Results 91 to 100 of about 749,043 (396)

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

Molecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Association of Anger Expression-Out with NK Cell Counts in Colorectal Cancer Patients

Acta Médica Portuguesa, 2018
Introduction: There is growing evidence describing the relation between psychological factors and the progression of colorectal cancer. Several mechanisms have been proposed but the one showing more promising evidence relies on the modulation of the ...
Estela Kakoo-Brioso, Luís Costa, Sílvia Ouakinin   +2 more
doaj   +1 more source

RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry. [PDF]

, 2012
The NKG2D stimulatory receptor expressed by natural killer cells and T cell subsets recognizes cell surface ligands that are induced on transformed and infected cells and facilitate immune rejection of tumor cells.
Hsiung, Benjamin, Jung, Heiyoun, Pestal, Kathleen, Procyk, Emily, RAULET, David H.   +4 more
core   +2 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

“Multi-Omics” Analyses of the Development and Function of Natural Killer Cells

Frontiers in Immunology, 2017
For over four decades, our understanding of natural killer (NK) cells has evolved from the original description of cluster of differentiation (CD)56+CD3− to establishing NK cells as an important subset of innate lymphocytes in the host’s surveillance ...
Yonggang Zhou, Xiuxiu Xu, Xiuxiu Xu, Zhigang Tian, Zhigang Tian, Haiming Wei, Haiming Wei   +6 more
doaj   +1 more source

Natural killer cell-related gene signature predicts malignancy of glioma and the survival of patients

BMC Cancer, 2022
Background Natural killer (NK) cells-based therapies are one of the most promising strategies against cancer. The aim of this study is to investigate the natural killer cell related genes and its prognostic value in glioma.
Chenglong Li, Fangkun Liu, Lunquan Sun, Zhixiong Liu, Yu Zeng   +4 more
doaj   +1 more source

Toxoplasma gondii infection drives conversion of NK cells into ILC1-like cells [PDF]

, 2019
Innate lymphoid cells (ILCs) were originally classified based on their cytokine profiles, placing natural killer (NK) cells and ILC1s together, but recent studies support their separation into different lineages at steady-state.
Andhey, Prabhakar, Artyomov, Maxim, Bern, Michael, Collins, Patrick, Colonna, Marco, Hershey, Maxwell, Murphy, Kenneth M, Oltz, Eugene, Park, Eugene, Patel, Swapneel, Plougastel-Douglas, Beatrice, Porter, Sophia, Sibley, L David, Wang, Qiuling, Yokoyama, Wayne M, Zaitsev, Konstantin   +15 more
core   +1 more source

Invariant NKT cells and rheumatic disease: Focus on primary sjogren syndrome [PDF]

, 2019
Primary Sjogren syndrome (pSS) is a complex autoimmune disease mainly affecting salivary and lacrimal glands. Several factors contribute to pSS pathogenesis; in particular, innate immunity seems to play a key role in disease etiology.
Barbera L. L., Ciccia F., Guggino G., Pizzo M. L., Rizzo C., Sireci G.   +5 more
core   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Structural equation model testing and the quality of natural killer cell activity measurements

BMC Medical Research Methodology, 2005
Background Browne et al. [Browne, MacCallum, Kim, Andersen, Glaser: When fit indices and residuals are incompatible. Psychol Methods 2002] employed a structural equation model of measurements of target cell lysing by natural killer cells as an example ...
Levers Merry-Jo D, Cummings Greta G, Pazderka-Robinson Hannah, Hayduk Leslie A, Beres Melanie A   +4 more
doaj   +1 more source