Results 41 to 50 of about 643,109 (294)

Coseismic Rupture Model and Tectonic Implications of the January 7 2022, Menyuan Mw 6.6 Earthquake Constraints from InSAR Observations and Field Investigation

Remote Sensing, 2022
A Mw 6.6 earthquake struck Menyuan, Qinghai, China, on 7 January 2022. To determine the rupture parameters of this event, the coseismic InSAR deformation fields were mapped and further employed to estimate the focal mechanism.
Yongsheng Li, Wenliang Jiang, Yujiang Li, Wenhao Shen, Zhongtai He, Bingquan Li, Qiang Li, Qisong Jiao, Yunfeng Tian   +8 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Natural Hazard Overview: Flooding [PDF]

, 2018
The National Centre for Resilience supported the Met Office and their partner organisations in the production of a set of Natural Hazard Overviews. This factsheet is one of the set commissioned to meet a requirement for Scotland-specific information ...
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Natural hazards in Australia : floods [PDF]

, 2016
Floods are caused by a number of interacting factors, making it remarkably difficult to explain changes in flood hazard. This paper reviews the current understanding of historical trends and variability in flood hazard across Australia.
Ekstrom, Marie, Evans, Jason P., Jakob, Dörte, Johnson, Fiona, Kiem, Anthony S., Leonard, Michael, Rouillard, Alexandra, van Dijk, Albert, Westra, Seth, White, Christopher J.   +9 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The potential use of nature-based solutions as natural hazard mitigation measure for linear infrastructure in the Nordic Countries

Geoenvironmental Disasters
Background Reliable infrastructure is vital for Nordic societies, but they face escalating climate risks. Climate change is increasing magnitude and frequency of floods, storms, and landslides, making adaptive solutions crucial.
Vittoria Capobianco, Rosa Maria Palau, Anders Solheim, Kjersti Gisnås, Graham Gilbert, Per Danielsson, Peter van der Keur   +6 more
doaj   +1 more source

Coulomb stress changes associated with the M7.3 Maduo earthquake and implications for seismic hazards

Natural Hazards Research, 2021
On May 21, 2021, the M7.3 Maduo earthquake occurred within the Bayan Har Block, one of the most seismically active regions in the Tibetan Plateau. This aroused attention to the seismic hazards in this block.
Yujiang Li, Luyuan Huang, Rui Ding, Shuxin Yang, Lei Liu, Shimin Zhang, Haoqing Liu   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Natural hazards and disaster management in Pakistan [PDF]

, 2008
The present study explains the various concepts used in disaster management. The concepts explained include: Disaster, Hazard, Vulnerability, Capacity, Risk and Disaster Management Cycle.
Khan, Abuturab, Khan, Himayatullah
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