Results 61 to 70 of about 89,262 (295)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Natural plague foci in Kazakhstan and places where blood samples from vaccinated people were collected.

open access: yes, 2019
Natural plague foci in Kazakhstan and places where blood samples from vaccinated people were collected.
Tatyana Bolger (6843455)   +6 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Zoologist Alekseev Anatoly Fedorovich (Crimean period of his life) [PDF]

open access: yesNovitates Theriologicae, 2022
An essay about a researcher who had developed professionally in Central Asia, where he worked for a quarter of a century in the Karakalpak branch of the Uzbek Anti-plague Station studying natural foci of plague.
Igor Evstafiev
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Present-Day Epidemiological-Epizootological Peculiarities of Natural Tularemia Foci in Altai

open access: yes, 2019
Relevance Natural tularemia foci are widespread in Altai Krai and Republic Altai and characterized by high functional stability. Aim. To study modern epidemiological and epizootological features of natural foci of tularemia in the Altai region Russia ...
A. K. Syngeeva   +8 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

DFR-Typing of Yersinia pestis Strains from the CIS Natural Foci

open access: yes, 2011
Different region analysis (DFR-typing) was used for characterization of 275 Y. pestis strains isolated mainly from the CIS natural plague foci. Genomovars (DFR-types) endemic for 27 natural foci were determined.
D. V. Efremenko   +7 more
core   +1 more source

Map of natural plague foci of the Caucasus, the Caspian and the Aral Sea regions.

open access: yes, 2023
Yellow color marks desert and semi-desert foci of the gerbil type, green–semi-desert and steppe foci of the souslik type, blue–high-mountain foci of the souslik type, pink–high-mountain foci of the vole type.
Galina A. Eroshenko (4538311)   +8 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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