Results 81 to 90 of about 436,148 (290)

Fluid Structure Interaction Using Modal Superposition and Lagrangian CFD

open access: yesJournal of Marine Science and Engineering
This study investigates the impact of fluid loads on the elastic deformation and dynamic response of linear structures. A weakly coupled modal solver is presented, which involves the solution of a dynamic equation of motion with external loads.
Manigandan Paneer   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Study of the Natural Frequencies of a Disc [PDF]

open access: yes, 2015
This thesis presents experimental methods designed to determine the natural frequencies of a disc in air and submerged in water. With the goal of showing the change in natural frequencies when the disc is submerged.
Aarønes, Truls Edvardsen
core   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Crack Detection of Fan Blade Based on Natural Frequencies

open access: yesInternational Journal of Rotating Machinery, 2018
A simple method was developed to detect damage based on a discrete mathematical model for fan blades using changes in natural frequencies combined with a fluid-structure analysis.
Mengyao Yu   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Determination natural frequencies of rotor induction machine [PDF]

open access: yes, 2010
In this paper three different methods of determination natural frequencies of rotor of induction machine SF 80-4A is presented and compared. The first one is analytical; the second one uses Finite Element Program.
Podhajecki, J., Szymaniec, S.
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Natural frequencies of two elementary rigid frames [PDF]

open access: yes, 1964
The natural frequencies of two elementary rigid frames, the rectangular bent and the two member frame, were determined for various ratios of length, moment of inertia, and mass per unit length of the vertical and horizontal members.
Shadden, James Arthur
core  

Natural Frequencies of Shear Deformable Plates by Polyharmonic Splines

open access: yesJournal of Applied Mathematics, 2013
We use the third-order shear deformation theory and a collocation technique with polyharmonic splines to predict natural frequencies of moderately thick isotropic plates.
A. J. M. Ferreira, A. M. Zenkour
doaj   +1 more source

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