Results 31 to 40 of about 143,552 (274)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Hydro-mechanical effects of deciduous forest on slope stability: First results from a case study in Western Norway [PDF]

E3S Web of Conferences
The use of vegetation as a nature-based solution for shallow landslide risk reduction is receiving increased attention in the scientific community, as plants can provide hydro-mechanical reinforcement of slopes.
DiBiagio Amanda, Capobianco Vittoria, Oen Amy, Tallaksen Lena M.   +3 more
doaj   +1 more source

Systematic human rights violations, traumatic events, daily stressors and mental health of Rohingya refugees in Bangladesh

Conflict and Health, 2020
Background Almost 900,000 Rohingya refugees currently reside in refugee camps in Southeastern Bangladesh. Prior to fleeing Myanmar, Rohingya experienced years of systematic human rights violations, in addition to other historical and more recent ...
Andrew Riley, Yasmin Akther, Mohammed Noor, Rahmat Ali, Courtney Welton-Mitchell   +4 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Coulomb stress changes associated with the M7.3 Maduo earthquake and implications for seismic hazards

Natural Hazards Research, 2021
On May 21, 2021, the M7.3 Maduo earthquake occurred within the Bayan Har Block, one of the most seismically active regions in the Tibetan Plateau. This aroused attention to the seismic hazards in this block.
Yujiang Li, Luyuan Huang, Rui Ding, Shuxin Yang, Lei Liu, Shimin Zhang, Haoqing Liu   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Coseismic Rupture Model and Tectonic Implications of the January 7 2022, Menyuan Mw 6.6 Earthquake Constraints from InSAR Observations and Field Investigation

Remote Sensing, 2022
A Mw 6.6 earthquake struck Menyuan, Qinghai, China, on 7 January 2022. To determine the rupture parameters of this event, the coseismic InSAR deformation fields were mapped and further employed to estimate the focal mechanism.
Yongsheng Li, Wenliang Jiang, Yujiang Li, Wenhao Shen, Zhongtai He, Bingquan Li, Qiang Li, Qisong Jiao, Yunfeng Tian   +8 more
doaj   +1 more source