 138, Issue 23, 1 June 2026.
The use of transition‐metal catalysts and design of chiral ligands have allowed chemists to access highly functionalized benzofused 5‐ and 6‐ membered rings in high yield and enantioselectivity. A common strategy used relies on an intermolecular carbometalation across alkynes and olefins, usually followed by a subsequent intramolecular carbometalation.
Clara Jans, Armaan Grewal, Xavier Abel‐Snape, Mark Lautens   +3 more
wiley   +2 more sources

Dual‐Site Catalysis in Electrocatalytic C–N Coupling: Challenges and Design Principles

ChemElectroChem, Volume 13, Issue 11, 3 June 2026.
This review examines dual‐site catalysis in electrocatalytic C─N coupling through four recurring challenges: energetic barriers, kinetic mismatch, selectivity loss, and systemic constraints. It highlights how rationally designed dual‐site catalysts cooperatively lower reaction barriers, synchronize intermediate generation, suppress competing pathways ...
Tao You, Jiacheng Li, Junyan Li, Guangqin Li   +3 more
wiley   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, Volume 15, Issue 22, 12 June 2026.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Magnetic Textiles: A Review of Materials, Fabrication, Properties, and Applications

Advanced Materials Technologies, Volume 11, Issue 12, 18 June 2026.
Magnetic textiles (M‐textiles) are emerging as a programmable materials platform that merges magnetic matter with hierarchical textile structures. This article consolidates magnetic material classes, textile architectures, and fabrication and magnetization strategies, revealing structure–property–function relationships that govern magneto‐mechanical ...
Li Ke, Moses Kumi, Xiaoming Tao, Junhong Pu   +3 more
wiley   +1 more source

Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury

Advanced Science, Volume 13, Issue 31, 4 June 2026.
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie, Gulimire Yilihan, Qiong Chen, Dachuan Lin, Zhen Liu, Mengyi Yuan, Yujia Wang, Haoteng Xu, Weishang Zhou, Wanxin Gong, Yueer Li, Chen Peng, Tong Yang, Peng Gao, Qing Liu, Xin‐Hua Feng, Mu Xiao, Chao Jiang   +17 more
wiley   +1 more source